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Q8CAF8

- Q8CAF8_MOUSE

UniProt

Q8CAF8 - Q8CAF8_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Gabbr1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled GABA receptor activity Source: Ensembl

GO - Biological processi

  1. adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Source: Ensembl
  2. gamma-aminobutyric acid signaling pathway Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Gabbr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1860139. Gabbr1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. G-protein coupled receptor dimeric complex Source: MGI
  3. G-protein coupled receptor heterodimeric complex Source: Ensembl
  4. integral component of plasma membrane Source: Ensembl
  5. membrane Source: MGI
  6. postsynaptic membrane Source: MGI
  7. presynaptic membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ8CAF8.
ExpressionAtlasiQ8CAF8. baseline and differential.
GenevestigatoriQ8CAF8.

Structurei

3D structure databases

ProteinModelPortaliQ8CAF8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG051688.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR002455. GPCR3_GABA-B.
IPR000337. GPCR_3.
IPR017978. GPCR_3_C.
IPR002456. GPCR_3_GABA_rcpt_B1.
IPR028082. Peripla_BP_I.
[Graphical view]
PANTHERiPTHR10519. PTHR10519. 1 hit.
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
[Graphical view]
PRINTSiPR01177. GABAB1RECPTR.
PR00248. GPCRMGR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8CAF8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
IHHDSKCDPG QATKYLYELL YNDPIKIILM PGCSSVSTLV AEAARMWNLI
60 70 80 90 100
VLSYGSSSPA LSNRQRFPTF FRTHPSATLH NPTRVKLFEK WGWKKIATIQ
110 120 130 140 150
QTTEVFTSTL DDLEERVKEA GIEITFRQSF FSDPAVPVKN LKRQDARIIV
160 170 180 190 200
GLFYETEARK VFCEVYKERL FGKKYVWFLI GWYADNWFKT YDPSINCTVE
210 220 230 240 250
EMTEAVEGHI TTEIVMLNPA NTRSISNMTS QEFVEKLTKR LKRHPEETGG
260 270 280 290 300
FQEAPLAYDA IWALALALNK TSGGGGRSGV RLEDFNYNNQ TITDQIYRAM
310 320 330 340 350
NSSSFEGVSG HVVFDASGSR MAWTLIEQLQ GGSYKKIGYY DSTKDDLSWS
360 370 380 390 400
KTDKWIGGSP PADQTLVIKT FRFLSQKLFI SVSVLSSLGI VLAVVCLSFN
410 420 430 440 450
IYNSHVRYIQ NSQPNLNNLT AVGCSLALAA VFPLGLDGYH IGRSQFPFVC
460 470 480 490 500
QARLWLLGLG FSLGYGSMFT KIWWVHTVFT KKEEKKEWRK TLEPWKLYAT
510 520 530 540 550
VGLLVGMDIL TLAIWQIVDP LHRTIETFAK EEPKEDIDVS ILPQLEHCSS
560 570 580 590 600
KKMNTWLGIF YGYKGLLLLL GIFLAYETKS VSTEKINDHR AVGMAIYNVA
610 620 630 640 650
VLCLITAPVT MILSSQQDAA FAFASLAIVF SSYITLVVLF VPKMRRLITR
660 670 680 690 700
GEWQSEAQDT MKTGSSTNNN EEEKSRLLEK ENRELEKIIA EKEERVSELR
710 720 730 740
HQLQSRQQIR SRRHPPTPPD PSGGLPRGPS EPPDRLSCDG SRVHLLYK
Length:748
Mass (Da):84,777
Last modified:March 1, 2003 - v1
Checksum:i991B3DB1749A8614
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK038844 mRNA. Translation: BAC30149.1.
UniGeneiMm.32191.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK038844 mRNA. Translation: BAC30149.1 .
UniGenei Mm.32191.

3D structure databases

ProteinModelPortali Q8CAF8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1860139. Gabbr1.

Phylogenomic databases

HOVERGENi HBG051688.

Miscellaneous databases

ChiTaRSi GABBR1. mouse.
SOURCEi Search...

Gene expression databases

Bgeei Q8CAF8.
ExpressionAtlasi Q8CAF8. baseline and differential.
Genevestigatori Q8CAF8.

Family and domain databases

InterProi IPR001828. ANF_lig-bd_rcpt.
IPR002455. GPCR3_GABA-B.
IPR000337. GPCR_3.
IPR017978. GPCR_3_C.
IPR002456. GPCR_3_GABA_rcpt_B1.
IPR028082. Peripla_BP_I.
[Graphical view ]
PANTHERi PTHR10519. PTHR10519. 1 hit.
Pfami PF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
[Graphical view ]
PRINTSi PR01177. GABAB1RECPTR.
PR00248. GPCRMGR.
SUPFAMi SSF53822. SSF53822. 1 hit.
PROSITEi PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.

Entry informationi

Entry nameiQ8CAF8_MOUSE
AccessioniPrimary (citable) accession number: Q8CAF8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)