Q8CA63 (Q8CA63_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAC30375.1

Gene names

Name:

Ephb1 MGI 1096337

Organism

Mus musculus (Mouse) EMBL BAC30375.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	456 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	camera-type eye morphogenesis Inferred from mutant phenotype PubMed 12971893. Source: MGI central nervous system projection neuron axonogenesis Inferred from direct assay PubMed 12971893. Source: MGI optic nerve morphogenesis Inferred from mutant phenotype PubMed 12971893. Source: MGI retinal ganglion cell axon guidance Inferred from direct assay PubMed 12971893. Source: MGI
Cellular_component	axon Inferred from direct assay PubMed 16701205. Source: MGI cytoplasm Inferred from direct assay PubMed 12093895. Source: MGI integral to plasma membrane Traceable author statement PubMed 11532925. Source: MGI membrane raft Inferred from direct assay PubMed 15502157. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro axon guidance receptor activity Inferred from direct assay PubMed 11532925. Source: MGI transmembrane-ephrin receptor activity Traceable author statement PubMed 11532925. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8CA63 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: D110B1DF4E36C565	FASTA	456	50,470
	10 20 30 40 50 60 MALDCLLLFL LASAVAAMEE TLMDTRTATA ELGWTANPAS GWEEVSGYDE NLNTIRTYQV 70 80 90 100 110 120 CNVFEPNQNN WLLTTFINRR GAHRIYTEMR FTVRDCSSLP NVPGSCKETF NLYYYETDSV 130 140 150 160 170 180 IATKKSAFWS EAPYLKVDTI AADESFSQVD FGGRLMKVNT EVRSFGPLTR NGFYLAFQDY 190 200 210 220 230 240 GACMSLLSVR VFFKKCPSIV QNFAVFPETM TGAESTSLVI ARGTCIPNAE EVDVPIKLYC 250 260 270 280 290 300 NGDGEWMVPI GRCTCKPGYE PENSVACKAC PAGTFKASQE AEGCSHCPSN SRSPSEASPI 310 320 330 340 350 360 CTCRTGYYRA DFDPPEVACT SVPSGPRNVI SIVNETSIIL EWHPPRETGG RDDVTYNIIC 370 380 390 400 410 420 KKCRADRRSC SRCDDNVEFV PRQLGLTECR VSISSLWAHT PYTFDIQAIN GVSSKSPFPP 430 440 450 QHVSVNITTN QAGESGGFDV YICLCGWLFI YLYVGS

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
[5]	Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
[6]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30375.1. Tissue: Spinal cord EMBL BAC30375.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK039530 mRNA. Translation: BAC30375.1.
IPI	IPI00808241.
RefSeq	NP_001161768.1. NM_001168296.1. NP_775623.3. NM_173447.3.
UniGene	Mm.22897.
3D structure databases
HSSP	HSSP built from PDB template 1NUK based on UniProtKB P54763.
ProteinModelPortal	Q8CA63.
SMR	Q8CA63. Positions 18-197.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	270190.
KEGG	mmu:270190.
UCSC	uc009rfo.2. mouse.
Organism-specific databases
CTD	2047.
MGI	MGI:1096337. Ephb1.
Phylogenomic databases
HOVERGEN	HBG062180.
InParanoid	Q8CA63.
KO	K05110.
Gene expression databases
Genevestigator	Q8CA63.
Family and domain databases
Gene3D	2.60.40.10. 1 hit.
InterPro	IPR001090. Ephrin_rcpt_lig-bd_dom. IPR003961. Fibronectin_type3. IPR008979. Galactose-bd-like. IPR009030. Growth_fac_rcpt. IPR013783. Ig-like_fold. IPR001426. Tyr_kinase_rcpt_V_CS. [Graphical view]
Pfam	PF01404. Ephrin_lbd. 1 hit. PF00041. fn3. 1 hit. [Graphical view]
SMART	SM00615. EPH_lbd. 1 hit. SM00060. FN3. 1 hit. [Graphical view]
SUPFAM	SSF49265. FN_III-like. 1 hit. SSF49785. Gal_bind_like. 1 hit. SSF57184. Grow_fac_recept. 1 hit.
PROSITE	PS51550. EPH_LBD. 1 hit. PS50853. FN3. 1 hit. PS00790. RECEPTOR_TYR_KIN_V_1. 1 hit. PS00791. RECEPTOR_TYR_KIN_V_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	393293.
SOURCE	Search...

Entry information

Entry name

Q8CA63_MOUSE

Accession

Primary (citable) accession number: Q8CA63

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	April 3, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)