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Q8C8N0

- Q8C8N0_MOUSE

UniProt

Q8C8N0 - Q8C8N0_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Itpr1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Source: MGI
    2. phosphatidylinositol binding Source: MGI
    3. protein binding Source: MGI

    GO - Biological processi

    1. calcium ion transport Source: MGI
    2. endoplasmic reticulum calcium ion homeostasis Source: MGI
    3. inositol phosphate-mediated signaling Source: GOC
    4. post-embryonic development Source: MGI
    5. response to hypoxia Source: Ensembl
    6. voluntary musculoskeletal movement Source: MGI

    Keywords - Molecular functioni

    Ion channelUniRule annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Itpr1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:96623. Itpr1.

    Subcellular locationi

    GO - Cellular componenti

    1. calcineurin complex Source: MGI
    2. cytoplasm Source: MGI
    3. endoplasmic reticulum Source: MGI
    4. endoplasmic reticulum membrane Source: MGI
    5. integral component of membrane Source: UniProtKB-KW
    6. nuclear envelope Source: MGI
    7. nuclear inner membrane Source: MGI
    8. nucleolus Source: MGI
    9. platelet dense granule membrane Source: Ensembl
    10. platelet dense tubular network Source: Ensembl
    11. postsynaptic density Source: MGI
    12. protein complex Source: MGI
    13. sarcoplasmic reticulum Source: MGI

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiQ8C8N0.
    BgeeiQ8C8N0.
    GenevestigatoriQ8C8N0.

    Family & Domainsi

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG106626.
    InParanoidiQ8C8N0.
    KOiK04958.

    Family and domain databases

    InterProiIPR005821. Ion_trans_dom.
    IPR015925. Ryanodine_recept-rel.
    [Graphical view]
    PANTHERiPTHR13715. PTHR13715. 1 hit.
    PfamiPF00520. Ion_trans. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8C8N0-1 [UniParc]FASTAAdd to Basket

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    NLLVAFFYPF KGVRGGTLEP HWSGLLWTAM LISLAIVIAL PKPHGIRALI    50
    ASTILRLIFS VGLQPTLFLL GAFNVCNKII FLMSFVGNCG TFTRGYRAMV 100
    LDVEFLYHLL YLLICAMGLF VHEFFYSLLL FDLVYREETL LNVIKSVTRN 150
    GRSIILTAVL ALILVYLFSI VGYLFFKDDF ILEVDRLPNE TAVPETGESL 200
    ANDFLYSDVC RVETGENCTS PAPKEELLPA EETEQDKEHT CETLLMCIVT 250
    VLSHGLRSGG GVGDVLRKPS KEEPLFAARV IYDLLFFFMV IIIVLNLIFG 300
    VIIDTFADLR SEKQKKEEIL KTTCFICGLE RDKFDNKTVT FEEHIKEEHN 350
    MWHYLCFIVL VKVKDSTEYT GPESYVAEMI RERNLDWFPR MRAMSLVSSD 400
    SEGEQNELRN LQEKLESTMK LVTNLSGQLS ELKDQMTEQR KQKQRIGLLG 450
    HPPHMNVNPQ QPA 463
    Length:463
    Mass (Da):52,762
    Last modified:March 1, 2003 - v1
    Checksum:iB517A935952DEA3F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK044776 mRNA. Translation: BAC32085.1.
    RefSeqiNP_034715.3. NM_010585.5.
    UniGeneiMm.227912.

    Genome annotation databases

    GeneIDi16438.
    KEGGimmu:16438.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK044776 mRNA. Translation: BAC32085.1 .
    RefSeqi NP_034715.3. NM_010585.5.
    UniGenei Mm.227912.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 16438.
    KEGGi mmu:16438.

    Organism-specific databases

    CTDi 3708.
    MGIi MGI:96623. Itpr1.

    Phylogenomic databases

    HOVERGENi HBG106626.
    InParanoidi Q8C8N0.
    KOi K04958.

    Miscellaneous databases

    ChiTaRSi ITPR1. mouse.
    NextBioi 289681.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8C8N0.
    Bgeei Q8C8N0.
    Genevestigatori Q8C8N0.

    Family and domain databases

    InterProi IPR005821. Ion_trans_dom.
    IPR015925. Ryanodine_recept-rel.
    [Graphical view ]
    PANTHERi PTHR13715. PTHR13715. 1 hit.
    Pfami PF00520. Ion_trans. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: RetinaImported.

    Entry informationi

    Entry nameiQ8C8N0_MOUSE
    AccessioniPrimary (citable) accession number: Q8C8N0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)