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Protein
Submitted name:

Proviral integration site 1

Gene

Pim1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei67ATPUniRule annotation1
Binding sitei121ATP; via carbonyl oxygenUniRule annotation1
Binding sitei128ATPUniRule annotation1
Active sitei167Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Proviral integration site 1Imported
Submitted name:
Serine/threonine-protein kinase pim-1Imported
Gene namesi
Name:Pim1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:97584. Pim1.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000024014.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 290Protein kinaseInterPro annotationAdd BLAST253

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0583. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00760000119045.
HOVERGENiHBG106681.
KOiK04702.
OMAiCQHLIKW.
OrthoDBiEOG091G0IMW.
TreeFamiTF320810.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR017348. PIM1/2/3.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
PIRSFiPIRSF037993. STPK_Pim-1. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CFN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG
60 70 80 90 100
SVYSGIRVAD NLPVAIKHVE KDRISDWGEL PNGTRVPMEV VLLKKVSSDF
110 120 130 140 150
SGVIRLLDWF ERPDSFVLIL ERPEPVQDLF DFITERGALQ EDLARGFFWQ
160 170 180 190 200
VLEAVRHCHN CGVLHRDIKD ENILIDLSRG EIKLIDFGSG ALLKDTVYTD
210 220 230 240 250
FDGTRVYSPP EWIRYHRYHG RSAAVWSLGI LLYDMVCGDI PFEHDEEIIK
260 270 280 290 300
GQVFFRQTVS SECQHLIKWC LSLRPSDRPS FEEIRNHPWM QGDLLPQAAS
310
EIHLHSLSPG SSK
Length:313
Mass (Da):35,451
Last modified:March 1, 2003 - v1
Checksum:i1294F16A03B7C7D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC163629 Genomic DNA. No translation available.
BC042885 mRNA. Translation: AAH42885.1.
BC053019 mRNA. Translation: AAH53019.1.
BC055316 mRNA. Translation: AAH55316.1.
RefSeqiNP_032868.2. NM_008842.3.
UniGeneiMm.405293.
Mm.485038.

Genome annotation databases

EnsembliENSMUST00000024811; ENSMUSP00000024811; ENSMUSG00000024014.
GeneIDi18712.
KEGGimmu:18712.
UCSCiuc008bsz.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8CFN8_MOUSE
AccessioniPrimary (citable) accession number: Q8CFN8
Secondary accession number(s): F6XDQ5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: August 30, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported