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Protein

Major facilitator superfamily domain-containing protein 7

Gene

Mfsd7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Protein family/group databases

TCDBi2.A.1.28.2. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Major facilitator superfamily domain-containing protein 7
Gene namesi
Name:Mfsd7
Synonyms:Mfsd7a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:2442629. Mfsd7a.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Transmembranei199 – 219HelicalSequence analysisAdd BLAST21
Transmembranei253 – 273HelicalSequence analysisAdd BLAST21
Transmembranei289 – 309HelicalSequence analysisAdd BLAST21
Transmembranei321 – 341HelicalSequence analysisAdd BLAST21
Transmembranei344 – 364HelicalSequence analysisAdd BLAST21
Transmembranei382 – 402HelicalSequence analysisAdd BLAST21
Transmembranei425 – 445HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002734091 – 516Major facilitator superfamily domain-containing protein 7Add BLAST516

Proteomic databases

PaxDbiQ8CE47.
PRIDEiQ8CE47.

PTM databases

iPTMnetiQ8CE47.
PhosphoSitePlusiQ8CE47.

Expressioni

Gene expression databases

BgeeiENSMUSG00000029490.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031455.

Structurei

3D structure databases

ProteinModelPortaliQ8CE47.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2563. Eukaryota.
ENOG410XSTK. LUCA.
GeneTreeiENSGT00530000062892.
HOGENOMiHOG000251610.
HOVERGENiHBG079844.
InParanoidiQ8CE47.
KOiK12306.
OMAiQILCASG.
OrthoDBiEOG091G0837.
PhylomeDBiQ8CE47.
TreeFamiTF314292.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CE47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGTMDRLED CNSPETSGTA GDALPSPRVY ARRWVFLLVV SLLSCSNAML
60 70 80 90 100
WLSFAPVADT IAQHFFLSMD QVNWLSLIYF VLSIPFGMAA IWVLDSVGLR
110 120 130 140 150
GATILGAWLN FSGSVLRAVP CLPVRIPSPF AFFMSGQSLC ALAQTLVVSS
160 170 180 190 200
PAKLAALWFP EHQRATANMI STMSNPLGLL IANVLSPALV KKADDIPMML
210 220 230 240 250
GIYIGPAALA CLLATVCLWE SVPPTPPSTG AANSTSESFL RGLKLLIQNK
260 270 280 290 300
AYVLLAVCFG GGIGVFSSFS ALLEQILCAS GYSNEFSGLC GALFIVFGIL
310 320 330 340 350
GALLLGLYVD RTKHFTEATK IGLCLTSMTS VAFALVSQLQ GQTLALAAIC
360 370 380 390 400
SLFGLFGFSV APVVMELAVE CSFPVGEGAS AGLIFVLGQA EGMLIMLLLT
410 420 430 440 450
ALTVRRTGPS FSTCQQGEDP LDWTVSLLLL AGLCTLFTCV LVIFFNTPYR
460 470 480 490 500
RLEAESGGSS SPTMCARDPR TVSPTQVPPL ETPGLTPPDE ALKEAPGPAS
510
VSKGHSEWAE TMPRDV
Length:516
Mass (Da):54,646
Last modified:March 1, 2003 - v1
Checksum:iFC00C76F548E9157
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti210A → S in AAH94512 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029021 mRNA. Translation: BAC26248.1.
BC094512 mRNA. Translation: AAH94512.1.
CCDSiCCDS19511.1.
RefSeqiNP_766471.1. NM_172883.2.
UniGeneiMm.106818.

Genome annotation databases

EnsembliENSMUST00000031455; ENSMUSP00000031455; ENSMUSG00000029490.
GeneIDi243197.
KEGGimmu:243197.
UCSCiuc008yoc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029021 mRNA. Translation: BAC26248.1.
BC094512 mRNA. Translation: AAH94512.1.
CCDSiCCDS19511.1.
RefSeqiNP_766471.1. NM_172883.2.
UniGeneiMm.106818.

3D structure databases

ProteinModelPortaliQ8CE47.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031455.

Protein family/group databases

TCDBi2.A.1.28.2. the major facilitator superfamily (mfs).

PTM databases

iPTMnetiQ8CE47.
PhosphoSitePlusiQ8CE47.

Proteomic databases

PaxDbiQ8CE47.
PRIDEiQ8CE47.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000031455; ENSMUSP00000031455; ENSMUSG00000029490.
GeneIDi243197.
KEGGimmu:243197.
UCSCiuc008yoc.1. mouse.

Organism-specific databases

CTDi243197.
MGIiMGI:2442629. Mfsd7a.

Phylogenomic databases

eggNOGiKOG2563. Eukaryota.
ENOG410XSTK. LUCA.
GeneTreeiENSGT00530000062892.
HOGENOMiHOG000251610.
HOVERGENiHBG079844.
InParanoidiQ8CE47.
KOiK12306.
OMAiQILCASG.
OrthoDBiEOG091G0837.
PhylomeDBiQ8CE47.
TreeFamiTF314292.

Miscellaneous databases

PROiQ8CE47.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029490.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMFSD7_MOUSE
AccessioniPrimary (citable) accession number: Q8CE47
Secondary accession number(s): Q505K1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.