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Protein
Submitted name:

Ift74 protein

Gene

Ift74

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. beta-tubulin binding Source: MGI
  2. chromatin binding Source: MGI

GO - Biological processi

  1. cilium assembly Source: MGI
  2. cilium morphogenesis Source: MGI
  3. epidermis development Source: MGI
  4. intraciliary transport Source: GO_Central
  5. intraciliary transport involved in cilium morphogenesis Source: MGI
  6. keratinocyte development Source: MGI
  7. negative regulation of epithelial cell proliferation Source: MGI
  8. Notch signaling pathway Source: MGI
  9. positive regulation of cell adhesion mediated by integrin Source: MGI
  10. positive regulation of transcription from RNA polymerase II promoter Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ift74 proteinImported
Gene namesi
Name:Ift74Imported
Synonyms:Ccdc2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1914944. Ift74.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: MGI
  2. cilium Source: MGI
  3. intraciliary transport particle B Source: MGI
  4. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8CGJ7.

Structurei

3D structure databases

ProteinModelPortaliQ8CGJ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG050820.

Family and domain databases

InterProiIPR029602. IFT74.
[Graphical view]
PANTHERiPTHR31432:SF0. PTHR31432:SF0. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8CGJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNHKSSAP RPISRGGIGL TGRPPSGIRP PSGNVRVATA MPPTTARPGS
60 70 80 90 100
RGGPLGTGGV LSSQIKVADR PVTQQGLSGM KTGMKGPQRQ ILDKSYYLGL
110 120 130 140 150
LRSKISELTT EINKLQKEIE MYNQENSVYL SYEKRAETLA VEIKDFQGQL
160 170 180 190 200
ADYNMLVDKL NTNTEMEEVM SDYNMLKAQN DRETQSMDVI FTERQAKEKQ
210 220 230 240 250
IRSVEEEVEQ EKQAADGIIK NMSPEKQVKY IEMKTTNEKL LQELDTLQQQ
260 270 280 290 300
LDSLNMKKES LETEIAHSQV KQEAVLLYEK LYELESHRDQ MIAEDKSMGS
310 320 330
PMEERERLLK QVKEDNQEIA SMERQLTDIK KKK
Length:333
Mass (Da):37,715
Last modified:February 28, 2003 - v1
Checksum:iC63E53CF71927255
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei333 – 3331Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023760 mRNA. Translation: AAH23760.1.
UniGeneiMm.240619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023760 mRNA. Translation: AAH23760.1.
UniGeneiMm.240619.

3D structure databases

ProteinModelPortaliQ8CGJ7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1914944. Ift74.

Phylogenomic databases

HOVERGENiHBG050820.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

GenevestigatoriQ8CGJ7.

Family and domain databases

InterProiIPR029602. IFT74.
[Graphical view]
PANTHERiPTHR31432:SF0. PTHR31432:SF0. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: Mammary tumor. C3Imported.

Entry informationi

Entry nameiQ8CGJ7_MOUSE
AccessioniPrimary (citable) accession number: Q8CGJ7
Entry historyi
Integrated into UniProtKB/TrEMBL: February 28, 2003
Last sequence update: February 28, 2003
Last modified: February 3, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.