Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Calcium homeostasis endoplasmic reticulum protein

Gene

Cherp

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in calcium homeostasis, growth and proliferation.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Calcium homeostasis endoplasmic reticulum protein
Alternative name(s):
SR-related CTD-associated factor 6
Gene namesi
Name:CherpImported
Synonyms:Scaf6Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:106417 Cherp

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002994931 – 936Calcium homeostasis endoplasmic reticulum proteinAdd BLAST936

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei18N6-acetyllysineBy similarity1
Modified residuei723PhosphotyrosineCombined sources1
Modified residuei822PhosphoserineCombined sources1
Modified residuei824PhosphoserineCombined sources1
Modified residuei826PhosphoserineCombined sources1
Modified residuei828PhosphothreonineCombined sources1
Modified residuei837PhosphoserineBy similarity1
Cross-linki853Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei864PhosphoserineBy similarity1
Modified residuei866PhosphoserineBy similarity1
Cross-linki881Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei888N6-acetyllysineBy similarity1
Modified residuei913PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ8CGZ0
MaxQBiQ8CGZ0
PaxDbiQ8CGZ0
PRIDEiQ8CGZ0

PTM databases

iPTMnetiQ8CGZ0
PhosphoSitePlusiQ8CGZ0

Expressioni

Gene expression databases

CleanExiMM_CHERP

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
SF1Q156373EBI-2366446,EBI-744603From Homo sapiens.

GO - Molecular functioni

Protein-protein interaction databases

BioGridi205695, 2 interactors
IntActiQ8CGZ0, 3 interactors
MINTiQ8CGZ0
STRINGi10090.ENSMUSP00000078469

Structurei

3D structure databases

ProteinModelPortaliQ8CGZ0
SMRiQ8CGZ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati15 – 57SURP motifSequence analysisAdd BLAST43
Domaini149 – 289CIDPROSITE-ProRule annotationAdd BLAST141
Domaini850 – 900G-patchPROSITE-ProRule annotationAdd BLAST51

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi279 – 355Gln-richSequence analysisAdd BLAST77
Compositional biasi343 – 691Pro-richSequence analysisAdd BLAST349
Compositional biasi727 – 825Arg-richSequence analysisAdd BLAST99

Phylogenomic databases

eggNOGiKOG4368 Eukaryota
ENOG410YVN1 LUCA
HOGENOMiHOG000010294
HOVERGENiHBG052716
InParanoidiQ8CGZ0
KOiK12841
PhylomeDBiQ8CGZ0

Family and domain databases

Gene3Di1.10.10.790, 1 hit
1.25.40.90, 1 hit
InterProiView protein in InterPro
IPR006569 CID_dom
IPR008942 ENTH_VHS
IPR000467 G_patch_dom
IPR006903 RNA_pol_II-bd
IPR000061 Surp
IPR035967 SWAP/Surp_sf
PfamiView protein in Pfam
PF04818 CTD_bind, 1 hit
PF01585 G-patch, 1 hit
PF01805 Surp, 1 hit
SMARTiView protein in SMART
SM00443 G_patch, 1 hit
SM00648 SWAP, 1 hit
SUPFAMiSSF109905 SSF109905, 1 hit
SSF48464 SSF48464, 1 hit
PROSITEiView protein in PROSITE
PS51391 CID, 1 hit
PS50174 G_PATCH, 1 hit
PS50128 SURP, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CGZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMPMPPDDQ ELRNVIDKLA QFVARNGPEF EKMTMEKQKD NPKFSFLFGG
60 70 80 90 100
EFYSYYKCKL ALEQQQLICK QQAPELEPTS AMPPLPQPPL APTASLTPAQ
110 120 130 140 150
GTPSMDELIQ QSQWSLQQQE QHLLALRQEQ VTTAVAHAVE QQMQKLLEET
160 170 180 190 200
QLDMSEFDNL LQPIIDTCTK DAISAGKNWM FSNAKSPPHC ELMAGHLRNR
210 220 230 240 250
ITADGAHFEL RLHLIYLIND VLHHCQRKQA RELLAALQKV VVPIYCTSFL
260 270 280 290 300
AVEEDKQQKI ARLLQLWEKN GYFDDSIIQQ LQSPALGLGQ YQATLINEYS
310 320 330 340 350
SVVQPVQLAF QQQIQSLKTQ HEEFVSSLAQ QQQQQQQQQQ QQPQPQPQPQ
360 370 380 390 400
IQLPQMEADV KATPPPPAPP PASAPAPTIP PTTQPDDNKP PIQMPGSSEY
410 420 430 440 450
DTSAGVQDPA AAGPRGPGPH EQIPPNKPPW FDQPHPVAPW GQQQPPEQPP
460 470 480 490 500
YPHHQGGPPH CPPWNNSHEG MWGEQRGDPG WNGQRDAPWN NQPDPNWNNQ
510 520 530 540 550
FEGPWNNQHE PPPWGGAQRE PPFRMQRPPH FRGPFPPHQQ HPQFNQPPHP
560 570 580 590 600
HNFNRFPPRF MQDDFPPRHP FERPPYPHRF DYPQGDFPAD MGPPHHHPGH
610 620 630 640 650
RMPHPGINEH PPWAGPQHPD FGPPPHGFNG QPPHMRRQGP PHINHDDPSL
660 670 680 690 700
VPNVPYFDLP AGLMAPLVKL EDHEYKPLDP KDIRLPPPMP PSERLLAAVE
710 720 730 740 750
AFYSPPSHDR PRNSEGWEQN GLYEFFRAKM RARRRKGQEK RNSGPSRSRS
760 770 780 790 800
RSKSRGRSSS RSSSRSSKSS RSSSRSHSRS RSRSSSRSRS RSRSRSRSSR
810 820 830 840 850
SRSRSRSRSR SKSYSPGRRR RSRSRSPTPP SAAGLGSNSA PPIPDSRLGE
860 870 880 890 900
ENKGHQMLVK MGWSGSGGLG AKEQGIQDPI KGGDVRDKWD QYKGVGVALD
910 920 930
DPYENYRRNK SYSFIARMKA RDEFSTFGTR KEEKED
Length:936
Mass (Da):106,169
Last modified:March 1, 2003 - v1
Checksum:i8C29DF0822CA9EB3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti348 – 349Missing in BC020488 (PubMed:15489334).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF536541 mRNA Translation: AAN77182.1
BC020488 mRNA No translation available.
RefSeqiNP_613051.3, NM_138585.3
UniGeneiMm.30136

Genome annotation databases

GeneIDi27967
KEGGimmu:27967
UCSCiuc009mgb.1 mouse

Similar proteinsi

Entry informationi

Entry nameiCHERP_MOUSE
AccessioniPrimary (citable) accession number: Q8CGZ0
Secondary accession number(s): Q8K291, Q8VCD2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health