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Q8CGR6

- Q8CGR6_MOUSE

UniProt

Q8CGR6 - Q8CGR6_MOUSE

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Protein
Submitted name:

Epidermal growth factor-binding protein type B

Gene

Klk13

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. endopeptidase activity Source: MGI
  2. hydrolase activity Source: UniProtKB
  3. serine-type endopeptidase activity Source: InterPro

GO - Biological processi

  1. protein processing Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotation

Protein family/group databases

MEROPSiS01.306.

Names & Taxonomyi

Protein namesi
Submitted name:
Epidermal growth factor-binding protein type BImported
Submitted name:
Glandular kallikrein KLK13Imported
Gene namesi
Name:Klk13Imported
Synonyms:Egfbp2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:3615275. Klk13.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. extracellular space Source: MGI
  3. extracellular vesicular exosome Source: Ensembl
  4. secretory granule Source: MGI
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriQ8CGR6.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5640.
GeneTreeiENSGT00760000118862.
HOGENOMiHOG000251820.
HOVERGENiHBG013304.
KOiK09463.
OMAiTNAGDFA.
OrthoDBiEOG75B84T.
TreeFamiTF331065.

Family and domain databases

InterProiIPR001254. Peptidase_S1.
IPR018114. Peptidase_S1_AS.
IPR001314. Peptidase_S1A.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CGR6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWPLVATIAC LTLALSEGIS RDYPKILNGT NGTSGFLPGG YTCLPHSQPW
60 70 80 90 100
QAALLIRGRL LCGGVLVHPK WVLTAAHCRK DGYTVHLGKH ALGRVENGEQ
110 120 130 140 150
AMEVVRSIPH PEYQVTPTHL NHDHDIMLLE LKSPVQLSSH VRTLKLSADD
160 170 180 190 200
CLPTGTCCRV SGWGTTTSPQ VNYPKTLQCA NIELRSDEEC RQVYPGKITA
210 220 230 240 250
NMLCAGTKEG GKDSCEGDSG GPLICNGKLY GIISWGDFPC GQPNRPGVYT
260 270
RVSKYLRWIR EIIRNTPEQR WTKGTQ
Length:276
Mass (Da):30,360
Last modified:March 1, 2003 - v1
Checksum:i33E189C67492FDCA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC151989 Genomic DNA. No translation available.
AY152432 Genomic DNA. Translation: AAN78420.1.
RefSeqiNP_001034131.2. NM_001039042.2.
XP_006541118.1. XM_006541055.1.
XP_006541119.1. XM_006541056.1.
UniGeneiMm.389891.

Genome annotation databases

EnsembliENSMUST00000066834; ENSMUSP00000065308; ENSMUSG00000054046.
GeneIDi626834.
KEGGimmu:626834.
UCSCiuc009gnk.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC151989 Genomic DNA. No translation available.
AY152432 Genomic DNA. Translation: AAN78420.1 .
RefSeqi NP_001034131.2. NM_001039042.2.
XP_006541118.1. XM_006541055.1.
XP_006541119.1. XM_006541056.1.
UniGenei Mm.389891.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi S01.306.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000066834 ; ENSMUSP00000065308 ; ENSMUSG00000054046 .
GeneIDi 626834.
KEGGi mmu:626834.
UCSCi uc009gnk.1. mouse.

Organism-specific databases

CTDi 26085.
MGIi MGI:3615275. Klk13.

Phylogenomic databases

eggNOGi COG5640.
GeneTreei ENSGT00760000118862.
HOGENOMi HOG000251820.
HOVERGENi HBG013304.
KOi K09463.
OMAi TNAGDFA.
OrthoDBi EOG75B84T.
TreeFami TF331065.

Miscellaneous databases

NextBioi 419122.
PROi Q8CGR6.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8CGR6.

Family and domain databases

InterProi IPR001254. Peptidase_S1.
IPR018114. Peptidase_S1_AS.
IPR001314. Peptidase_S1A.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view ]
Pfami PF00089. Trypsin. 1 hit.
[Graphical view ]
PRINTSi PR00722. CHYMOTRYPSIN.
SMARTi SM00020. Tryp_SPc. 1 hit.
[Graphical view ]
SUPFAMi SSF50494. SSF50494. 1 hit.
PROSITEi PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Organization and evolution of the glandular kallikrein locus in Mus musculus."
    Olsson A.Y., Lundwall A.
    Biochem. Biophys. Res. Commun. 299:305-311(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Adams M., Mural R.
    Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8CGR6_MOUSE
AccessioniPrimary (citable) accession number: Q8CGR6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3