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Protein
Submitted name:

Aspartyl/asparaginyl beta-hydroxylase

Gene

Asph

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Aspartyl/asparaginyl beta-hydroxylaseImported
Gene namesi
Name:AsphImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1914186. Asph.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 658636Sequence analysisPRO_5007712891Add
BLAST

Proteomic databases

PeptideAtlasiQ8CBM2.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000077273.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini241 – 421181TPR_REGIONInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili281 – 30828Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3696. Eukaryota.
COG3555. LUCA.
GeneTreeiENSGT00530000063281.
HOGENOMiHOG000231625.
HOVERGENiHBG004290.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
2.60.120.330. 1 hit.
InterProiIPR007943. Asp-B-hydro/Triadin_dom.
IPR007803. Asp/Arg/Pro-Hydrxlase.
IPR027443. IPNS-like.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF05279. Asp-B-Hydro_N. 1 hit.
PF05118. Asp_Arg_Hydrox. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00028. TPR. 2 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CBM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVIALLGVWT SVAVVWFDLV DYEEVLGKLG VYDADGDGDF DVDDAKVLLG
60 70 80 90 100
LKERSPSERT FPPEEEAETH AELEEQAPEG ADIQNVEDEV KEQIQSLLQE
110 120 130 140 150
SVHTDHDLEA DGLAGEPQPE VEDFLTVTDS DDRFEDLEPG TVHEEIEDTY
160 170 180 190 200
HVEDTASQNH PNDMEEMTNE QENSEEVRHQ DYDEPVYEPS EHEGVAISDN
210 220 230 240 250
TIDDSSIISE EINVASVEEQ QDTPPVKKKK PKLLNKFDKT IKAELDAAEK
260 270 280 290 300
LRKRGKIEEA VNAFEELVRK YPQSPRARYG KAQCEDDLAE KQRSNEVLRR
310 320 330 340 350
AIETYQEAAD LPDAPTDLVK LSLKRRSERQ QFLGHMRGSL LTLQRLVQLF
360 370 380 390 400
PSDTTLKNDL GVGYLLLGDN DSAKKVYEEV LNVTPNDGFA KVHYGFILKA
410 420 430 440 450
QNKISESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN KEAYKWYELG
460 470 480 490 500
HKRGHFASVW QRSLYNVNGL KAQPWWTPRE TGYTELVKSL ERNWKLIRDE
510 520 530 540 550
GLMVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRKNENA CKGAPKTCAL
560 570 580 590 600
LEKFSETTGC RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC
610 620 630 640 650
KIRCANETRT WEEGKVLIFD DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ

QRRSLPAI
Length:658
Mass (Da):75,128
Last modified:March 1, 2003 - v1
Checksum:i2BA0A5C8E06801C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671970 Genomic DNA. No translation available.
AL732508 Genomic DNA. No translation available.
AL773548 Genomic DNA. No translation available.
AK035735 mRNA. Translation: BAC29171.1.
RefSeqiNP_001171320.1. NM_001177849.1.
NP_001277296.1. NM_001290367.1.
UniGeneiMm.222206.
Mm.412008.

Genome annotation databases

EnsembliENSMUST00000108339; ENSMUSP00000103976; ENSMUSG00000028207.
GeneIDi65973.
UCSCiuc008ryh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671970 Genomic DNA. No translation available.
AL732508 Genomic DNA. No translation available.
AL773548 Genomic DNA. No translation available.
AK035735 mRNA. Translation: BAC29171.1.
RefSeqiNP_001171320.1. NM_001177849.1.
NP_001277296.1. NM_001290367.1.
UniGeneiMm.222206.
Mm.412008.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000077273.

Proteomic databases

PeptideAtlasiQ8CBM2.

Protocols and materials databases

DNASUi65973.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000108339; ENSMUSP00000103976; ENSMUSG00000028207.
GeneIDi65973.
UCSCiuc008ryh.1. mouse.

Organism-specific databases

CTDi444.
MGIiMGI:1914186. Asph.

Phylogenomic databases

eggNOGiKOG3696. Eukaryota.
COG3555. LUCA.
GeneTreeiENSGT00530000063281.
HOGENOMiHOG000231625.
HOVERGENiHBG004290.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
2.60.120.330. 1 hit.
InterProiIPR007943. Asp-B-hydro/Triadin_dom.
IPR007803. Asp/Arg/Pro-Hydrxlase.
IPR027443. IPNS-like.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF05279. Asp-B-Hydro_N. 1 hit.
PF05118. Asp_Arg_Hydrox. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00028. TPR. 2 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Urinary bladderImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8CBM2_MOUSE
AccessioniPrimary (citable) accession number: Q8CBM2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.