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Q8CAF8

- Q8CAF8_MOUSE

UniProt

Q8CAF8 - Q8CAF8_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Gabbr1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. G-protein coupled GABA receptor activity Source: Ensembl
    2. protein binding Source: MGI

    GO - Biological processi

    1. adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Source: Ensembl
    2. gamma-aminobutyric acid signaling pathway Source: MGI

    Keywords - Molecular functioni

    G-protein coupled receptorSAAS annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Gabbr1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1860139. Gabbr1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. G-protein coupled receptor dimeric complex Source: MGI
    3. G-protein coupled receptor heterodimeric complex Source: Ensembl
    4. integral component of plasma membrane Source: Ensembl
    5. membrane Source: MGI
    6. postsynaptic membrane Source: MGI
    7. presynaptic membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiQ8CAF8.
    BgeeiQ8CAF8.
    GenevestigatoriQ8CAF8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CAF8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG051688.
    InParanoidiQ8CAF8.

    Family and domain databases

    InterProiIPR001828. ANF_lig-bd_rcpt.
    IPR002455. GPCR3_GABA-B.
    IPR000337. GPCR_3.
    IPR017978. GPCR_3_C.
    IPR002456. GPCR_3_GABA_rcpt_B1.
    IPR028082. Peripla_BP_I.
    [Graphical view]
    PANTHERiPTHR10519. PTHR10519. 1 hit.
    PfamiPF00003. 7tm_3. 1 hit.
    PF01094. ANF_receptor. 1 hit.
    [Graphical view]
    PRINTSiPR01177. GABAB1RECPTR.
    PR00248. GPCRMGR.
    SUPFAMiSSF53822. SSF53822. 1 hit.
    PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8CAF8-1 [UniParc]FASTAAdd to Basket

    « Hide

    IHHDSKCDPG QATKYLYELL YNDPIKIILM PGCSSVSTLV AEAARMWNLI    50
    VLSYGSSSPA LSNRQRFPTF FRTHPSATLH NPTRVKLFEK WGWKKIATIQ 100
    QTTEVFTSTL DDLEERVKEA GIEITFRQSF FSDPAVPVKN LKRQDARIIV 150
    GLFYETEARK VFCEVYKERL FGKKYVWFLI GWYADNWFKT YDPSINCTVE 200
    EMTEAVEGHI TTEIVMLNPA NTRSISNMTS QEFVEKLTKR LKRHPEETGG 250
    FQEAPLAYDA IWALALALNK TSGGGGRSGV RLEDFNYNNQ TITDQIYRAM 300
    NSSSFEGVSG HVVFDASGSR MAWTLIEQLQ GGSYKKIGYY DSTKDDLSWS 350
    KTDKWIGGSP PADQTLVIKT FRFLSQKLFI SVSVLSSLGI VLAVVCLSFN 400
    IYNSHVRYIQ NSQPNLNNLT AVGCSLALAA VFPLGLDGYH IGRSQFPFVC 450
    QARLWLLGLG FSLGYGSMFT KIWWVHTVFT KKEEKKEWRK TLEPWKLYAT 500
    VGLLVGMDIL TLAIWQIVDP LHRTIETFAK EEPKEDIDVS ILPQLEHCSS 550
    KKMNTWLGIF YGYKGLLLLL GIFLAYETKS VSTEKINDHR AVGMAIYNVA 600
    VLCLITAPVT MILSSQQDAA FAFASLAIVF SSYITLVVLF VPKMRRLITR 650
    GEWQSEAQDT MKTGSSTNNN EEEKSRLLEK ENRELEKIIA EKEERVSELR 700
    HQLQSRQQIR SRRHPPTPPD PSGGLPRGPS EPPDRLSCDG SRVHLLYK 748
    Length:748
    Mass (Da):84,777
    Last modified:March 1, 2003 - v1
    Checksum:i991B3DB1749A8614
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK038844 mRNA. Translation: BAC30149.1.
    UniGeneiMm.32191.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK038844 mRNA. Translation: BAC30149.1 .
    UniGenei Mm.32191.

    3D structure databases

    ProteinModelPortali Q8CAF8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1860139. Gabbr1.

    Phylogenomic databases

    HOVERGENi HBG051688.
    InParanoidi Q8CAF8.

    Miscellaneous databases

    ChiTaRSi GABBR1. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8CAF8.
    Bgeei Q8CAF8.
    Genevestigatori Q8CAF8.

    Family and domain databases

    InterProi IPR001828. ANF_lig-bd_rcpt.
    IPR002455. GPCR3_GABA-B.
    IPR000337. GPCR_3.
    IPR017978. GPCR_3_C.
    IPR002456. GPCR_3_GABA_rcpt_B1.
    IPR028082. Peripla_BP_I.
    [Graphical view ]
    PANTHERi PTHR10519. PTHR10519. 1 hit.
    Pfami PF00003. 7tm_3. 1 hit.
    PF01094. ANF_receptor. 1 hit.
    [Graphical view ]
    PRINTSi PR01177. GABAB1RECPTR.
    PR00248. GPCRMGR.
    SUPFAMi SSF53822. SSF53822. 1 hit.
    PROSITEi PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HypothalamusImported.

    Entry informationi

    Entry nameiQ8CAF8_MOUSE
    AccessioniPrimary (citable) accession number: Q8CAF8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)