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Q8CGH8

- Q8CGH8_MOUSE

UniProt

Q8CGH8 - Q8CGH8_MOUSE

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Protein
Submitted name:

Pdgfra protein

Gene

Pdgfra

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. platelet-derived growth factor alpha-receptor activity Source: InterPro
  2. platelet-derived growth factor binding Source: MGI

GO - Biological processi

  1. adrenal gland development Source: MGI
  2. anatomical structure morphogenesis Source: MGI
  3. cellular response to amino acid stimulus Source: MGI
  4. estrogen metabolic process Source: MGI
  5. extracellular matrix organization Source: MGI
  6. face morphogenesis Source: MGI
  7. female gonad development Source: MGI
  8. hematopoietic progenitor cell differentiation Source: MGI
  9. in utero embryonic development Source: MGI
  10. Leydig cell differentiation Source: MGI
  11. lung development Source: MGI
  12. luteinization Source: MGI
  13. male genitalia development Source: MGI
  14. odontogenesis of dentin-containing tooth Source: MGI
  15. organ morphogenesis Source: MGI
  16. palate development Source: MGI
  17. platelet-derived growth factor receptor signaling pathway Source: MGI
  18. signal transduction involved in regulation of gene expression Source: MGI
  19. skeletal system morphogenesis Source: MGI
Complete GO annotation...

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Pdgfra proteinImported
Gene namesi
Name:PdgfraImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97530. Pdgfra.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. external side of plasma membrane Source: MGI
  3. microvillus Source: MGI
  4. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8CGH8.

Structurei

3D structure databases

ProteinModelPortaliQ8CGH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004335.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR027290. PDGFRA.
[Graphical view]
PANTHERiPTHR24416:SF52. PTHR24416:SF52. 1 hit.
PfamiPF07679. I-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00408. IGc2. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8CGH8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGTSHQVFLV LSCLLTGPGL ISCQLLLPSI LPNENEKIVQ LNSSFSLRCV
60 70 80 90 100
GESEVSWQHP MSEEDDPNVE IRSEENNSGL FVTVLEVVNA SAAHTGWYTC
110 120 130 140 150
YYNHTQTDES EIEGRHIYIY VPDPDMAFVP LGMTDSLVIV EEDDSAIIPC
160 170 180 190 200
RTTDPETQVT LHNNGRLVPA SYDSRQGFNG TFSVGPYICE ATVKGRTFKT
210 220 230 240 250
SEFNVYALKA TSELNLEMDA RQTVYKAGET IVVTCAVFNN EVVDLQWTYP
260 270 280 290 300
GEVRNKGITM LEEIKLPSIK LVYTLTVPKA TVKDSGEYEC AARQATKEVK
310 320 330 340 350
EMKRVTISVH EKGFVEIEPT FGQLEAVNLH EVREFVVEVQ AYPTPRISWL
360 370 380 390 400
KDNLTLIENL TEITTDVQKS QETRYQSKLK LIRAKEEDSG HYTIIVQNED
410 420 430 440 450
DVKSYTFELS TLVPASILDL VDDHHGSGGG QTVRCTAEGT PLPEIDWMIC
460 470 480
KHIKKYGNQM FPVLVWSGCF FHDIKGLKCS LKKKKK
Length:486
Mass (Da):54,569
Last modified:March 1, 2003 - v1
Checksum:i2BA1DE55490720B6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei486 – 4861Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC037467 mRNA. Translation: AAH37467.1.
UniGeneiMm.221403.

Genome annotation databases

UCSCiuc008xua.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC037467 mRNA. Translation: AAH37467.1 .
UniGenei Mm.221403.

3D structure databases

ProteinModelPortali Q8CGH8.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I43.001.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc008xua.1. mouse.

Organism-specific databases

MGIi MGI:97530. Pdgfra.

Phylogenomic databases

HOVERGENi HBG004335.

Miscellaneous databases

ChiTaRSi PDGFRA. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8CGH8.

Family and domain databases

Gene3Di 2.60.40.10. 4 hits.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR027290. PDGFRA.
[Graphical view ]
PANTHERi PTHR24416:SF52. PTHR24416:SF52. 1 hit.
Pfami PF07679. I-set. 1 hit.
[Graphical view ]
SMARTi SM00409. IG. 2 hits.
SM00408. IGc2. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: ColonImported.

Entry informationi

Entry nameiQ8CGH8_MOUSE
AccessioniPrimary (citable) accession number: Q8CGH8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)