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Protein
Submitted name:

Ephrin type-B receptor 1

Gene

Ephb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin type-B receptor 1Imported
Gene namesi
Name:Ephb1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1096337. Ephb1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500878427618 – 456Sequence analysisAdd BLAST439

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035129.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 201Eph LBD (Eph ligand-binding)InterPro annotationAdd BLAST183
Domaini322 – 432Fibronectin type-IIIInterPro annotationAdd BLAST111

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0196. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00760000118975.
HOVERGENiHBG062180.
KOiK05110.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.120.260. 1 hit.
2.60.40.10. 1 hit.
InterProiIPR001090. Ephrin_rcpt_lig-bd_dom.
IPR003961. FN3_dom.
IPR008979. Galactose-bd-like.
IPR009030. Growth_fac_rcpt_.
IPR013783. Ig-like_fold.
IPR011641. Tyr-kin_ephrin_A/B_rcpt-like.
IPR001426. Tyr_kinase_rcpt_V_CS.
[Graphical view]
PfamiPF01404. Ephrin_lbd. 1 hit.
PF00041. fn3. 1 hit.
[Graphical view]
SMARTiSM00615. EPH_lbd. 1 hit.
SM01411. Ephrin_rec_like. 1 hit.
SM00060. FN3. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEiPS51550. EPH_LBD. 1 hit.
PS50853. FN3. 1 hit.
PS00790. RECEPTOR_TYR_KIN_V_1. 1 hit.
PS00791. RECEPTOR_TYR_KIN_V_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CA63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALDCLLLFL LASAVAAMEE TLMDTRTATA ELGWTANPAS GWEEVSGYDE
60 70 80 90 100
NLNTIRTYQV CNVFEPNQNN WLLTTFINRR GAHRIYTEMR FTVRDCSSLP
110 120 130 140 150
NVPGSCKETF NLYYYETDSV IATKKSAFWS EAPYLKVDTI AADESFSQVD
160 170 180 190 200
FGGRLMKVNT EVRSFGPLTR NGFYLAFQDY GACMSLLSVR VFFKKCPSIV
210 220 230 240 250
QNFAVFPETM TGAESTSLVI ARGTCIPNAE EVDVPIKLYC NGDGEWMVPI
260 270 280 290 300
GRCTCKPGYE PENSVACKAC PAGTFKASQE AEGCSHCPSN SRSPSEASPI
310 320 330 340 350
CTCRTGYYRA DFDPPEVACT SVPSGPRNVI SIVNETSIIL EWHPPRETGG
360 370 380 390 400
RDDVTYNIIC KKCRADRRSC SRCDDNVEFV PRQLGLTECR VSISSLWAHT
410 420 430 440 450
PYTFDIQAIN GVSSKSPFPP QHVSVNITTN QAGESGGFDV YICLCGWLFI

YLYVGS
Length:456
Mass (Da):50,470
Last modified:March 1, 2003 - v1
Checksum:iD110B1DF4E36C565
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109247 Genomic DNA. No translation available.
AC132684 Genomic DNA. No translation available.
AC156635 Genomic DNA. No translation available.
CT025594 Genomic DNA. No translation available.
AK039530 mRNA. Translation: BAC30375.1.
RefSeqiNP_001161768.1. NM_001168296.1.
NP_775623.3. NM_173447.3.
UniGeneiMm.22897.

Genome annotation databases

EnsembliENSMUST00000149800; ENSMUSP00000139470; ENSMUSG00000032537.
GeneIDi270190.
KEGGimmu:270190.
UCSCiuc009rfo.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109247 Genomic DNA. No translation available.
AC132684 Genomic DNA. No translation available.
AC156635 Genomic DNA. No translation available.
CT025594 Genomic DNA. No translation available.
AK039530 mRNA. Translation: BAC30375.1.
RefSeqiNP_001161768.1. NM_001168296.1.
NP_775623.3. NM_173447.3.
UniGeneiMm.22897.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035129.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000149800; ENSMUSP00000139470; ENSMUSG00000032537.
GeneIDi270190.
KEGGimmu:270190.
UCSCiuc009rfo.2. mouse.

Organism-specific databases

CTDi2047.
MGIiMGI:1096337. Ephb1.

Phylogenomic databases

eggNOGiKOG0196. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00760000118975.
HOVERGENiHBG062180.
KOiK05110.

Miscellaneous databases

ChiTaRSiEphb1. mouse.
SOURCEiSearch...

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.120.260. 1 hit.
2.60.40.10. 1 hit.
InterProiIPR001090. Ephrin_rcpt_lig-bd_dom.
IPR003961. FN3_dom.
IPR008979. Galactose-bd-like.
IPR009030. Growth_fac_rcpt_.
IPR013783. Ig-like_fold.
IPR011641. Tyr-kin_ephrin_A/B_rcpt-like.
IPR001426. Tyr_kinase_rcpt_V_CS.
[Graphical view]
PfamiPF01404. Ephrin_lbd. 1 hit.
PF00041. fn3. 1 hit.
[Graphical view]
SMARTiSM00615. EPH_lbd. 1 hit.
SM01411. Ephrin_rec_like. 1 hit.
SM00060. FN3. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF57184. SSF57184. 2 hits.
PROSITEiPS51550. EPH_LBD. 1 hit.
PS50853. FN3. 1 hit.
PS00790. RECEPTOR_TYR_KIN_V_1. 1 hit.
PS00791. RECEPTOR_TYR_KIN_V_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8CA63_MOUSE
AccessioniPrimary (citable) accession number: Q8CA63
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.