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Q8CGR6

- Q8CGR6_MOUSE

UniProt

Q8CGR6 - Q8CGR6_MOUSE

Protein
Submitted name:

Epidermal growth factor-binding protein type B

Gene

Klk13

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. endopeptidase activity Source: MGI
    2. hydrolase activity Source: UniProtKB
    3. serine-type endopeptidase activity Source: RefGenome

    GO - Biological processi

    1. protein processing Source: MGI
    2. proteolysis Source: RefGenome

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine proteaseUniRule annotation

    Protein family/group databases

    MEROPSiS01.306.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Epidermal growth factor-binding protein type BImported
    Submitted name:
    Glandular kallikrein KLK13Imported
    Gene namesi
    Name:Klk13Imported
    Synonyms:Egfbp2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:3615275. Klk13.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB
    2. extracellular space Source: MGI
    3. secretory granule Source: MGI

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ8CGR6.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG5640.
    GeneTreeiENSGT00750000117409.
    HOGENOMiHOG000251820.
    HOVERGENiHBG013304.
    InParanoidiQ8CGR6.
    KOiK09463.
    OMAiTNAGDFA.
    OrthoDBiEOG75B84T.
    TreeFamiTF331065.

    Family and domain databases

    InterProiIPR001254. Peptidase_S1.
    IPR018114. Peptidase_S1_AS.
    IPR001314. Peptidase_S1A.
    IPR009003. Trypsin-like_Pept_dom.
    [Graphical view]
    PfamiPF00089. Trypsin. 1 hit.
    [Graphical view]
    PRINTSiPR00722. CHYMOTRYPSIN.
    SMARTiSM00020. Tryp_SPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF50494. SSF50494. 1 hit.
    PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
    PS00134. TRYPSIN_HIS. 1 hit.
    PS00135. TRYPSIN_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8CGR6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWPLVATIAC LTLALSEGIS RDYPKILNGT NGTSGFLPGG YTCLPHSQPW    50
    QAALLIRGRL LCGGVLVHPK WVLTAAHCRK DGYTVHLGKH ALGRVENGEQ 100
    AMEVVRSIPH PEYQVTPTHL NHDHDIMLLE LKSPVQLSSH VRTLKLSADD 150
    CLPTGTCCRV SGWGTTTSPQ VNYPKTLQCA NIELRSDEEC RQVYPGKITA 200
    NMLCAGTKEG GKDSCEGDSG GPLICNGKLY GIISWGDFPC GQPNRPGVYT 250
    RVSKYLRWIR EIIRNTPEQR WTKGTQ 276
    Length:276
    Mass (Da):30,360
    Last modified:March 1, 2003 - v1
    Checksum:i33E189C67492FDCA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151989 Genomic DNA. No translation available.
    AY152432 Genomic DNA. Translation: AAN78420.1.
    RefSeqiNP_001034131.2. NM_001039042.2.
    XP_006541118.1. XM_006541055.1.
    XP_006541119.1. XM_006541056.1.
    UniGeneiMm.389891.

    Genome annotation databases

    EnsembliENSMUST00000066834; ENSMUSP00000065308; ENSMUSG00000054046.
    GeneIDi626834.
    KEGGimmu:626834.
    UCSCiuc009gnk.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151989 Genomic DNA. No translation available.
    AY152432 Genomic DNA. Translation: AAN78420.1 .
    RefSeqi NP_001034131.2. NM_001039042.2.
    XP_006541118.1. XM_006541055.1.
    XP_006541119.1. XM_006541056.1.
    UniGenei Mm.389891.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi S01.306.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000066834 ; ENSMUSP00000065308 ; ENSMUSG00000054046 .
    GeneIDi 626834.
    KEGGi mmu:626834.
    UCSCi uc009gnk.1. mouse.

    Organism-specific databases

    CTDi 26085.
    MGIi MGI:3615275. Klk13.

    Phylogenomic databases

    eggNOGi COG5640.
    GeneTreei ENSGT00750000117409.
    HOGENOMi HOG000251820.
    HOVERGENi HBG013304.
    InParanoidi Q8CGR6.
    KOi K09463.
    OMAi TNAGDFA.
    OrthoDBi EOG75B84T.
    TreeFami TF331065.

    Miscellaneous databases

    NextBioi 419122.
    PROi Q8CGR6.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8CGR6.

    Family and domain databases

    InterProi IPR001254. Peptidase_S1.
    IPR018114. Peptidase_S1_AS.
    IPR001314. Peptidase_S1A.
    IPR009003. Trypsin-like_Pept_dom.
    [Graphical view ]
    Pfami PF00089. Trypsin. 1 hit.
    [Graphical view ]
    PRINTSi PR00722. CHYMOTRYPSIN.
    SMARTi SM00020. Tryp_SPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50494. SSF50494. 1 hit.
    PROSITEi PS50240. TRYPSIN_DOM. 1 hit.
    PS00134. TRYPSIN_HIS. 1 hit.
    PS00135. TRYPSIN_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Organization and evolution of the glandular kallikrein locus in Mus musculus."
      Olsson A.Y., Lundwall A.
      Biochem. Biophys. Res. Commun. 299:305-311(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. Adams M., Mural R.
      Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8CGR6_MOUSE
    AccessioniPrimary (citable) accession number: Q8CGR6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3