Q8CFT3 (Q8CFT3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nerve growth factor receptor (TNFR superfamily, member 16) EMBL AAH38365.1

Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000000122

Gene names

Name:	Ngfr EMBL AAH38365.1 Ensembl ENSMUSP00000000122 MGI 97323
ORF Names:	RP23-67E18.6-001 EMBL CAI25975.1

Organism

Mus musculus (Mouse) EMBL AAH38365.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	427 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL AAH38365.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	axon guidance Inferred from mutant phenotype. Source: MGI central nervous system development Inferred from mutant phenotype. Source: MGI detection of temperature stimulus Inferred from mutant phenotype. Source: MGI hair follicle morphogenesis Inferred from mutant phenotype. Source: MGI induction of apoptosis Inferred from direct assay. Source: MGI negative regulation of fibroblast growth factor receptor signaling pathway Inferred from mutant phenotype. Source: MGI negative regulation of hair follicle development Inferred from mutant phenotype. Source: MGI nerve development Inferred from mutant phenotype. Source: MGI positive regulation of fibroblast proliferation Inferred from mutant phenotype. Source: MGI positive regulation of odontogenesis of dentin-containing tooth Inferred from mutant phenotype. Source: MGI regulation of gene expression Inferred from mutant phenotype. Source: MGI skin development Inferred from mutant phenotype. Source: MGI
Cellular component	plasma membrane Inferred from direct assay. Source: MGI
Molecular function	death receptor activity Inferred from direct assay. Source: MGI nerve growth factor binding Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8CFT3 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 7AC73263F7B31436	FASTA	427	45,647
	10 20 30 40 50 60 MRRAGAACSA MDRLRLLLLL LLLLGVSFGG AKETCSTGMY THSGECCKAC NLGEGVAQPC 70 80 90 100 110 120 GANQTVCEPC LDSVTFSDVV SATEPCKPCT ECLGLQSMSA PCVEADDAVC RCSYGYYQDE 130 140 150 160 170 180 ETGRCEACSV CGVGSGLVFS CQDKQNTVCE ECPEGTYSDE ANHVDPCLPC TVCEDTERQL 190 200 210 220 230 240 RECTPWADAE CEEIPGRWIT RSTPPEGSDV TTPSTQEPEA PPERDLIAST VADTVTTVMG 250 260 270 280 290 300 SSQPVVTRGT ADNLIPVYCS ILAAVVVGLV AYIAFKRWNS CKQNKQGANS RPVNQTPPPE 310 320 330 340 350 360 GEKLHSDSGI SVDSQSLHDQ QTHTQTASGQ ALKGDGNLYS SLPLTKREEV EKLLNGDTWR 370 380 390 400 410 420 HLAGELGYQP EHIDSFTHEA CPVRALLASW GAQDSATLDA LLAALRRIQR ADIVESLCSE STATSPV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000000122.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Eye EMBL AAH38365.1.
[3]	Lovell J. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000000122.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC038365 mRNA. Translation: AAH38365.1. AL662875 Genomic DNA. Translation: CAI25975.1.
IPI	IPI00407509.
RefSeq	NP_150086.2. NM_033217.3.
UniGene	Mm.283893.
3D structure databases
HSSP	HSSP built from PDB template 1NGR based on UniProtKB P07174.
ProteinModelPortal	Q8CFT3.
SMR	Q8CFT3. Positions 34-192, 336-420.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8CFT3.
Proteomic databases
PRIDE	Q8CFT3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000000122; ENSMUSP00000000122; ENSMUSG00000000120.
GeneID	18053.
KEGG	mmu:18053.
UCSC	uc007lam.1. mouse.
Organism-specific databases
CTD	4804.
MGI	MGI:97323. Ngfr.
Phylogenomic databases
HOGENOM	HBG715212.
HOVERGEN	HBG060431.
InParanoid	Q8CFT3.
OMA	FSCQDKQ.
PhylomeDB	Q8CFT3.
Gene expression databases
ArrayExpress	Q8CFT3.
Bgee	Q8CFT3.
Genevestigator	Q8CFT3.
Family and domain databases
InterPro	IPR000488. Death. IPR011029. DEATH-like. IPR022325. TNFR_16. IPR001368. TNFR_Cys_rich_reg. [Graphical view]
Gene3D	G3DSA:1.10.533.10. DEATH_like. 1 hit.
KO	K02583.
Pfam	PF00531. Death. 1 hit. PF00020. TNFR_c6. 3 hits. [Graphical view]
PRINTS	PR01966. TNFACTORR16.
SMART	SM00005. DEATH. 1 hit. SM00208. TNFR. 4 hits. [Graphical view]
SUPFAM	SSF47986. DEATH_like. 1 hit.
PROSITE	PS50017. DEATH_DOMAIN. 1 hit. PS00652. TNFR_NGFR_1. 3 hits. PS50050. TNFR_NGFR_2. 4 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	293183.
PMAP-CutDB	Q8CFT3.
SOURCE	Search...

Entry information

Entry name

Q8CFT3_MOUSE

Accession

Primary (citable) accession number: Q8CFT3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 16, 2011
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)