Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Calicin

Gene

Ccin

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Possible morphogenetic cytoskeletal element in spermiogenic differentiation.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Calicin
Gene namesi
Name:Ccin
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:3045316 Ccin

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002844321 – 588CalicinAdd BLAST588

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei149PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8CDE2
PRIDEiQ8CDE2

PTM databases

iPTMnetiQ8CDE2
PhosphoSitePlusiQ8CDE2

Expressioni

Gene expression databases

BgeeiENSMUSG00000070999
CleanExiMM_CCIN
ExpressionAtlasiQ8CDE2 baseline and differential
GenevisibleiQ8CDE2 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi243037, 1 interactor
STRINGi10090.ENSMUSP00000092725

Structurei

3D structure databases

ProteinModelPortaliQ8CDE2
SMRiQ8CDE2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 98BTBPROSITE-ProRule annotationAdd BLAST71
Domaini133 – 235BACKAdd BLAST103
Repeati280 – 327Kelch 1Add BLAST48
Repeati328 – 375Kelch 2Add BLAST48
Repeati377 – 423Kelch 3Add BLAST47
Repeati425 – 475Kelch 4Add BLAST51
Repeati476 – 525Kelch 5Add BLAST50
Repeati526 – 580Kelch 6Add BLAST55

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

eggNOGiKOG4441 Eukaryota
ENOG410XNX8 LUCA
GeneTreeiENSGT00800000124141
HOGENOMiHOG000060293
HOVERGENiHBG003874
InParanoidiQ8CDE2
OMAiRCPPVIF
OrthoDBiEOG091G03HW
PhylomeDBiQ8CDE2
TreeFamiTF331981

Family and domain databases

Gene3Di2.120.10.80, 1 hit
InterProiView protein in InterPro
IPR011705 BACK
IPR000210 BTB/POZ_dom
IPR015915 Kelch-typ_b-propeller
IPR006652 Kelch_1
IPR011333 SKP1/BTB/POZ_sf
PfamiView protein in Pfam
PF07707 BACK, 1 hit
PF00651 BTB, 1 hit
PF01344 Kelch_1, 1 hit
SMARTiView protein in SMART
SM00875 BACK, 1 hit
SM00225 BTB, 1 hit
SM00612 Kelch, 3 hits
SUPFAMiSSF117281 SSF117281, 2 hits
SSF54695 SSF54695, 1 hit
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CDE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLEFTEKNY NSFVLQNLNK QRKRKEYWDM ALTVDHHVFF AHRNVLAAVS
60 70 80 90 100
PLVKSLISSN DMKTTDELYI TIDPNYLSPA TVDQLLDYFY SGKVVISEQN
110 120 130 140 150
VEELLRGAQY FNTPRLRIHC NDFLIKSIRR VNCLRYLFLA ELFELKEVSD
160 170 180 190 200
LAYSGIRDNF HFWASPEGSM HFMRCPPVIF GRLLRDENLH VLNEDQALSA
210 220 230 240 250
LISWVYFRKE EREKYFKKFF NYINLNAVSN KTLMFASNKL VGLENNSAHA
260 270 280 290 300
TLIESVLMDR KQERPCSLLS YQRKGALLDS VVILGGQKAH GKFNDGVFAY
310 320 330 340 350
IIQENLWLKL SEMPYRAAAL SATAAGRYIY ISGGTTEQIS GLKTAWRYDM
360 370 380 390 400
DDNSWTKLPD LPIGLVFHTM VTCGGTVYSV GGSIAPRRYV SNIYRYDERK
410 420 430 440 450
EAWCLAGKMS IPMDGTAVIT KGDRNLYIVT GRCLVKGYIS RVGVVDCFDT
460 470 480 490 500
CTGEVVQCIT FPIEFNHRPL LSFHQDNILR VHSHRQSVEI NLQKIKANKS
510 520 530 540 550
TTSVPLLPNS CPLDVSHAIC SIGDSKVFVC GGVTTASDVQ TKDYTINPNA
560 570 580
YLLDQKIGEW QTLACPPEAL DCPACCLAKL PCKILQRI
Length:588
Mass (Da):66,750
Last modified:March 1, 2003 - v1
Checksum:i088F8F663B8A2E0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK030197 mRNA Translation: BAC26835.1
AL732563 Genomic DNA No translation available.
CCDSiCCDS18118.1
RefSeqiNP_001002787.1, NM_001002787.2
UniGeneiMm.348215

Genome annotation databases

EnsembliENSMUST00000095107; ENSMUSP00000092725; ENSMUSG00000070999
GeneIDi442829
KEGGimmu:442829
UCSCiuc008srg.1 mouse

Similar proteinsi

Entry informationi

Entry nameiCALI_MOUSE
AccessioniPrimary (citable) accession number: Q8CDE2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health