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Q8CGH8

- Q8CGH8_MOUSE

UniProt

Q8CGH8 - Q8CGH8_MOUSE

Protein
Submitted name:

Pdgfra protein

Gene

Pdgfra

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. platelet-derived growth factor alpha-receptor activity Source: InterPro
    2. platelet-derived growth factor binding Source: MGI

    GO - Biological processi

    1. adrenal gland development Source: MGI
    2. anatomical structure morphogenesis Source: MGI
    3. cellular response to amino acid stimulus Source: MGI
    4. estrogen metabolic process Source: MGI
    5. extracellular matrix organization Source: MGI
    6. face morphogenesis Source: MGI
    7. female gonad development Source: MGI
    8. hematopoietic progenitor cell differentiation Source: MGI
    9. in utero embryonic development Source: MGI
    10. Leydig cell differentiation Source: MGI
    11. lung development Source: MGI
    12. luteinization Source: MGI
    13. male genitalia development Source: MGI
    14. odontogenesis of dentin-containing tooth Source: MGI
    15. organ morphogenesis Source: MGI
    16. palate development Source: MGI
    17. platelet-derived growth factor receptor signaling pathway Source: MGI
    18. signal transduction involved in regulation of gene expression Source: MGI
    19. skeletal system morphogenesis Source: MGI

    Protein family/group databases

    MEROPSiI43.001.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Pdgfra proteinImported
    Gene namesi
    Name:PdgfraImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:97530. Pdgfra.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. external side of plasma membrane Source: MGI
    3. microvillus Source: MGI
    4. nucleus Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ8CGH8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CGH8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG004335.
    InParanoidiQ8CGH8.

    Family and domain databases

    Gene3Di2.60.40.10. 4 hits.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR003598. Ig_sub2.
    IPR027290. PDGFRA.
    [Graphical view]
    PANTHERiPTHR24416:SF52. PTHR24416:SF52. 1 hit.
    PfamiPF07679. I-set. 1 hit.
    [Graphical view]
    SMARTiSM00409. IG. 2 hits.
    SM00408. IGc2. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8CGH8-1 [UniParc]FASTAAdd to Basket

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    MGTSHQVFLV LSCLLTGPGL ISCQLLLPSI LPNENEKIVQ LNSSFSLRCV    50
    GESEVSWQHP MSEEDDPNVE IRSEENNSGL FVTVLEVVNA SAAHTGWYTC 100
    YYNHTQTDES EIEGRHIYIY VPDPDMAFVP LGMTDSLVIV EEDDSAIIPC 150
    RTTDPETQVT LHNNGRLVPA SYDSRQGFNG TFSVGPYICE ATVKGRTFKT 200
    SEFNVYALKA TSELNLEMDA RQTVYKAGET IVVTCAVFNN EVVDLQWTYP 250
    GEVRNKGITM LEEIKLPSIK LVYTLTVPKA TVKDSGEYEC AARQATKEVK 300
    EMKRVTISVH EKGFVEIEPT FGQLEAVNLH EVREFVVEVQ AYPTPRISWL 350
    KDNLTLIENL TEITTDVQKS QETRYQSKLK LIRAKEEDSG HYTIIVQNED 400
    DVKSYTFELS TLVPASILDL VDDHHGSGGG QTVRCTAEGT PLPEIDWMIC 450
    KHIKKYGNQM FPVLVWSGCF FHDIKGLKCS LKKKKK 486
    Length:486
    Mass (Da):54,569
    Last modified:March 1, 2003 - v1
    Checksum:i2BA1DE55490720B6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei486 – 4861Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC037467 mRNA. Translation: AAH37467.1.
    UniGeneiMm.221403.

    Genome annotation databases

    UCSCiuc008xua.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC037467 mRNA. Translation: AAH37467.1 .
    UniGenei Mm.221403.

    3D structure databases

    ProteinModelPortali Q8CGH8.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I43.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc008xua.1. mouse.

    Organism-specific databases

    MGIi MGI:97530. Pdgfra.

    Phylogenomic databases

    HOVERGENi HBG004335.
    InParanoidi Q8CGH8.

    Miscellaneous databases

    ChiTaRSi PDGFRA. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8CGH8.

    Family and domain databases

    Gene3Di 2.60.40.10. 4 hits.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003599. Ig_sub.
    IPR003598. Ig_sub2.
    IPR027290. PDGFRA.
    [Graphical view ]
    PANTHERi PTHR24416:SF52. PTHR24416:SF52. 1 hit.
    Pfami PF07679. I-set. 1 hit.
    [Graphical view ]
    SMARTi SM00409. IG. 2 hits.
    SM00408. IGc2. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: ColonImported.

    Entry informationi

    Entry nameiQ8CGH8_MOUSE
    AccessioniPrimary (citable) accession number: Q8CGH8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)