Q8CGR6 (Q8CGR6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glandular kallikrein KLK13 EMBL AAN78420.1

Submitted name:
Protein Klk13 Ensembl ENSMUSP00000065308

Gene names

Name:	Klk13 MGI 3615275 Ensembl ENSMUSP00000065308
Synonyms:	Egfbp2 MGI 95292

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S1 family. RuleBase RU000360

Ontologies

Keywords
Molecular function	Hydrolase Protease Serine protease RuleBase RU004260
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein processing Inferred from direct assay PubMed 16423834. Source: MGI proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular space Inferred from direct assay PubMed 16423834. Source: MGI secretory granule Inferred from direct assay PubMed 16423834. Source: MGI
Molecular_function	endopeptidase activity Inferred from direct assay PubMed 16423834. Source: MGI serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8CGR6 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 33E189C67492FDCA	FASTA	276	30,360
	10 20 30 40 50 60 MWPLVATIAC LTLALSEGIS RDYPKILNGT NGTSGFLPGG YTCLPHSQPW QAALLIRGRL 70 80 90 100 110 120 LCGGVLVHPK WVLTAAHCRK DGYTVHLGKH ALGRVENGEQ AMEVVRSIPH PEYQVTPTHL 130 140 150 160 170 180 NHDHDIMLLE LKSPVQLSSH VRTLKLSADD CLPTGTCCRV SGWGTTTSPQ VNYPKTLQCA 190 200 210 220 230 240 NIELRSDEEC RQVYPGKITA NMLCAGTKEG GKDSCEGDSG GPLICNGKLY GIISWGDFPC 250 260 270 GQPNRPGVYT RVSKYLRWIR EIIRNTPEQR WTKGTQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Organization and evolution of the glandular kallikrein locus in Mus musculus." Olsson A.Y., Lundwall A. Biochem. Biophys. Res. Commun. 299:305-311(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Adams M., Mural R. Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000065308.
[4]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000065308.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC151989 Genomic DNA. No translation available. AY152432 Genomic DNA. Translation: AAN78420.1.
IPI	IPI00338790.
RefSeq	NP_001034131.2. NM_001039042.2.
UniGene	Mm.389891.
3D structure databases
SMR	Q8CGR6. Positions 26-264.
ModBase	Search...
Protein family/group databases
MEROPS	S01.306.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000066834; ENSMUSP00000065308; ENSMUSG00000054046.
GeneID	626834.
KEGG	mmu:626834.
UCSC	uc009gnk.1. mouse.
Organism-specific databases
CTD	26085.
MGI	MGI:3615275. Klk13.
Phylogenomic databases
eggNOG	COG5640.
GeneTree	ENSGT00690000101721.
HOGENOM	HOG000251820.
HOVERGEN	HBG013304.
InParanoid	Q8CGR6.
KO	K09463.
OMA	QCANIPL.
OrthoDB	EOG4XKV7F.
Gene expression databases
Genevestigator	Q8CGR6.
Family and domain databases
InterPro	IPR001254. Peptidase_S1. IPR018114. Peptidase_S1_AS. IPR001314. Peptidase_S1A. IPR009003. Trypsin-like_Pept_dom. [Graphical view]
Pfam	PF00089. Trypsin. 1 hit. [Graphical view]
PRINTS	PR00722. CHYMOTRYPSIN.
SMART	SM00020. Tryp_SPc. 1 hit. [Graphical view]
SUPFAM	SSF50494. Pept_Ser_Cys. 1 hit.
PROSITE	PS50240. TRYPSIN_DOM. 1 hit. PS00134. TRYPSIN_HIS. 1 hit. PS00135. TRYPSIN_SER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	419122.
SOURCE	Search...

Entry information

Entry name

Q8CGR6_MOUSE

Accession

Primary (citable) accession number: Q8CGR6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 29, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)