Atf2

Functionⁱ

GO - Molecular functionⁱ

nucleic acid binding Source: InterPro
transcription factor activity, sequence-specific DNA binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

regulation of transcription from RNA polymerase II promoter Source: InterPro

Complete GO annotation...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Putative uncharacterized proteinImported
Gene namesⁱ	Name:Atf2Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:109349. Atf2.

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	385 – 410	HelicalSequence analysisAdd BLAST		26

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
nucleus Source: InterPro

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q8CBR9.

PaxDbⁱ

Q8CBR9.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000027104.

Bgeeⁱ

ENSMUSG00000027104.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8CBR9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	7 – 31	C2H2-typeInterPro annotationAdd BLAST		25
Domainⁱ	334 – 377	BZIP (basic-leucine zipper)InterPro annotationAdd BLAST		44

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1414. Eukaryota. ENOG4111CH5. LUCA.
HOVERGENⁱ	HBG004300.

Family and domain databases

InterProⁱ	View protein in InterPro IPR029836. ATF-2. IPR004827. bZIP. IPR016378. TF_CRE-BP1-typ. IPR013087. Znf_C2H2_type.
PANTHERⁱ	PTHR19304:SF33. PTHR19304:SF33. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00170. bZIP_1. 1 hit.
PIRSFⁱ	PIRSF003153. ATF2_CRE-BP1. 1 hit.
SMARTⁱ	View protein in SMART SM00338. BRLZ. 1 hit.
SUPFAMⁱ	SSF57667. SSF57667. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 1 hit. PS50157. ZINC_FINGER_C2H2_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q8CBR9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSDDKPFLCT APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RNDSVIVADQ 
        60         70         80         90        100
TPTPTRFLKN CEEVGLFNEL ASPFENEFKK ASEDDIKKMP LDLSPLATPI 
       110        120        130        140        150
IRSKIEEPSV VETTHQDSPL PHPESTTSDE KEVPLAQTAQ PTSAIVRPAS 
       160        170        180        190        200
LQVPNVLLTS SDSSVIIQQA VPSPTSSTVI TQAPSSNRPI VPVPGPFPLL 
       210        220        230        240        250
LHLPNGQTMP VAIPASITSS NVHVPAAVPL VRPVTMVPSV PGIPGPSSPQ 
       260        270        280        290        300
PVQSEAKMRL KAALTQQHPP VTNGDTVKGH GSGLVRTQSE ESRPQSLQQP 
       310        320        330        340        350
ATSTTETPAS PAHTTPQTQN TSGRRRRAAN EDPDEKRRKF LERNRAAASR 
       360        370        380        390        400
CRQKRKVWVQ SLEKKAEDLS SLNGQLQVWA QAVCFYLLVS NIGVAWFVGL 
       410        420
VWFGLVWFFV CSFARQGFSV

Length:420

Mass (Da):45,728

Last modified:March 1, 2003 - v1

Checksum:ⁱD15134149A971ACA

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK035438 mRNA. Translation: BAC29065.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001271298.1. NM_001284369.1. NP_001271299.1. NM_001284370.1. NP_001271300.1. NM_001284371.1.
UniGeneⁱ	Mm.209903.

Genome annotation databases

GeneIDⁱ	11909.
UCSC genome browser More...UCSCⁱ	uc008kdj.2. mouse.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK035438 mRNA. Translation: BAC29065.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001271298.1. NM_001284369.1. NP_001271299.1. NM_001284370.1. NP_001271300.1. NM_001284371.1.
UniGeneⁱ	Mm.209903.

3D structure databases

ProteinModelPortalⁱ	Q8CBR9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	Q8CBR9.

PaxDbⁱ

Q8CBR9.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	11909.
UCSC genome browser More...UCSCⁱ	uc008kdj.2. mouse.

Organism-specific databases

CTDⁱ	1386.
MGIⁱ	MGI:109349. Atf2.

Phylogenomic databases

eggNOGⁱ	KOG1414. Eukaryota. ENOG4111CH5. LUCA.
HOVERGENⁱ	HBG004300.

Miscellaneous databases

ChiTaRSⁱ	Atf2. mouse.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000027104.

Bgeeⁱ

ENSMUSG00000027104.

Family and domain databases

InterProⁱ	View protein in InterPro IPR029836. ATF-2. IPR004827. bZIP. IPR016378. TF_CRE-BP1-typ. IPR013087. Znf_C2H2_type.
PANTHERⁱ	PTHR19304:SF33. PTHR19304:SF33. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00170. bZIP_1. 1 hit.
PIRSFⁱ	PIRSF003153. ATF2_CRE-BP1. 1 hit.
SMARTⁱ	View protein in SMART SM00338. BRLZ. 1 hit.
SUPFAMⁱ	SSF57667. SSF57667. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 1 hit. PS50157. ZINC_FINGER_C2H2_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q8CBR9_MOUSE
Accessionⁱ	Q8CBR9Primary (citable) accession number: Q8CBR9
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 1, 2003
	Last sequence update:	March 1, 2003
	Last modified:	July 5, 2017
	This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

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Supporting data

UniProtKB - Q8CBR9 (Q8CBR9_MOUSE)

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Putative uncharacterized protein

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ