Putative uncharacterized protein - Mus musculus (Mouse)

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Unreviewed, UniProtKB/TrEMBL Q8CBT3 (Q8CBT3_MOUSE)

Last modified February 9, 2010. Version 62. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAC29034.1

Gene names

Name:

Chuk MGI 99484

Organism

Mus musculus (Mouse) EMBL BAC29034.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	745 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily.

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304V2 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305V3 Transferase
Gene Ontology (GO)
Biological process	I-kappaB phosphorylation Traceable author statement. Source: MGI lactation Inferred from genetic interaction. Source: MGI mammary gland alveolus development Inferred from genetic interaction. Source: MGI mammary gland epithelial cell proliferation Inferred from genetic interaction. Source: MGI morphogenesis of an epithelial sheet Inferred from mutant phenotype. Source: MGI odontogenesis of dentine-containing tooth Inferred from mutant phenotype. Source: MGI osteoclast differentiation Inferred from genetic interaction. Source: MGI positive regulation of I-kappaB kinase/NF-kappaB cascade Inferred from genetic interaction. Source: MGI
Cellular component	cytoplasm Traceable author statement. Source: MGI
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW identical protein binding Inferred from electronic annotation. Source: Compara receptor signaling protein serine/threonine kinase activity Traceable author statement. Source: MGI
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q8CBT3-1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 48C9E01C17A61184
Show »

745

84,771

        10         20         30         40         50         60 
MERPPGLRPG AGGPWEMRER LGTGGFGNVS LYQHRELDLK IAIKSCRLEL SSKNRERWCH 

        70         80         90        100        110        120 
EIQIMKKLDH ANVVKACDVP EELNFLINDV PLLAMEYCSG GDLRKLLNKP ENCCGLKESQ 

       130        140        150        160        170        180 
ILSLLSDIGS GIRYLHENKI IHRDLKPENI VLQDVGGKTI HKIIDLGYAK DVDQGSLCTS 

       190        200        210        220        230        240 
FVGTLQYLAP ELFENKPYTA TVDYWSFGTM VFECIAGYRP FLHHLQPFTW HEKIKKKDPK 

       250        260        270        280        290        300 
CIFACEEMTG EVRFSSHLPQ PNSLCSLIVE PMESWLQLML NWDPQQRGGP IDLTLKQPRC 

       310        320        330        340        350        360 
IALMDHILNL KIVHILNMTS AKIISFLLPC DESLHSLQSR IERETGINTG SQELLSETGI 

       370        380        390        400        410        420 
SLDPRKPASQ CVLDGVRGCD SYMVYLFDKS KTVYEGPFAS RSLSDCVNYI VQDSKIQLPI 

       430        440        450        460        470        480 
IQLRKVWAEA VHYVSGLKED YSRLFQGQRA AMLSLLRYNA NLTKMKNTLI SASQQLKAKL 

       490        500        510        520        530        540 
EFFRKSIQLD LERYSEQMTY GISSEKMLKA WKEMEEKAIH YSEVGVIGYL EDQIMSLHTE 

       550        560        570        580        590        600 
IMELQKSPYG RRQGDLMESL EQRAIDLYKQ LKHRPPDHLY SDSTEMVKII VHTVQSQDRV 

       610        620        630        640        650        660 
LKELFGHLSK LLGCKQKIID LLPKVEVALS NIKEADNTVM FMQGKRQKEI WHLLKIACTQ 

       670        680        690        700        710        720 
SSARSLVGYS LEGTVTPPVS AWLPPTLADR EHPLTCVVTP QDGETLAQMI EENLNCLGHL 

       730        740 
STIIREANED QSSSLMSLDW SWLAE

References

[1]

"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.

expand/collapse author list

Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J EMBL BAC29034.1.
Tissue: Urinary bladder EMBL BAC29034.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK035326 mRNA. Translation: BAC29034.1.
IPI	IPI00119213.
RefSeq	NP_001155882.1. NP_031726.2.
UniGene	Mm.3996
3D structure databases
SMR	Q8CBT3. Positions 19-330.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8CBT3.
Genome annotation databases
Ensembl	ENSMUST00000026217; ENSMUSP00000026217; ENSMUSG00000025199; Mus musculus. [Genome view]
GeneID	12675.
KEGG	mmu:12675.
Organism-specific databases
MGI	MGI:99484. Chuk.
Phylogenomic databases
HOVERGEN	Q8CBT3.
InParanoid	Q8CBT3.
Gene expression databases
ArrayExpress	Q8CBT3.
Bgee	Q8CBT3.
Genevestigator	Q8CBT3.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q8CBT3_MOUSE

Accession

Primary (citable) accession number: Q8CBT3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	February 9, 2010
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information