Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Hyaluronan synthase 1

Gene

Has1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BRENDAi2.4.1.212. 5301.
ReactomeiR-RNO-2142850. Hyaluronan biosynthesis and export.

Protein family/group databases

CAZyiGT2. Glycosyltransferase Family 2.

Names & Taxonomyi

Protein namesi
Submitted name:
Hyaluronan synthase 1Imported
Gene namesi
Name:Has1Imported
Synonyms:HAS1Imported, LOC282821Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi708528. Has1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 40HelicalSequence analysisAdd BLAST20
Transmembranei52 – 75HelicalSequence analysisAdd BLAST24
Transmembranei410 – 429HelicalSequence analysisAdd BLAST20
Transmembranei435 – 457HelicalSequence analysisAdd BLAST23
Transmembranei464 – 485HelicalSequence analysisAdd BLAST22
Transmembranei505 – 523HelicalSequence analysisAdd BLAST19
Transmembranei544 – 566HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000010994.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014824.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2571. Eukaryota.
COG1215. LUCA.
GeneTreeiENSGT00390000010337.
HOGENOMiHOG000112847.
HOVERGENiHBG000189.
KOiK00752.
OMAiDWSGPSR.
OrthoDBiEOG091G04P3.
TreeFamiTF332506.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiView protein in InterPro
IPR028385. HAS1.
IPR029044. Nucleotide-diphossugar_trans.
PANTHERiPTHR22913:SF4. PTHR22913:SF4. 1 hit.
SUPFAMiSSF53448. SSF53448. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8CH93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQDMPKPSE AARCCSGLAR RVLTITFALL ILGLMTWAYA AGVPLASDPY
60 70 80 90 100
GLLAFGLYGA FLSAHLVAQS LFAYLEHRRV TVAARRAFAK GPLDAATARS
110 120 130 140 150
VALTISAYQE DPTYLRQCLT SARALLYPRT RLRVLMVVDG NRAEDLYMVD
160 170 180 190 200
MFREVFADED PATYVWDGNY HQPWEPAEAA GAVGEGAYRE VEAEDPGRLA
210 220 230 240 250
VEALVRTRRC VCVAQRWGGK REVMYTAFKA LGDSVDYVQV CDSDTRLDPM
260 270 280 290 300
ALLELVRVLD EDPRVGAVGG DVRILNPLDS WVSFLSSLRY WVAFNVERAC
310 320 330 340 350
QSYFHCVSCI SGPLGLYRNN LLQQFLEAWY NQKFLGTHCT FGDDRHLTNR
360 370 380 390 400
MLSMGYATKY TSRSRCYSET PSSFLRWLSQ QTRWSKSYFR EWLYNALWWH
410 420 430 440 450
RHHAWMTYEA VVSGLFPFFV AATVLRLFYA GRPWALLWVL LCVQGVALAK
460 470 480 490 500
AAFAAWLRGC LRMVLLSLYA PLYMCGLLPA KFLALVTMNQ SGWGTSGRKK
510 520 530 540 550
LAANYVPVLP LALWALLLLG GLIRSVAQEV RADWSGPSRA AEAYHLAAGA
560 570 580
SAYVAYWVIM LTIYWVGVRR LCRRRSGGYR VQV
Length:583
Mass (Da):65,725
Last modified:March 1, 2003 - v1
Checksum:i35513C6B21DE4E8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07001847 Genomic DNA. No translation available.
AB097568 mRNA. Translation: BAC43730.1.
RefSeqiNP_758826.1. NM_172323.1.
UniGeneiRn.91138.

Genome annotation databases

EnsembliENSRNOT00000014824; ENSRNOP00000014824; ENSRNOG00000010994.
GeneIDi282821.
KEGGirno:282821.
UCSCiRGD:708528. rat.

Similar proteinsi

Entry informationi

Entry nameiQ8CH93_RAT
AccessioniPrimary (citable) accession number: Q8CH93
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 22, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported