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Protein
Submitted name:

Interleukin-1 receptor type 1

Gene

Il1r1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-1 receptor type 1Imported
Gene namesi
Name:Il1r1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:96545. Il1r1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei337 – 35923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence analysisAdd
BLAST
Chaini17 – 573557Sequence analysisPRO_5007927456Add
BLAST

Expressioni

Gene expression databases

BgeeiENSMUSG00000026072.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027241.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini43 – 11270Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini118 – 21093Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini226 – 326101Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini383 – 541159TIRInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IQBC. Eukaryota.
ENOG410Z3W1. LUCA.
GeneTreeiENSGT00760000119071.
HOVERGENiHBG052103.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004076. IL-1_rcpt_I-typ.
IPR004074. IL-1_rcpt_I/II-typ.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF07679. I-set. 1 hit.
PF13895. Ig_2. 1 hit.
PF01582. TIR. 1 hit.
[Graphical view]
PRINTSiPR01538. INTRLEUKN1R1.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 3 hits.
PS50104. TIR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8C833-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLLGLICL MVPLLSLEID VCTEYPNQIV LFLSVNEIDI RKCPLTPNKM
60 70 80 90 100
HGDTIIWYKN DSKTPISADR DSRIHQQNEH LWFVPAKVED SGYYYCIVRN
110 120 130 140 150
STYCLKTKVT VTVLENDPGL CYSTQATFPQ RLHIAGDGSL VCPYVSYFKD
160 170 180 190 200
ENNELPEVQW YKNCKPLLLD NVSFFGVKDK LLVRNVAEEH RGDYICRMSY
210 220 230 240 250
TFRGKQYPVT RVIQFITIDE NKRDRPVILS PRNETIEADP GSMIQLICNV
260 270 280 290 300
TGQFSDLVYW KWNGSEIEWN DPFLAEDYQF VEHPSTKRKY TLITTLNISE
310 320 330 340 350
VKSQFYRYPF ICVVKNTNIF ESAHVQLIYP VPDFKNYLIG GFIILTATIV
360 370 380 390 400
CCVCIYKVFK VDIVLWYRDS CSGFLPSKAS DGKTYDAYIL YPKTLGEGSF
410 420 430 440 450
SDLDTFVFKL LPEVLEGQFG YKLFIYGRDD YVGEDTIEVT NENVKKSRRL
460 470 480 490 500
IIILVRDMGG FSWLGQSSEE QIAIYNALIQ EGIKIVLLEL EKIQDYEKMP
510 520 530 540 550
DSIQFIKQKH GVICWSGDFQ ERPQSAKTRF WKNLRYQMPA QRRSPLSKHR
560 570
LLTLDPVRDT KEKLPAATHL PLG
Length:573
Mass (Da):66,323
Last modified:March 1, 2003 - v1
Checksum:i3B750CBD0F49C14D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135085 Genomic DNA. No translation available.
AC167168 Genomic DNA. No translation available.
AK048550 mRNA. Translation: BAC33372.1.
RefSeqiNP_001116854.1. NM_001123382.1.
XP_006495777.1. XM_006495714.2.
XP_006495778.1. XM_006495715.2.
XP_006495779.1. XM_006495716.2.
XP_006495780.1. XM_006495717.2.
XP_006495781.1. XM_006495718.2.
XP_006495782.1. XM_006495719.2.
XP_006495783.1. XM_006495720.2.
XP_006495784.1. XM_006495721.2.
XP_006495785.1. XM_006495722.2.
XP_006495786.1. XM_006495723.2.
XP_011236738.1. XM_011238436.1.
UniGeneiMm.896.

Genome annotation databases

EnsembliENSMUST00000114795; ENSMUSP00000110443; ENSMUSG00000026072.
GeneIDi16177.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135085 Genomic DNA. No translation available.
AC167168 Genomic DNA. No translation available.
AK048550 mRNA. Translation: BAC33372.1.
RefSeqiNP_001116854.1. NM_001123382.1.
XP_006495777.1. XM_006495714.2.
XP_006495778.1. XM_006495715.2.
XP_006495779.1. XM_006495716.2.
XP_006495780.1. XM_006495717.2.
XP_006495781.1. XM_006495718.2.
XP_006495782.1. XM_006495719.2.
XP_006495783.1. XM_006495720.2.
XP_006495784.1. XM_006495721.2.
XP_006495785.1. XM_006495722.2.
XP_006495786.1. XM_006495723.2.
XP_011236738.1. XM_011238436.1.
UniGeneiMm.896.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027241.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000114795; ENSMUSP00000110443; ENSMUSG00000026072.
GeneIDi16177.

Organism-specific databases

CTDi3554.
MGIiMGI:96545. Il1r1.

Phylogenomic databases

eggNOGiENOG410IQBC. Eukaryota.
ENOG410Z3W1. LUCA.
GeneTreeiENSGT00760000119071.
HOVERGENiHBG052103.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026072.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004076. IL-1_rcpt_I-typ.
IPR004074. IL-1_rcpt_I/II-typ.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF07679. I-set. 1 hit.
PF13895. Ig_2. 1 hit.
PF01582. TIR. 1 hit.
[Graphical view]
PRINTSiPR01538. INTRLEUKN1R1.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 3 hits.
PS50104. TIR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8C833_MOUSE
AccessioniPrimary (citable) accession number: Q8C833
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.