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Q8C9W5

- Q8C9W5_MOUSE

UniProt

Q8C9W5 - Q8C9W5_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Erap1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. aminopeptidase activity Source: MGI
  2. metalloexopeptidase activity Source: Ensembl
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. membrane protein ectodomain proteolysis Source: Ensembl
  2. positive regulation of angiogenesis Source: MGI
  3. response to bacterium Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Erap1Imported
Synonyms:Arts1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1933403. Erap1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. extracellular space Source: Ensembl
  3. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ8C9W5.
ExpressionAtlasiQ8C9W5. baseline and differential.
GenevestigatoriQ8C9W5.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022070.

Structurei

3D structure databases

ProteinModelPortaliQ8C9W5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG108296.

Family and domain databases

InterProiIPR024571. ERAP1-like_C_dom.
IPR001930. Peptidase_M1.
IPR014782. Peptidase_M1_N.
[Graphical view]
PANTHERiPTHR11533. PTHR11533. 1 hit.
PfamiPF11838. ERAP1_C. 1 hit.
PF01433. Peptidase_M1. 1 hit.
[Graphical view]
PRINTSiPR00756. ALADIPTASE.

Sequencei

Sequence statusi: Fragment.

Q8C9W5 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
AFIISDFKSV SKMTKSGVKV SVYAVPDKIN QADYALDAAV TLLEFYEDYF
60 70 80 90 100
NIPYPLPKQD LAAIPDFQSG AMENWGLTTY RESSLLYDKE KSSASSKLGI
110 120 130 140 150
TMIVSHELAH QWFGNLVTME WWNDLWLNEG FAKFMEFVSV TVTHPELKVE
160 170 180 190 200
DYFFGKCFNA MEVDALNSSH PVSTPVENPA QIREMFDDVS YEKGACILNM
210 220 230 240 250
LRDYLSADTF KRGIVQYLQK YSYKNTKNED LWNSMMHICP TDGTQTMDGF
260 270 280 290 300
CSRSQHSSST SHWRQEVVDV KTMMNTWTLQ KGFPLITITV SGRNVHMKQE
310 320 330 340 350
HYMKGSERFP ETGYLWHVPL TFITSKSDSV QRFLLKTKTD VLILPEAVQW
360 370 380 390 400
IKFNVGMNGY YIVHYADDGW ASLSGLLKEA HTTISSNDRA SLINNAFQLV
410 420 430 440 450
SIEKLSIEKA LDLTLYLKNE TEIMPIFQAL NELIPMYKLM EKRDMIEVET
460 470 480 490 500
QFKDFLLKLL KDLIDKQTWT DEGSVSERML RSQLLLLACV RNYQPCVQRA
510 520 530 540 550
ERYFREWKSS NGNMSIPIDV TLAVFAVGAQ NTEGWDFLYS KYQSSLSSTE
560 570 580 590 600
KSQIEFSLCT SKDPEKLQWL LDQSFKGEII KTQEFPHILT LIGRNPVGYP
610 620 630 640 650
LAWKFLRENW NKLVQKFELG SSSIAHMVMG TTDQFSTRAR LEEVKGFFSS
660 670 680 690
LKENGSQLRC VQQTIETIEE NIRWMDKNFD KIRLWLQKEK PELL
Length:694
Mass (Da):80,187
Last modified:March 1, 2003 - v1
Checksum:iB1EA3680BBC60BCB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK040350 mRNA. Translation: BAC30569.1.
UniGeneiMm.83526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK040350 mRNA. Translation: BAC30569.1 .
UniGenei Mm.83526.

3D structure databases

ProteinModelPortali Q8C9W5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000022070.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1933403. Erap1.

Phylogenomic databases

HOVERGENi HBG108296.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q8C9W5.
ExpressionAtlasi Q8C9W5. baseline and differential.
Genevestigatori Q8C9W5.

Family and domain databases

InterProi IPR024571. ERAP1-like_C_dom.
IPR001930. Peptidase_M1.
IPR014782. Peptidase_M1_N.
[Graphical view ]
PANTHERi PTHR11533. PTHR11533. 1 hit.
Pfami PF11838. ERAP1_C. 1 hit.
PF01433. Peptidase_M1. 1 hit.
[Graphical view ]
PRINTSi PR00756. ALADIPTASE.
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.

Entry informationi

Entry nameiQ8C9W5_MOUSE
AccessioniPrimary (citable) accession number: Q8C9W5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)