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Protein
Submitted name:

Eph receptor A7, isoform CRA_a

Gene

Epha7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Eph receptor A7, isoform CRA_aImported
Gene namesi
Name:Epha7Imported
ORF Names:mCG_14600Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95276 Epha7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei555 – 578HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501410733928 – 610Sequence analysisAdd BLAST583

Proteomic databases

MaxQBiQ8CC52

Expressioni

Gene expression databases

BgeeiENSMUSG00000028289

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ8CC52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 210Eph LBDInterPro annotationAdd BLAST179
Domaini331 – 441Fibronectin type-IIIInterPro annotationAdd BLAST111
Domaini442 – 537Fibronectin type-IIIInterPro annotationAdd BLAST96

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0196 Eukaryota
COG0515 LUCA
HOVERGENiHBG062180
KOiK05108

Family and domain databases

CDDicd10485 EphR_LBD_A7, 1 hit
cd00063 FN3, 2 hits
Gene3Di2.60.120.2601 hit
2.60.40.102 hits
InterProiView protein in InterPro
IPR034283 EphA7_rcpt_lig-bd
IPR001090 Ephrin_rcpt_lig-bd_dom
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR008979 Galactose-bd-like_sf
IPR009030 Growth_fac_rcpt_cys_sf
IPR013783 Ig-like_fold
IPR011641 Tyr-kin_ephrin_A/B_rcpt-like
IPR001426 Tyr_kinase_rcpt_V_CS
PfamiView protein in Pfam
PF01404 Ephrin_lbd, 1 hit
PF00041 fn3, 2 hits
SMARTiView protein in SMART
SM00615 EPH_lbd, 1 hit
SM01411 Ephrin_rec_like, 1 hit
SM00060 FN3, 2 hits
SUPFAMiSSF49265 SSF49265, 1 hit
SSF49785 SSF49785, 1 hit
SSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS51550 EPH_LBD, 1 hit
PS50853 FN3, 2 hits
PS00790 RECEPTOR_TYR_KIN_V_1, 1 hit
PS00791 RECEPTOR_TYR_KIN_V_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CC52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVQTRFPSW IILCYIWLLG FAHTGEAQAA KEVLLLDSKA QQTELEWISS
60 70 80 90 100
PPSGWEEISG LDENYTPIRT YQVCQVMEPN QNNWLRTNWI SKGNAQRIFV
110 120 130 140 150
ELKFTLRDCN SLPGVLGTCK ETFNLYYYET DYDTGRNIRE NLYVKIDTIA
160 170 180 190 200
ADESFTQGDL GERKMKLNTE VREIGPLSKK GFYLAFQDVG ACIALVSVKV
210 220 230 240 250
YYKKCWSIVE NLAVFPDTVT GSEFSSLVEV RGTCVSSAEE EAENSPRMHC
260 270 280 290 300
SAEGEWLVPI GKCICKAGYQ QKGDTCEPCG RRFYKSSSQD LQCSRCPTHS
310 320 330 340 350
FSDREGSSRC ECEDGYYRAP SDPPYVACTR PPSAPQNLIF NINQTTVSLE
360 370 380 390 400
WSPPADNGGR NDVTYRILCK RCSWEQGECV PCGSNIGYMP QQTGLEDNYV
410 420 430 440 450
TVMDLLAHAN YTFEVEAVNG VSDLSRSQRL FAAVSITTGQ AAPSQVSGVM
460 470 480 490 500
KERVLQRSVQ LSWQEPEHPN GVITEYEIKY YEKDQRERTY STLKTKSTSA
510 520 530 540 550
SINNLKPGTV YVFQIRAVTA AGYGNYSPRL DVATLEEASG KMFEATAVSS
560 570 580 590 600
EQNPVIIIAV VAVAGTIILV FMVFGFIIGR RHCGYSKADQ EGDEELYFHS
610
LVTNEHLSVL
Length:610
Mass (Da):68,286
Last modified:March 1, 2003 - v1
Checksum:iE61310A72FE1E739
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033903 mRNA Translation: BAC28509.1
CH466538 Genomic DNA Translation: EDL05515.1
RefSeqiNP_001116361.1, NM_001122889.1
NP_001277363.1, NM_001290434.1
NP_034271.3, NM_010141.4
UniGeneiMm.257266

Genome annotation databases

GeneIDi13841
KEGGimmu:13841
UCSCiuc008sem.3 mouse

Similar proteinsi

Entry informationi

Entry nameiQ8CC52_MOUSE
AccessioniPrimary (citable) accession number: Q8CC52
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)