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Q8CA63

- Q8CA63_MOUSE

UniProt

Q8CA63 - Q8CA63_MOUSE

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Protein
Submitted name:

Ephrin type-B receptor 1

Gene

Ephb1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. axon guidance receptor activity Source: MGI
  3. transmembrane-ephrin receptor activity Source: MGI

GO - Biological processi

  1. axon guidance Source: MGI
  2. camera-type eye morphogenesis Source: MGI
  3. central nervous system projection neuron axonogenesis Source: MGI
  4. cranial nerve development Source: MGI
  5. optic nerve morphogenesis Source: MGI
  6. retinal ganglion cell axon guidance Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin type-B receptor 1Imported
Gene namesi
Name:Ephb1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1096337. Ephb1.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: MGI
  2. cytoplasm Source: MGI
  3. integral component of plasma membrane Source: MGI
  4. membrane Source: MGI
  5. membrane raft Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ8CA63. baseline and differential.
GenevestigatoriQ8CA63.

Structurei

3D structure databases

ProteinModelPortaliQ8CA63.
SMRiQ8CA63. Positions 18-197.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118975.
HOVERGENiHBG062180.
KOiK05110.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.10. 1 hit.
InterProiIPR001090. Ephrin_rcpt_lig-bd_dom.
IPR003961. Fibronectin_type3.
IPR008979. Galactose-bd-like.
IPR009030. Growth_fac_rcpt_N_dom.
IPR013783. Ig-like_fold.
IPR001426. Tyr_kinase_rcpt_V_CS.
[Graphical view]
PfamiPF01404. Ephrin_lbd. 1 hit.
PF00041. fn3. 1 hit.
[Graphical view]
SMARTiSM00615. EPH_lbd. 1 hit.
SM00060. FN3. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEiPS51550. EPH_LBD. 1 hit.
PS50853. FN3. 1 hit.
PS00790. RECEPTOR_TYR_KIN_V_1. 1 hit.
PS00791. RECEPTOR_TYR_KIN_V_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CA63-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALDCLLLFL LASAVAAMEE TLMDTRTATA ELGWTANPAS GWEEVSGYDE
60 70 80 90 100
NLNTIRTYQV CNVFEPNQNN WLLTTFINRR GAHRIYTEMR FTVRDCSSLP
110 120 130 140 150
NVPGSCKETF NLYYYETDSV IATKKSAFWS EAPYLKVDTI AADESFSQVD
160 170 180 190 200
FGGRLMKVNT EVRSFGPLTR NGFYLAFQDY GACMSLLSVR VFFKKCPSIV
210 220 230 240 250
QNFAVFPETM TGAESTSLVI ARGTCIPNAE EVDVPIKLYC NGDGEWMVPI
260 270 280 290 300
GRCTCKPGYE PENSVACKAC PAGTFKASQE AEGCSHCPSN SRSPSEASPI
310 320 330 340 350
CTCRTGYYRA DFDPPEVACT SVPSGPRNVI SIVNETSIIL EWHPPRETGG
360 370 380 390 400
RDDVTYNIIC KKCRADRRSC SRCDDNVEFV PRQLGLTECR VSISSLWAHT
410 420 430 440 450
PYTFDIQAIN GVSSKSPFPP QHVSVNITTN QAGESGGFDV YICLCGWLFI

YLYVGS
Length:456
Mass (Da):50,470
Last modified:March 1, 2003 - v1
Checksum:iD110B1DF4E36C565
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC109247 Genomic DNA. No translation available.
AC132684 Genomic DNA. No translation available.
AC156635 Genomic DNA. No translation available.
CT025594 Genomic DNA. No translation available.
AK039530 mRNA. Translation: BAC30375.1.
RefSeqiNP_001161768.1. NM_001168296.1.
NP_775623.3. NM_173447.3.
UniGeneiMm.22897.

Genome annotation databases

EnsembliENSMUST00000149800; ENSMUSP00000139470; ENSMUSG00000032537.
GeneIDi270190.
KEGGimmu:270190.
UCSCiuc009rfo.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC109247 Genomic DNA. No translation available.
AC132684 Genomic DNA. No translation available.
AC156635 Genomic DNA. No translation available.
CT025594 Genomic DNA. No translation available.
AK039530 mRNA. Translation: BAC30375.1 .
RefSeqi NP_001161768.1. NM_001168296.1.
NP_775623.3. NM_173447.3.
UniGenei Mm.22897.

3D structure databases

ProteinModelPortali Q8CA63.
SMRi Q8CA63. Positions 18-197.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000149800 ; ENSMUSP00000139470 ; ENSMUSG00000032537 .
GeneIDi 270190.
KEGGi mmu:270190.
UCSCi uc009rfo.2. mouse.

Organism-specific databases

CTDi 2047.
MGIi MGI:1096337. Ephb1.

Phylogenomic databases

GeneTreei ENSGT00760000118975.
HOVERGENi HBG062180.
KOi K05110.

Miscellaneous databases

NextBioi 393293.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi Q8CA63. baseline and differential.
Genevestigatori Q8CA63.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.10. 1 hit.
InterProi IPR001090. Ephrin_rcpt_lig-bd_dom.
IPR003961. Fibronectin_type3.
IPR008979. Galactose-bd-like.
IPR009030. Growth_fac_rcpt_N_dom.
IPR013783. Ig-like_fold.
IPR001426. Tyr_kinase_rcpt_V_CS.
[Graphical view ]
Pfami PF01404. Ephrin_lbd. 1 hit.
PF00041. fn3. 1 hit.
[Graphical view ]
SMARTi SM00615. EPH_lbd. 1 hit.
SM00060. FN3. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEi PS51550. EPH_LBD. 1 hit.
PS50853. FN3. 1 hit.
PS00790. RECEPTOR_TYR_KIN_V_1. 1 hit.
PS00791. RECEPTOR_TYR_KIN_V_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal cordImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8CA63_MOUSE
AccessioniPrimary (citable) accession number: Q8CA63
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3