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Q8C8N0 (Q8C8N0_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Itpr1 MGI 96623
OrganismMus musculus (Mouse) EMBL BAC32085.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length463 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU003378
   Molecular functionIon channel RuleBase RU003378
Gene Ontology (GO)
   Biological_processcalcium ion transport

Inferred from direct assay PubMed 16014380. Source: MGI

endoplasmic reticulum calcium ion homeostasis

Inferred from genetic interaction PubMed 15613488. Source: MGI

inositol phosphate-mediated signaling

Inferred from direct assay PubMed 17327232. Source: GOC

post-embryonic development

Inferred from mutant phenotype PubMed 17590087. Source: MGI

response to hypoxia

Inferred from electronic annotation. Source: Ensembl

voluntary musculoskeletal movement

Inferred from mutant phenotype PubMed 17590087. Source: MGI

   Cellular_componentcalcineurin complex

Inferred from direct assay PubMed 12617961. Source: MGI

cytoplasm

Inferred from direct assay PubMed 9858485. Source: MGI

endoplasmic reticulum

Traceable author statement PubMed 1648733. Source: MGI

endoplasmic reticulum membrane

Inferred from direct assay PubMed 15613488. Source: MGI

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

nuclear envelope

Inferred from direct assay PubMed 16014380. Source: MGI

nuclear inner membrane

Inferred from direct assay PubMed 16014380. Source: MGI

nucleolus

Inferred from direct assay PubMed 16014380. Source: MGI

platelet dense granule membrane

Inferred from electronic annotation. Source: Ensembl

platelet dense tubular network

Inferred from electronic annotation. Source: Ensembl

postsynaptic density

Inferred from direct assay PubMed 15579147. Source: MGI

protein complex

Inferred from physical interaction PubMed 17416589. Source: MGI

sarcoplasmic reticulum

Inferred from direct assay PubMed 16014380. Source: MGI

   Molecular_functioninositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

Inferred from direct assay PubMed 17327232. Source: MGI

phosphatidylinositol binding

Inferred from direct assay PubMed 17327232PubMed 8663526. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAC32085.1

Sequences

Sequence LengthMass (Da)Tools
Q8C8N0 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: B517A935952DEA3F

FASTA46352,762
        10         20         30         40         50         60 
NLLVAFFYPF KGVRGGTLEP HWSGLLWTAM LISLAIVIAL PKPHGIRALI ASTILRLIFS 

        70         80         90        100        110        120 
VGLQPTLFLL GAFNVCNKII FLMSFVGNCG TFTRGYRAMV LDVEFLYHLL YLLICAMGLF 

       130        140        150        160        170        180 
VHEFFYSLLL FDLVYREETL LNVIKSVTRN GRSIILTAVL ALILVYLFSI VGYLFFKDDF 

       190        200        210        220        230        240 
ILEVDRLPNE TAVPETGESL ANDFLYSDVC RVETGENCTS PAPKEELLPA EETEQDKEHT 

       250        260        270        280        290        300 
CETLLMCIVT VLSHGLRSGG GVGDVLRKPS KEEPLFAARV IYDLLFFFMV IIIVLNLIFG 

       310        320        330        340        350        360 
VIIDTFADLR SEKQKKEEIL KTTCFICGLE RDKFDNKTVT FEEHIKEEHN MWHYLCFIVL 

       370        380        390        400        410        420 
VKVKDSTEYT GPESYVAEMI RERNLDWFPR MRAMSLVSSD SEGEQNELRN LQEKLESTMK 

       430        440        450        460 
LVTNLSGQLS ELKDQMTEQR KQKQRIGLLG HPPHMNVNPQ QPA 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
[5]Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. expand/collapse author list , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC32085.1.
Tissue: Retina EMBL BAC32085.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK044776 mRNA. Translation: BAC32085.1.
RefSeqNP_034715.3. NM_010585.5.
UniGeneMm.227912.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID16438.
KEGGmmu:16438.

Organism-specific databases

CTD3708.
MGIMGI:96623. Itpr1.

Phylogenomic databases

HOVERGENHBG106626.
InParanoidQ8C8N0.
KOK04958.

Gene expression databases

ArrayExpressQ8C8N0.
BgeeQ8C8N0.
GenevestigatorQ8C8N0.

Family and domain databases

InterProIPR005821. Ion_trans_dom.
IPR015925. Ryanodine_recept-rel.
[Graphical view]
PANTHERPTHR13715. PTHR13715. 1 hit.
PfamPF00520. Ion_trans. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSITPR1. mouse.
NextBio289681.
SOURCESearch...

Entry information

Entry nameQ8C8N0_MOUSE
AccessionPrimary (citable) accession number: Q8C8N0
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)