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Q8CBE3

- WDR37_MOUSE

UniProt

Q8CBE3 - WDR37_MOUSE

Protein

WD repeat-containing protein 37

Gene

Wdr37

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    WD repeat-containing protein 37
    Gene namesi
    Name:Wdr37
    Synonyms:Kiaa0982
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:1920393. Wdr37.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 496496WD repeat-containing protein 37PRO_0000051388Add
    BLAST

    Proteomic databases

    MaxQBiQ8CBE3.
    PaxDbiQ8CBE3.
    PRIDEiQ8CBE3.

    PTM databases

    PhosphoSiteiQ8CBE3.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8CBE3.
    BgeeiQ8CBE3.
    CleanExiMM_WDR37.
    GenevestigatoriQ8CBE3.

    Interactioni

    Protein-protein interaction databases

    BioGridi228908. 3 interactions.
    IntActiQ8CBE3. 2 interactions.
    MINTiMINT-4140335.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CBE3.
    SMRiQ8CBE3. Positions 98-488.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati154 – 19441WD 1Add
    BLAST
    Repeati197 – 23640WD 2Add
    BLAST
    Repeati281 – 32040WD 3Add
    BLAST
    Repeati323 – 36240WD 4Add
    BLAST
    Repeati367 – 40539WD 5Add
    BLAST
    Repeati408 – 44740WD 6Add
    BLAST
    Repeati454 – 49542WD 7Add
    BLAST

    Sequence similaritiesi

    Contains 7 WD repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, WD repeat

    Phylogenomic databases

    eggNOGiCOG2319.
    GeneTreeiENSGT00640000091456.
    HOGENOMiHOG000013185.
    HOVERGENiHBG057072.
    InParanoidiQ8CBE3.
    OMAiTGLPRDM.
    OrthoDBiEOG77DJ5K.
    PhylomeDBiQ8CBE3.
    TreeFamiTF105876.

    Family and domain databases

    Gene3Di2.130.10.10. 2 hits.
    InterProiIPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF00400. WD40. 5 hits.
    [Graphical view]
    PRINTSiPR00320. GPROTEINBRPT.
    SMARTiSM00320. WD40. 6 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 2 hits.
    PROSITEiPS00678. WD_REPEATS_1. 2 hits.
    PS50082. WD_REPEATS_2. 5 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8CBE3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPTESGSCST ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL    50
    PSSVRSTLLE LFGQIEREFE NLYIENLELR REIDTLNERL AGEGQAIDGA 100
    ELSKGQLKTK ASHSTSQLSQ KLKTTYKAST SKIVSSFKTT TSRAICQLVK 150
    EYIGHRDGIW DVSVTRTQPI VLGTASADHT ALLWSIETGK CLVKYAGHVG 200
    SVNSIKFHPS EQLALTASGD QTAHIWRYVV QLPTPQPVAD TSQQISGEDE 250
    IECSDKDEPD IDGDVSSDCP TVRVPLTSLK SHQGVVIAAD WLVGGKQVVT 300
    ASWDRTANLY DVETSELVHS LTGHDQELTH CCTHPTQRLV VTSSRDTTFR 350
    LWDFRDPSIH SVNVFQGHTD TVTSAVFTVG DNVVSGSDDR TVKVWDLKNM 400
    RSPIATIRTD SAINRINVCV GQKIIALPHD NRQVRLFDMS GVRLARLPRS 450
    SRQGHRRMVC CSAWSEDHPI CNLFTCGFDR QAIGWNINIP ALLQEK 496
    Length:496
    Mass (Da):55,046
    Last modified:March 1, 2003 - v1
    Checksum:iD647D239E5F6EA08
    GO

    Sequence cautioni

    The sequence BAC98064.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti69 – 691F → L in BAC27934. (PubMed:16141072)Curated
    Sequence conflicti139 – 1391T → I in AAH46236. (PubMed:15489334)Curated
    Sequence conflicti224 – 2241H → N in BAC27934. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK129254 mRNA. Translation: BAC98064.1. Different initiation.
    AK032582 mRNA. Translation: BAC27934.1.
    AK036203 mRNA. Translation: BAC29346.1.
    BC046236 mRNA. Translation: AAH46236.1.
    CCDSiCCDS26232.1.
    RefSeqiNP_001034477.1. NM_001039388.2.
    NP_766033.1. NM_172445.3.
    XP_006516532.1. XM_006516469.1.
    XP_006516533.1. XM_006516470.1.
    UniGeneiMm.284654.

    Genome annotation databases

    EnsembliENSMUST00000021572; ENSMUSP00000021572; ENSMUSG00000021147.
    ENSMUST00000054251; ENSMUSP00000062174; ENSMUSG00000021147.
    GeneIDi207615.
    KEGGimmu:207615.
    UCSCiuc007pki.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK129254 mRNA. Translation: BAC98064.1 . Different initiation.
    AK032582 mRNA. Translation: BAC27934.1 .
    AK036203 mRNA. Translation: BAC29346.1 .
    BC046236 mRNA. Translation: AAH46236.1 .
    CCDSi CCDS26232.1.
    RefSeqi NP_001034477.1. NM_001039388.2.
    NP_766033.1. NM_172445.3.
    XP_006516532.1. XM_006516469.1.
    XP_006516533.1. XM_006516470.1.
    UniGenei Mm.284654.

    3D structure databases

    ProteinModelPortali Q8CBE3.
    SMRi Q8CBE3. Positions 98-488.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 228908. 3 interactions.
    IntActi Q8CBE3. 2 interactions.
    MINTi MINT-4140335.

    PTM databases

    PhosphoSitei Q8CBE3.

    Proteomic databases

    MaxQBi Q8CBE3.
    PaxDbi Q8CBE3.
    PRIDEi Q8CBE3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000021572 ; ENSMUSP00000021572 ; ENSMUSG00000021147 .
    ENSMUST00000054251 ; ENSMUSP00000062174 ; ENSMUSG00000021147 .
    GeneIDi 207615.
    KEGGi mmu:207615.
    UCSCi uc007pki.1. mouse.

    Organism-specific databases

    CTDi 22884.
    MGIi MGI:1920393. Wdr37.
    Rougei Search...

    Phylogenomic databases

    eggNOGi COG2319.
    GeneTreei ENSGT00640000091456.
    HOGENOMi HOG000013185.
    HOVERGENi HBG057072.
    InParanoidi Q8CBE3.
    OMAi TGLPRDM.
    OrthoDBi EOG77DJ5K.
    PhylomeDBi Q8CBE3.
    TreeFami TF105876.

    Miscellaneous databases

    NextBioi 371979.
    PROi Q8CBE3.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8CBE3.
    Bgeei Q8CBE3.
    CleanExi MM_WDR37.
    Genevestigatori Q8CBE3.

    Family and domain databases

    Gene3Di 2.130.10.10. 2 hits.
    InterProi IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF00400. WD40. 5 hits.
    [Graphical view ]
    PRINTSi PR00320. GPROTEINBRPT.
    SMARTi SM00320. WD40. 6 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 2 hits.
    PROSITEi PS00678. WD_REPEATS_1. 2 hits.
    PS50082. WD_REPEATS_2. 5 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
      DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryonic tail.
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Cerebellum and Olfactory bulb.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Brain.

    Entry informationi

    Entry nameiWDR37_MOUSE
    AccessioniPrimary (citable) accession number: Q8CBE3
    Secondary accession number(s): Q80Y96, Q8CCL2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2004
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3