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Protein
Submitted name:

Glandular kallikrein KLK13

Gene

Klk13

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • endopeptidase activity Source: MGI
  • hydrolase activity Source: UniProtKB
  • serine-type endopeptidase activity Source: GO_Central

GO - Biological processi

  • protein processing Source: MGI

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-6809371 Formation of the cornified envelope

Protein family/group databases

MEROPSiS01.306

Names & Taxonomyi

Protein namesi
Submitted name:
Glandular kallikrein KLK13Imported
Submitted name:
Kallikrein lImported
Submitted name:
Kallikrein-related-peptidase 13Imported
Gene namesi
Name:Klk13Imported
Synonyms:Egfbp2Imported, KlnlImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:3615275 Klk13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501458888219 – 276Sequence analysisAdd BLAST258

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000054046

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000065308

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 264Peptidase S1InterPro annotationAdd BLAST228

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118862
HOGENOMiHOG000251820
HOVERGENiHBG013304
KOiK09463
OMAiLWIRETI
OrthoDBiEOG091G0DF7
TreeFamiTF331065

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CGR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWPLVATIAC LTLALSEGIS RDYPKILNGT NGTSGFLPGG YTCLPHSQPW
60 70 80 90 100
QAALLIRGRL LCGGVLVHPK WVLTAAHCRK DGYTVHLGKH ALGRVENGEQ
110 120 130 140 150
AMEVVRSIPH PEYQVTPTHL NHDHDIMLLE LKSPVQLSSH VRTLKLSADD
160 170 180 190 200
CLPTGTCCRV SGWGTTTSPQ VNYPKTLQCA NIELRSDEEC RQVYPGKITA
210 220 230 240 250
NMLCAGTKEG GKDSCEGDSG GPLICNGKLY GIISWGDFPC GQPNRPGVYT
260 270
RVSKYLRWIR EIIRNTPEQR WTKGTQ
Length:276
Mass (Da):30,360
Last modified:March 1, 2003 - v1
Checksum:i33E189C67492FDCA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151989 Genomic DNA No translation available.
AY152432 Genomic DNA Translation: AAN78420.1
AB981045 mRNA Translation: BAQ21990.1
LT631608 Genomic DNA Translation: SFW93255.1
RefSeqiNP_001034131.2, NM_001039042.2
XP_006541118.1, XM_006541055.3
XP_006541119.1, XM_006541056.3
UniGeneiMm.389891

Genome annotation databases

EnsembliENSMUST00000066834; ENSMUSP00000065308; ENSMUSG00000054046
GeneIDi626834
KEGGimmu:626834
UCSCiuc009gnk.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ8CGR6_MOUSE
AccessioniPrimary (citable) accession number: Q8CGR6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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