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Q8CBE3 (WDR37_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
WD repeat-containing protein 37
Gene names
Name:Wdr37
Synonyms:Kiaa0982
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length496 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 7 WD repeats.

Sequence caution

The sequence BAC98064.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   DomainRepeat
WD repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 496496WD repeat-containing protein 37
PRO_0000051388

Regions

Repeat154 – 19441WD 1
Repeat197 – 23640WD 2
Repeat281 – 32040WD 3
Repeat323 – 36240WD 4
Repeat367 – 40539WD 5
Repeat408 – 44740WD 6
Repeat454 – 49542WD 7

Experimental info

Sequence conflict691F → L in BAC27934. Ref.2
Sequence conflict1391T → I in AAH46236. Ref.3
Sequence conflict2241H → N in BAC27934. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q8CBE3 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: D647D239E5F6EA08

FASTA49655,046
        10         20         30         40         50         60 
MPTESGSCST ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRSTLLE 

        70         80         90        100        110        120 
LFGQIEREFE NLYIENLELR REIDTLNERL AGEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 

       130        140        150        160        170        180 
KLKTTYKAST SKIVSSFKTT TSRAICQLVK EYIGHRDGIW DVSVTRTQPI VLGTASADHT 

       190        200        210        220        230        240 
ALLWSIETGK CLVKYAGHVG SVNSIKFHPS EQLALTASGD QTAHIWRYVV QLPTPQPVAD 

       250        260        270        280        290        300 
TSQQISGEDE IECSDKDEPD IDGDVSSDCP TVRVPLTSLK SHQGVVIAAD WLVGGKQVVT 

       310        320        330        340        350        360 
ASWDRTANLY DVETSELVHS LTGHDQELTH CCTHPTQRLV VTSSRDTTFR LWDFRDPSIH 

       370        380        390        400        410        420 
SVNVFQGHTD TVTSAVFTVG DNVVSGSDDR TVKVWDLKNM RSPIATIRTD SAINRINVCV 

       430        440        450        460        470        480 
GQKIIALPHD NRQVRLFDMS GVRLARLPRS SRQGHRRMVC CSAWSEDHPI CNLFTCGFDR 

       490 
QAIGWNINIP ALLQEK 

« Hide

References

[1]"Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryonic tail.
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Cerebellum and Olfactory bulb.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK129254 mRNA. Translation: BAC98064.1. Different initiation.
AK032582 mRNA. Translation: BAC27934.1.
AK036203 mRNA. Translation: BAC29346.1.
BC046236 mRNA. Translation: AAH46236.1.
CCDSCCDS26232.1.
RefSeqNP_001034477.1. NM_001039388.2.
NP_766033.1. NM_172445.3.
XP_006516532.1. XM_006516469.1.
XP_006516533.1. XM_006516470.1.
UniGeneMm.284654.

3D structure databases

ProteinModelPortalQ8CBE3.
SMRQ8CBE3. Positions 98-488.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid228908. 3 interactions.
IntActQ8CBE3. 2 interactions.
MINTMINT-4140335.

PTM databases

PhosphoSiteQ8CBE3.

Proteomic databases

MaxQBQ8CBE3.
PaxDbQ8CBE3.
PRIDEQ8CBE3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000021572; ENSMUSP00000021572; ENSMUSG00000021147.
ENSMUST00000054251; ENSMUSP00000062174; ENSMUSG00000021147.
GeneID207615.
KEGGmmu:207615.
UCSCuc007pki.1. mouse.

Organism-specific databases

CTD22884.
MGIMGI:1920393. Wdr37.
RougeSearch...

Phylogenomic databases

eggNOGCOG2319.
GeneTreeENSGT00640000091456.
HOGENOMHOG000013185.
HOVERGENHBG057072.
InParanoidQ8CBE3.
OMATGLPRDM.
OrthoDBEOG77DJ5K.
PhylomeDBQ8CBE3.
TreeFamTF105876.

Gene expression databases

ArrayExpressQ8CBE3.
BgeeQ8CBE3.
CleanExMM_WDR37.
GenevestigatorQ8CBE3.

Family and domain databases

Gene3D2.130.10.10. 2 hits.
InterProIPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF00400. WD40. 5 hits.
[Graphical view]
PRINTSPR00320. GPROTEINBRPT.
SMARTSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMSSF50978. SSF50978. 2 hits.
PROSITEPS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio371979.
PROQ8CBE3.
SOURCESearch...

Entry information

Entry nameWDR37_MOUSE
AccessionPrimary (citable) accession number: Q8CBE3
Secondary accession number(s): Q80Y96, Q8CCL2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot