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Q8CGH8 (Q8CGH8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Pdgfra protein EMBL AAH37467.1
Gene names
Name:Pdgfra EMBL AAH37467.1 MGI 97530
OrganismMus musculus (Mouse) EMBL AAH37467.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length486 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   DomainRepeat SAAS SAAS013098
Gene Ontology (GO)
   Biological_processLeydig cell differentiation

Inferred from mutant phenotype PubMed 19056881. Source: MGI

adrenal gland development

Inferred from genetic interaction PubMed 19056881. Source: MGI

cellular response to amino acid stimulus

Inferred from direct assay PubMed 20548288. Source: MGI

estrogen metabolic process

Inferred from genetic interaction PubMed 19056881. Source: MGI

extracellular matrix organization

Inferred from mutant phenotype PubMed 15543606. Source: MGI

face morphogenesis

Inferred from mutant phenotype PubMed 17143286. Source: MGI

in utero embryonic development

Inferred from mutant phenotype PubMed 10331973PubMed 17143286. Source: MGI

lung development

Inferred from mutant phenotype PubMed 11803579. Source: MGI

luteinization

Inferred from mutant phenotype PubMed 19056881. Source: MGI

male genitalia development

Inferred from mutant phenotype PubMed 12651897. Source: MGI

odontogenesis of dentin-containing tooth

Inferred from mutant phenotype PubMed 15543606. Source: MGI

palate development

Inferred from mutant phenotype PubMed 17143286. Source: MGI

platelet-derived growth factor receptor signaling pathway

Inferred from mutant phenotype PubMed 17143286. Source: MGI

signal transduction involved in regulation of gene expression

Inferred from direct assay PubMed 18462699. Source: MGI

skeletal system morphogenesis

Inferred from mutant phenotype PubMed 17143286. Source: MGI

vascular endothelial growth factor receptor signaling pathway

Inferred from electronic annotation. Source: InterPro

vascular endothelial growth factor signaling pathway

Inferred from electronic annotation. Source: GOC

   Cellular_componentcytoplasm

Inferred from direct assay PubMed 22027834. Source: MGI

external side of plasma membrane

Inferred from direct assay PubMed 17350578. Source: MGI

integral to plasma membrane

Inferred from electronic annotation. Source: InterPro

nucleus

Inferred from direct assay PubMed 21146513. Source: MGI

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

platelet-derived growth factor binding

Inferred from direct assay PubMed 15372073. Source: MGI

vascular endothelial growth factor-activated receptor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue4861 EMBL AAH37467.1

Sequences

Sequence LengthMass (Da)Tools
Q8CGH8 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 2BA1DE55490720B6

FASTA48654,569
        10         20         30         40         50         60 
MGTSHQVFLV LSCLLTGPGL ISCQLLLPSI LPNENEKIVQ LNSSFSLRCV GESEVSWQHP 

        70         80         90        100        110        120 
MSEEDDPNVE IRSEENNSGL FVTVLEVVNA SAAHTGWYTC YYNHTQTDES EIEGRHIYIY 

       130        140        150        160        170        180 
VPDPDMAFVP LGMTDSLVIV EEDDSAIIPC RTTDPETQVT LHNNGRLVPA SYDSRQGFNG 

       190        200        210        220        230        240 
TFSVGPYICE ATVKGRTFKT SEFNVYALKA TSELNLEMDA RQTVYKAGET IVVTCAVFNN 

       250        260        270        280        290        300 
EVVDLQWTYP GEVRNKGITM LEEIKLPSIK LVYTLTVPKA TVKDSGEYEC AARQATKEVK 

       310        320        330        340        350        360 
EMKRVTISVH EKGFVEIEPT FGQLEAVNLH EVREFVVEVQ AYPTPRISWL KDNLTLIENL 

       370        380        390        400        410        420 
TEITTDVQKS QETRYQSKLK LIRAKEEDSG HYTIIVQNED DVKSYTFELS TLVPASILDL 

       430        440        450        460        470        480 
VDDHHGSGGG QTVRCTAEGT PLPEIDWMIC KHIKKYGNQM FPVLVWSGCF FHDIKGLKCS 


LKKKKK

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N EMBL AAH37467.1.
Tissue: Colon EMBL AAH37467.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC037467 mRNA. Translation: AAH37467.1.
IPIIPI00985588.
UniGeneMm.221403.

3D structure databases

HSSPHSSP built from PDB template 1QSV based on UniProtKB P17948.
ProteinModelPortalQ8CGH8.
ModBaseSearch...

Protein family/group databases

MEROPSI43.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc008xua.1. mouse.

Organism-specific databases

MGIMGI:97530. Pdgfra.

Phylogenomic databases

HOVERGENHBG004335.
InParanoidQ8CGH8.

Gene expression databases

GenevestigatorQ8CGH8.

Family and domain databases

Gene3D2.60.40.10. 4 hits.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR009134. Tyr_kinase_VEGFR_rcpt_N.
[Graphical view]
PfamPF07679. I-set. 2 hits.
[Graphical view]
PRINTSPR01832. VEGFRECEPTOR.
SMARTSM00409. IG. 2 hits.
SM00408. IGc2. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPDGFRA. mouse.
SOURCESearch...

Entry information

Entry nameQ8CGH8_MOUSE
AccessionPrimary (citable) accession number: Q8CGH8
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 3, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info