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Protein

BCL-6 corepressor

Gene

Bcor

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2) (By similarity).By similarity

GO - Molecular functioni

  1. heat shock protein binding Source: MGI
  2. histone deacetylase binding Source: MGI
  3. transcription corepressor activity Source: MGI
  4. transcription factor binding Source: MGI
  5. transcription regulatory region DNA binding Source: MGI
  6. ubiquitin-protein transferase activity Source: Ensembl

GO - Biological processi

  1. heart development Source: MGI
  2. histone H2A monoubiquitination Source: MGI
  3. negative regulation of bone mineralization Source: MGI
  4. negative regulation of histone H3-K36 methylation Source: MGI
  5. negative regulation of histone H3-K4 methylation Source: MGI
  6. negative regulation of tooth mineralization Source: MGI
  7. negative regulation of transcription, DNA-templated Source: MGI
  8. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  9. odontogenesis Source: MGI
  10. palate development Source: MGI
  11. specification of axis polarity Source: MGI
  12. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
BCL-6 corepressor
Short name:
BCoR
Gene namesi
Name:Bcor
Synonyms:Kiaa1575
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1918708. Bcor.

Subcellular locationi

  1. Nucleus 1 Publication

GO - Cellular componenti

  1. nucleus Source: MGI
  2. PcG protein complex Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 17591759BCL-6 corepressorPRO_0000066979Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei336 – 3361PhosphoserineBy similarity
Modified residuei340 – 3401PhosphoserineBy similarity
Modified residuei365 – 3651PhosphoserineBy similarity
Modified residuei367 – 3671PhosphoserineBy similarity
Modified residuei392 – 3921N6-acetyllysineBy similarity
Modified residuei423 – 4231PhosphoserineBy similarity
Modified residuei1143 – 11431PhosphoserineBy similarity
Modified residuei1413 – 14131PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ8CGN4.
PaxDbiQ8CGN4.
PRIDEiQ8CGN4.

PTM databases

PhosphoSiteiQ8CGN4.

Expressioni

Tissue specificityi

Expressed in heart, liver, lung, skeletal muscle, spleen and testis.1 Publication

Gene expression databases

BgeeiQ8CGN4.
CleanExiMM_BCOR.
ExpressionAtlasiQ8CGN4. baseline and differential.
GenevestigatoriQ8CGN4.

Interactioni

Subunit structurei

Interacts with BCL6; the interaction is direct. Forms ternary complexes with BCL6 and SMRT/NCOR2 on selected target genes promoters; potently repress expression. Can interact with HDAC1, HDAC3 and HDAC5. Interacts with PCGF1; the interaction is direct. Interacts with KDM2B. Component of an approximative 800 kDa repressive BCOR complex at least composed of BCOR, RYBP, PCGF1, RING1, RNF2/RING2, KDM2B and SKP1. Isoform 1 may interact with MLLT3/AF9.1 Publication

Protein-protein interaction databases

BioGridi214722. 8 interactions.
DIPiDIP-29852N.
IntActiQ8CGN4. 3 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ8CGN4.
SMRiQ8CGN4. Positions 1467-1583, 1640-1752.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati1466 – 149934ANK 1Add
BLAST
Repeati1500 – 152930ANK 2Add
BLAST
Repeati1533 – 156230ANK 3Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni498 – 51417Interaction with BCL6By similarityAdd
BLAST
Regioni1638 – 1752115Necessary and sufficient for interaction with PCGF1By similarityAdd
BLAST

Sequence similaritiesi

Belongs to the BCOR family.Curated
Contains 3 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiCOG0666.
GeneTreeiENSGT00760000119090.
HOVERGENiHBG050682.
InParanoidiQ8CGN4.
OMAiSSCPRMG.
OrthoDBiEOG7KWSGQ.
PhylomeDBiQ8CGN4.
TreeFamiTF333317.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8CGN4-1) [UniParc]FASTAAdd to basket

Also known as: A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLSATPLYGN VHSWMNSERV RMCGTSEDRK IPVNDGDASK ARLELREETP
60 70 80 90 100
LSHSVVDTSG AHRIDGLAAL SMDRTGLIRE GLRVPGNIVY SGLCGLGSEK
110 120 130 140 150
GREATPSSLS GLGFSSERNP EMQFKPNTPE TVEASAVSGK PPNGFSAIYK
160 170 180 190 200
TPPGIQKSAV ATAESLGLDR PASDKQSPLN INGASYLRLP WVNPYMEGAT
210 220 230 240 250
PAIYPFLDSP NKYSLNMYKA LLPQQSYGLA QPLYSPVCTS GERFLYLPPP
260 270 280 290 300
HYVNPHIPSS LASPMRLSTP SASAAIPPLV HCSDKSLPWK MGVNPGNPVD
310 320 330 340 350
SHSYPHIQNS KQPRVTSAKA VNSGLPGDTA LLLPPSPRPS ARVHLPTQPA
360 370 380 390 400
AETYSEFHKH YPRISTSPSV TLTKPYMTAN SEFSTSRLSN GKYPKALDGG
410 420 430 440 450
DCAQSMPGHT RKTTVQDRKD GGSPPLLEKQ TVTKDVTDKP LDLSSKVVDA
460 470 480 490 500
DASKGDHMKK MAPTVLVHSR AASGLVLSGS EIPKETLSPP GNGCSIYRSE
510 520 530 540 550
IISTAPSSWV VPGPSPNEEN NGKSLSLKNK ALDWAIPQQR SSSCPRMGGT
560 570 580 590 600
DAVVTNVSGS VSSSGRPASA SPAPNANANA DGTKTSRSSV DTTPSVIQHV
610 620 630 640 650
GQPSSTPAKH GGSTSSKGAK ANPEPSFKAS ENGLPPTSIF LSPNEAFRSP
660 670 680 690 700
AIPYPRSYLP YAAPEGIALS PLSLHGKGPV YPHPVLLPNG SLFPGHLAPK
710 720 730 740 750
PGLPYGLHTS RPEFVTYQDA LGLGMVHPML IPHTPIEITK EEKPERRSRS
760 770 780 790 800
HERARYEDPT LRSRFSEMLE ASSTKLHPEV PTDKNLKPNS SWNQGKTGVK
810 820 830 840 850
SDKLVYVDLL REEADTKTDA GAPKAGLVAE NVGQDTEATK PSADPVIQQR
860 870 880 890 900
REFISLREEL GRITDFHESF TFKQASSQPV FSLGKDSGAA GTNKENLGVQ
910 920 930 940 950
VATPFLETAL GSEGPAVTFG KTQEDPKPFC VGGAPPNMDV TPAYTKEGTD
960 970 980 990 1000
EAESNDGKVL KPKPSKLAKR IANSAGYVGD RFKCVTTELY ADSSQLSREQ
1010 1020 1030 1040 1050
RALQMEGLQE DSILCLPAAY CERAMMRFSE LEMKEREGSH PATKDSEVCK
1060 1070 1080 1090 1100
FSPADWERLK GNQEKKPKSV TLEEAIADQN DSERCEYSTG NKHDLFEAPE
1110 1120 1130 1140 1150
DKDLPVEKYF LERPPVSEPP SDQGVVDTPH SPTLRLDRKR KLSGDSTHTE
1160 1170 1180 1190 1200
TAVEELAEDP LKAKRRRISK DDWPEREMTN SSSNHLEDPH CNELTNLKVC
1210 1220 1230 1240 1250
IELTGLHPKK QRHLLHLRER WEQQVSAAES KPGRQSRKEV AQAVQPEVTS
1260 1270 1280 1290 1300
QGTNITEEKP GRKKAEAKGN RGWSEESLKS CDNEQGLPVL SGSPPMKSLS
1310 1320 1330 1340 1350
STNASGKKQT QPSCTPASRL PAKQQKIKES QKTDVLCTGE DEDCQAASPL
1360 1370 1380 1390 1400
QKYTDNIEKP SGKRLCKTKH LIPQESRRSL QITGDYYVEN TDTKMTVRRF
1410 1420 1430 1440 1450
RKRPEPSSDY DLSPPAKQEP KPFDRLQQLL PATQATQLPR SNSPQETTQS
1460 1470 1480 1490 1500
RPMPPEARRL IVNKNAGETL LQRAARLGYE EVVLYCLENK VCDVNHRDNA
1510 1520 1530 1540 1550
GYCALHEACA RGWLNIVRHL LEYGADVNCS AQDGTRPLHD AVENDHLEIV
1560 1570 1580 1590 1600
RLLLSYGADP TLATYSGRTI MKMTHSELME KFLTDYLNDL QGRSEDDTSG
1610 1620 1630 1640 1650
AWEFYGSSVC EPDDESGYDV LANPPGPEDP DEEEDTYSDL FEFEFAESSL
1660 1670 1680 1690 1700
LPCYNIQVSV AQGPRNWLLL SDVLKKLKMS SRIFRSNFPN LEIVTIAEAE
1710 1720 1730 1740 1750
FYRQVSTSLL FSCPKDLEAF NPESKELLDL VEFTNELQTL LGSSVEWLHP

SDTGHENYW
Length:1,759
Mass (Da):192,631
Last modified:January 4, 2005 - v2
Checksum:iC7FF21CFB3C60D49
GO
Isoform 2 (identifier: Q8CGN4-2) [UniParc]FASTAAdd to basket

Also known as: B

The sequence of this isoform differs from the canonical sequence as follows:
     1005-1022: Missing.

Show »
Length:1,741
Mass (Da):190,664
Checksum:i6356F262D31FEB72
GO
Isoform 3 (identifier: Q8CGN4-3) [UniParc]FASTAAdd to basket

Also known as: C

The sequence of this isoform differs from the canonical sequence as follows:
     1171-1204: Missing.

Show »
Length:1,725
Mass (Da):188,678
Checksum:iBC1E474B524049F6
GO
Isoform 4 (identifier: Q8CGN4-4) [UniParc]FASTAAdd to basket

Also known as: D

The sequence of this isoform differs from the canonical sequence as follows:
     1005-1022: Missing.
     1171-1204: Missing.

Show »
Length:1,707
Mass (Da):186,710
Checksum:iEEDAB60D370F5520
GO

Sequence cautioni

The sequence BAC98208.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti161 – 1611A → V in AAN85318 (PubMed:12776190).Curated
Sequence conflicti161 – 1611A → V in AAN85319 (PubMed:12776190).Curated
Sequence conflicti161 – 1611A → V in AAN85320 (PubMed:12776190).Curated
Sequence conflicti161 – 1611A → V in AAN85321 (PubMed:12776190).Curated
Sequence conflicti167 – 1671G → S in AAN85318 (PubMed:12776190).Curated
Sequence conflicti167 – 1671G → S in AAN85319 (PubMed:12776190).Curated
Sequence conflicti167 – 1671G → S in AAN85320 (PubMed:12776190).Curated
Sequence conflicti167 – 1671G → S in AAN85321 (PubMed:12776190).Curated
Sequence conflicti731 – 7311I → V in AAN85318 (PubMed:12776190).Curated
Sequence conflicti731 – 7311I → V in AAN85319 (PubMed:12776190).Curated
Sequence conflicti731 – 7311I → V in AAN85320 (PubMed:12776190).Curated
Sequence conflicti731 – 7311I → V in AAN85321 (PubMed:12776190).Curated
Sequence conflicti852 – 8521E → D in BAC35338 (PubMed:16141072).Curated
Sequence conflicti1424 – 14241D → G in AAN85318 (PubMed:12776190).Curated
Sequence conflicti1424 – 14241D → G in AAN85319 (PubMed:12776190).Curated
Sequence conflicti1424 – 14241D → G in AAN85320 (PubMed:12776190).Curated
Sequence conflicti1424 – 14241D → G in AAN85321 (PubMed:12776190).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1005 – 102218Missing in isoform 2 and isoform 4. 2 PublicationsVSP_012558Add
BLAST
Alternative sequencei1171 – 120434Missing in isoform 3 and isoform 4. 3 PublicationsVSP_012559Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY161170 mRNA. Translation: AAN85318.1.
AY161171 mRNA. Translation: AAN85319.1.
AY161172 mRNA. Translation: AAN85320.1.
AY161173 mRNA. Translation: AAN85321.1.
AK129398 mRNA. Translation: BAC98208.1. Different initiation.
AL808012 Genomic DNA. Translation: CAM24722.1.
AL808012 Genomic DNA. Translation: CAM24723.1.
AL808012 Genomic DNA. Translation: CAM24724.1.
AL808012 Genomic DNA. Translation: CAM24725.1.
BC058656 mRNA. Translation: AAH58656.1.
AK053309 mRNA. Translation: BAC35338.1.
CCDSiCCDS30021.1. [Q8CGN4-3]
CCDS30022.1. [Q8CGN4-4]
CCDS40872.1. [Q8CGN4-2]
CCDS40873.1. [Q8CGN4-1]
RefSeqiNP_001161793.1. NM_001168321.1. [Q8CGN4-4]
NP_083786.2. NM_029510.3. [Q8CGN4-1]
NP_778209.2. NM_175044.3. [Q8CGN4-2]
NP_778210.2. NM_175045.3. [Q8CGN4-3]
NP_778211.2. NM_175046.3. [Q8CGN4-4]
UniGeneiMm.196328.

Genome annotation databases

EnsembliENSMUST00000043441; ENSMUSP00000048024; ENSMUSG00000040363. [Q8CGN4-4]
ENSMUST00000065143; ENSMUSP00000068618; ENSMUSG00000040363. [Q8CGN4-3]
ENSMUST00000115512; ENSMUSP00000111174; ENSMUSG00000040363. [Q8CGN4-2]
ENSMUST00000115513; ENSMUSP00000111175; ENSMUSG00000040363. [Q8CGN4-1]
ENSMUST00000124033; ENSMUSP00000116258; ENSMUSG00000040363. [Q8CGN4-4]
GeneIDi71458.
KEGGimmu:71458.
UCSCiuc009sqq.2. mouse. [Q8CGN4-1]
uc009sqr.2. mouse. [Q8CGN4-3]
uc009sqs.2. mouse. [Q8CGN4-2]
uc009sqt.2. mouse. [Q8CGN4-4]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY161170 mRNA. Translation: AAN85318.1.
AY161171 mRNA. Translation: AAN85319.1.
AY161172 mRNA. Translation: AAN85320.1.
AY161173 mRNA. Translation: AAN85321.1.
AK129398 mRNA. Translation: BAC98208.1. Different initiation.
AL808012 Genomic DNA. Translation: CAM24722.1.
AL808012 Genomic DNA. Translation: CAM24723.1.
AL808012 Genomic DNA. Translation: CAM24724.1.
AL808012 Genomic DNA. Translation: CAM24725.1.
BC058656 mRNA. Translation: AAH58656.1.
AK053309 mRNA. Translation: BAC35338.1.
CCDSiCCDS30021.1. [Q8CGN4-3]
CCDS30022.1. [Q8CGN4-4]
CCDS40872.1. [Q8CGN4-2]
CCDS40873.1. [Q8CGN4-1]
RefSeqiNP_001161793.1. NM_001168321.1. [Q8CGN4-4]
NP_083786.2. NM_029510.3. [Q8CGN4-1]
NP_778209.2. NM_175044.3. [Q8CGN4-2]
NP_778210.2. NM_175045.3. [Q8CGN4-3]
NP_778211.2. NM_175046.3. [Q8CGN4-4]
UniGeneiMm.196328.

3D structure databases

ProteinModelPortaliQ8CGN4.
SMRiQ8CGN4. Positions 1467-1583, 1640-1752.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi214722. 8 interactions.
DIPiDIP-29852N.
IntActiQ8CGN4. 3 interactions.

PTM databases

PhosphoSiteiQ8CGN4.

Proteomic databases

MaxQBiQ8CGN4.
PaxDbiQ8CGN4.
PRIDEiQ8CGN4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000043441; ENSMUSP00000048024; ENSMUSG00000040363. [Q8CGN4-4]
ENSMUST00000065143; ENSMUSP00000068618; ENSMUSG00000040363. [Q8CGN4-3]
ENSMUST00000115512; ENSMUSP00000111174; ENSMUSG00000040363. [Q8CGN4-2]
ENSMUST00000115513; ENSMUSP00000111175; ENSMUSG00000040363. [Q8CGN4-1]
ENSMUST00000124033; ENSMUSP00000116258; ENSMUSG00000040363. [Q8CGN4-4]
GeneIDi71458.
KEGGimmu:71458.
UCSCiuc009sqq.2. mouse. [Q8CGN4-1]
uc009sqr.2. mouse. [Q8CGN4-3]
uc009sqs.2. mouse. [Q8CGN4-2]
uc009sqt.2. mouse. [Q8CGN4-4]

Organism-specific databases

CTDi54880.
MGIiMGI:1918708. Bcor.
RougeiSearch...

Phylogenomic databases

eggNOGiCOG0666.
GeneTreeiENSGT00760000119090.
HOVERGENiHBG050682.
InParanoidiQ8CGN4.
OMAiSSCPRMG.
OrthoDBiEOG7KWSGQ.
PhylomeDBiQ8CGN4.
TreeFamiTF333317.

Miscellaneous databases

ChiTaRSiBcor. mouse.
NextBioi333823.
PROiQ8CGN4.
SOURCEiSearch...

Gene expression databases

BgeeiQ8CGN4.
CleanExiMM_BCOR.
ExpressionAtlasiQ8CGN4. baseline and differential.
GenevestigatoriQ8CGN4.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor."
    Srinivasan R.S., de Erkenez A.C., Hemenway C.S.
    Oncogene 22:3395-3406(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4), FUNCTION, INTERACTION WITH MLLT3, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Strain: Swiss Webster / NIH.
  2. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
    DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Tissue: Embryonic tail.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Strain: C57BL/6.
    Tissue: Brain.
  5. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-945.
    Strain: C57BL/6J.
    Tissue: Eye.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiBCOR_MOUSE
AccessioniPrimary (citable) accession number: Q8CGN4
Secondary accession number(s): B1AXK3
, B1AXK4, B1AXK5, B1AXK6, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: January 4, 2005
Last modified: March 4, 2015
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.