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Protein

Sorting nexin-30

Gene

Snx30

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in several stages of intracellular trafficking.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sorting nexin-30
Gene namesi
Name:Snx30
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2443882 Snx30

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002845341 – 437Sorting nexin-30Add BLAST437

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei38PhosphothreonineCombined sources1
Modified residuei40PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8CE50
PaxDbiQ8CE50
PeptideAtlasiQ8CE50
PRIDEiQ8CE50

PTM databases

iPTMnetiQ8CE50
PhosphoSitePlusiQ8CE50

Expressioni

Gene expression databases

BgeeiENSMUSG00000028385
CleanExiMM_SNX30
GenevisibleiQ8CE50 MM

Interactioni

Protein-protein interaction databases

IntActiQ8CE50, 1 interactor
MINTiQ8CE50
STRINGi10090.ENSMUSP00000030080

Structurei

3D structure databases

ProteinModelPortaliQ8CE50
SMRiQ8CE50
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini89 – 210PXPROSITE-ProRule annotationAdd BLAST122

Sequence similaritiesi

Belongs to the sorting nexin family.Curated

Phylogenomic databases

eggNOGiKOG2273 Eukaryota
COG5391 LUCA
GeneTreeiENSGT00910000144107
HOGENOMiHOG000010283
HOVERGENiHBG009723
InParanoidiQ8CE50
KOiK17921
OMAiQRMEYVR
OrthoDBiEOG091G08JS
PhylomeDBiQ8CE50
TreeFamiTF328543

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR004148 BAR_dom
IPR001683 Phox
IPR036871 PX_dom_sf
IPR028649 SNX30
PANTHERiPTHR10555:SF123 PTHR10555:SF123, 1 hit
PfamiView protein in Pfam
PF03114 BAR, 1 hit
PF00787 PX, 1 hit
SMARTiView protein in SMART
SM00312 PX, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50195 PX, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CE50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGGPPKALP STGPQSLRDM PHPLAGSSSE EAVGGDSTPS PDLLMARSFG
60 70 80 90 100
DKDLILPNGG TPAGTASPAS SSSLLNRLQL DDDIDGEARD LFVTVDDPKK
110 120 130 140 150
HVCTMETYIT YRITTKSTRV EFDLPEYSVR RRYQDFDWLR NKLEESQPTH
160 170 180 190 200
LIPPLPEKFV VKGVVDRFSE EFVETRRKAL DKFLKRITDH PVLSFNEHFN
210 220 230 240 250
VFLTAKDLNA YKKQGIALLS RVGESVKHVT GGYKLRSRPL EFAAISDYLD
260 270 280 290 300
TFALKLGTID RIAQRIIKEE IEYLVELREY GPVYSTWSAL EGELAEPLEG
310 320 330 340 350
VSACIGNCST ALEELTDDIT EEFLPVLREY VLYSDSMKGV LKKRDQVQAE
360 370 380 390 400
YEAKLEAVAL RKEERPKVPA DVEKCQDRME CFNADLKADM ERWQSNKRHD
410 420 430
FRQLLVGLAD KNIQYYEKCL MAWESIIPLL QEKQETK
Length:437
Mass (Da):49,520
Last modified:March 1, 2003 - v1
Checksum:i52805380D0E0D158
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti19D → G in BAE27911 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029012 mRNA Translation: BAC26242.1
AK147437 mRNA Translation: BAE27911.1
AK165619 mRNA Translation: BAE38299.1
AK170774 mRNA Translation: BAE42020.1
AK170999 mRNA Translation: BAE42170.1
AL831738 Genomic DNA No translation available.
BC099674 mRNA Translation: AAH99674.1
CCDSiCCDS18226.1
RefSeqiNP_766056.1, NM_172468.2
UniGeneiMm.259705
Mm.490979

Genome annotation databases

EnsembliENSMUST00000030080; ENSMUSP00000030080; ENSMUSG00000028385
GeneIDi209131
KEGGimmu:209131
UCSCiuc008tae.1 mouse

Similar proteinsi

Entry informationi

Entry nameiSNX30_MOUSE
AccessioniPrimary (citable) accession number: Q8CE50
Secondary accession number(s): Q3UHE6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health