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Protein
Submitted name:

Putative uncharacterized protein

Gene

Gabbr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Gabbr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1860139. Gabbr1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei378 – 40326HelicalSequence analysisAdd
BLAST
Transmembranei415 – 43420HelicalSequence analysisAdd
BLAST
Transmembranei454 – 47421HelicalSequence analysisAdd
BLAST
Transmembranei495 – 51824HelicalSequence analysisAdd
BLAST
Transmembranei555 – 57521HelicalSequence analysisAdd
BLAST
Transmembranei595 – 61319HelicalSequence analysisAdd
BLAST
Transmembranei619 – 64123HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8CAF8.
PeptideAtlasiQ8CAF8.

Expressioni

Gene expression databases

BgeeiQ8CAF8.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025338.

Structurei

3D structure databases

ProteinModelPortaliQ8CAF8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini385 – 663279G_PROTEIN_RECEP_F3_4InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili668 – 70942Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 3 family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1055. Eukaryota.
ENOG410XNN1. LUCA.
HOVERGENiHBG051688.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR002455. GPCR3_GABA-B.
IPR000337. GPCR_3.
IPR017978. GPCR_3_C.
IPR002456. GPCR_3_GABA_rcpt_B1.
IPR028082. Peripla_BP_I.
[Graphical view]
PANTHERiPTHR10519. PTHR10519. 1 hit.
PTHR10519:SF42. PTHR10519:SF42. 1 hit.
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
[Graphical view]
PRINTSiPR01177. GABAB1RECPTR.
PR00248. GPCRMGR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8CAF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IHHDSKCDPG QATKYLYELL YNDPIKIILM PGCSSVSTLV AEAARMWNLI
60 70 80 90 100
VLSYGSSSPA LSNRQRFPTF FRTHPSATLH NPTRVKLFEK WGWKKIATIQ
110 120 130 140 150
QTTEVFTSTL DDLEERVKEA GIEITFRQSF FSDPAVPVKN LKRQDARIIV
160 170 180 190 200
GLFYETEARK VFCEVYKERL FGKKYVWFLI GWYADNWFKT YDPSINCTVE
210 220 230 240 250
EMTEAVEGHI TTEIVMLNPA NTRSISNMTS QEFVEKLTKR LKRHPEETGG
260 270 280 290 300
FQEAPLAYDA IWALALALNK TSGGGGRSGV RLEDFNYNNQ TITDQIYRAM
310 320 330 340 350
NSSSFEGVSG HVVFDASGSR MAWTLIEQLQ GGSYKKIGYY DSTKDDLSWS
360 370 380 390 400
KTDKWIGGSP PADQTLVIKT FRFLSQKLFI SVSVLSSLGI VLAVVCLSFN
410 420 430 440 450
IYNSHVRYIQ NSQPNLNNLT AVGCSLALAA VFPLGLDGYH IGRSQFPFVC
460 470 480 490 500
QARLWLLGLG FSLGYGSMFT KIWWVHTVFT KKEEKKEWRK TLEPWKLYAT
510 520 530 540 550
VGLLVGMDIL TLAIWQIVDP LHRTIETFAK EEPKEDIDVS ILPQLEHCSS
560 570 580 590 600
KKMNTWLGIF YGYKGLLLLL GIFLAYETKS VSTEKINDHR AVGMAIYNVA
610 620 630 640 650
VLCLITAPVT MILSSQQDAA FAFASLAIVF SSYITLVVLF VPKMRRLITR
660 670 680 690 700
GEWQSEAQDT MKTGSSTNNN EEEKSRLLEK ENRELEKIIA EKEERVSELR
710 720 730 740
HQLQSRQQIR SRRHPPTPPD PSGGLPRGPS EPPDRLSCDG SRVHLLYK
Length:748
Mass (Da):84,777
Last modified:March 1, 2003 - v1
Checksum:i991B3DB1749A8614
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK038844 mRNA. Translation: BAC30149.1.
UniGeneiMm.32191.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK038844 mRNA. Translation: BAC30149.1.
UniGeneiMm.32191.

3D structure databases

ProteinModelPortaliQ8CAF8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025338.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ8CAF8.
PeptideAtlasiQ8CAF8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1860139. Gabbr1.

Phylogenomic databases

eggNOGiKOG1055. Eukaryota.
ENOG410XNN1. LUCA.
HOVERGENiHBG051688.

Miscellaneous databases

ChiTaRSiGabbr1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiQ8CAF8.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR002455. GPCR3_GABA-B.
IPR000337. GPCR_3.
IPR017978. GPCR_3_C.
IPR002456. GPCR_3_GABA_rcpt_B1.
IPR028082. Peripla_BP_I.
[Graphical view]
PANTHERiPTHR10519. PTHR10519. 1 hit.
PTHR10519:SF42. PTHR10519:SF42. 1 hit.
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
[Graphical view]
PRINTSiPR01177. GABAB1RECPTR.
PR00248. GPCRMGR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HypothalamusImported.

Entry informationi

Entry nameiQ8CAF8_MOUSE
AccessioniPrimary (citable) accession number: Q8CAF8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.