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Protein

Zinc finger SWIM domain-containing protein 4

Gene

Zswim4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri134 – 17138SWIM-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger SWIM domain-containing protein 4
Gene namesi
Name:Zswim4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2443726. Zswim4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11011101Zinc finger SWIM domain-containing protein 4PRO_0000223102Add
BLAST

Proteomic databases

PaxDbiQ8C7B8.
PRIDEiQ8C7B8.

PTM databases

iPTMnetiQ8C7B8.
PhosphoSiteiQ8C7B8.

Expressioni

Gene expression databases

BgeeiQ8C7B8.
CleanExiMM_ZSWIM4.
GenevisibleiQ8C7B8. MM.

Interactioni

Protein-protein interaction databases

BioGridi229300. 2 interactions.
STRINGi10090.ENSMUSP00000040078.

Family & Domainsi

Sequence similaritiesi

Contains 1 SWIM-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri134 – 17138SWIM-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3615. Eukaryota.
ENOG410XPZG. LUCA.
GeneTreeiENSGT00390000012572.
HOGENOMiHOG000231419.
HOVERGENiHBG058098.
InParanoidiQ8C7B8.
OMAiMRMTLNT.
OrthoDBiEOG74J970.
PhylomeDBiQ8C7B8.
TreeFamiTF324881.

Family and domain databases

InterProiIPR007527. Znf_SWIM.
[Graphical view]
PROSITEiPS50966. ZF_SWIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8C7B8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPPAAKRSR GCPAGDEPGT GARRSRPEPL LDLSAKRVAE SWAFEQVEER
60 70 80 90 100
FSRVPEPVQK RIVFWSFPRS EREICMYSSL GYQPPEGEQD TRVPFTRGLH
110 120 130 140 150
LLQSGAVDRV LQVGFHLSGN IREVGGPGEP EHLYHVSISF DRCKITSVSC
160 170 180 190 200
GCDNRDLFYC AHVVALSLYR IRHARQVELR LPISETLSQM NRDQLQKFVQ
210 220 230 240 250
YLISAHHTEV LPTAQRLADE ILLLGSEINL VHGAPDPTAG AGTEDANCWH
260 270 280 290 300
LDEEQIQEQV KQLLSNGGHY GASQQLRSMF SKVREMLRAR DSNGARMLIL
310 320 330 340 350
MTEQFLQDPR LALWRQQGAG MTDKCRQLWD ELGALWVCVI LSPHCKPDER
360 370 380 390 400
SGWLQLLGTW DKLDVCPLEE GNYSLDIPSL QPALTSRTGS EDEEEVTAAS
410 420 430 440 450
PRRTVFSRAL QAGELHWNDS HLQRILASDS CGPTLTGSMG SDKPTFDPQG
460 470 480 490 500
HPIWLGEPFP TACARVDTLR AHGYPHKALR LACAIINTLR LQRRHQLESY
510 520 530 540 550
KQQKKELLQK GATGVTSTEG WVGHPLDPIG CLCRALLEAC RLEEEPHSLF
560 570 580 590 600
PDSAPEKRKL AYQHVLVPGS PGESYLALAL EVALLGLGQQ RALPEGLYAQ
610 620 630 640 650
DKVVRNEEQL LALLEEVELD ERLVQVLRKQ AGLLLEGGPF SGFGEVIFRE
660 670 680 690 700
SVPMHTCARY LFTALLPHDP DLAFRLALRA MRLPVLETTF PAGESHPNPL
710 720 730 740 750
DSIMSNRFPR WFILGHLETR QCELASTMLT AAKGDTKWLH AVLGSVQQNI
760 770 780 790 800
HSPALLFKLA QDACKTATPA SAPPDTVLLG IALELGLQVM RMTLNTMTWR
810 820 830 840 850
RREMVRWLVS CATEIGPPAL MSIMKNWYSL FTPVEAVTIV AVTGTTHATL
860 870 880 890 900
LRLQLDTAGR EELWACARTL ALQCAMKDPQ NCALPALTLC EKNHAAFEAA
910 920 930 940 950
YQIVLDAAAG GLGHAHLFTV ARYMEHRGLP LRAYKLATLA LAQLSIAFNQ
960 970 980 990 1000
DSHPAVNDVL WACSLSHSLG RHELSAIVPL IIRSIHCAPM LSDILRRWTL
1010 1020 1030 1040 1050
SAPGLGPLGA RRATKPLGTD RAPLCQLLDA AVAAYITTSH SRLTHISPRH
1060 1070 1080 1090 1100
YGDFIEFLGK ARETFLLAPD GHLQFAQFLE NLKQTYKGKK KLMLLVRERF

G
Length:1,101
Mass (Da):122,445
Last modified:January 16, 2004 - v2
Checksum:iC90F39F4A2DBEFD4
GO

Sequence cautioni

The sequence BAC35466.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti26 – 261R → L in BAC35466 (PubMed:16141072).Curated
Sequence conflicti984 – 9841S → G in BAC34867 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052168 mRNA. Translation: BAC34867.1.
AK053663 mRNA. Translation: BAC35466.1. Different initiation.
BC058080 mRNA. Translation: AAH58080.1.
CCDSiCCDS22471.1.
RefSeqiNP_766091.2. NM_172503.3.
UniGeneiMm.117094.

Genome annotation databases

EnsembliENSMUST00000039480; ENSMUSP00000040078; ENSMUSG00000035671.
GeneIDi212168.
KEGGimmu:212168.
UCSCiuc009mmg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052168 mRNA. Translation: BAC34867.1.
AK053663 mRNA. Translation: BAC35466.1. Different initiation.
BC058080 mRNA. Translation: AAH58080.1.
CCDSiCCDS22471.1.
RefSeqiNP_766091.2. NM_172503.3.
UniGeneiMm.117094.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi229300. 2 interactions.
STRINGi10090.ENSMUSP00000040078.

PTM databases

iPTMnetiQ8C7B8.
PhosphoSiteiQ8C7B8.

Proteomic databases

PaxDbiQ8C7B8.
PRIDEiQ8C7B8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000039480; ENSMUSP00000040078; ENSMUSG00000035671.
GeneIDi212168.
KEGGimmu:212168.
UCSCiuc009mmg.1. mouse.

Organism-specific databases

CTDi65249.
MGIiMGI:2443726. Zswim4.

Phylogenomic databases

eggNOGiKOG3615. Eukaryota.
ENOG410XPZG. LUCA.
GeneTreeiENSGT00390000012572.
HOGENOMiHOG000231419.
HOVERGENiHBG058098.
InParanoidiQ8C7B8.
OMAiMRMTLNT.
OrthoDBiEOG74J970.
PhylomeDBiQ8C7B8.
TreeFamiTF324881.

Miscellaneous databases

ChiTaRSiZswim4. mouse.
NextBioi373494.
PROiQ8C7B8.
SOURCEiSearch...

Gene expression databases

BgeeiQ8C7B8.
CleanExiMM_ZSWIM4.
GenevisibleiQ8C7B8. MM.

Family and domain databases

InterProiIPR007527. Znf_SWIM.
[Graphical view]
PROSITEiPS50966. ZF_SWIM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Eye and Heart.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Brain.

Entry informationi

Entry nameiZSWM4_MOUSE
AccessioniPrimary (citable) accession number: Q8C7B8
Secondary accession number(s): Q8BPN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: January 16, 2004
Last modified: January 20, 2016
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.