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Protein
Submitted name:

Putative uncharacterized protein

Gene

Mitf

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:MitfImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104554. Mitf.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ8C6Y4.

Expressioni

Gene expression databases

BgeeiQ8C6Y4.
GenevisibleiQ8C6Y4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000044938.

Structurei

3D structure databases

ProteinModelPortaliQ8C6Y4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini295 – 34854BHLH (basic helix-loop-helix)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili44 – 7229Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1318. Eukaryota.
ENOG4110SME. LUCA.
HOVERGENiHBG006768.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR031867. MiT/TFE_N.
IPR030532. MITF.
[Graphical view]
PANTHERiPTHR12565:SF91. PTHR12565:SF91. 2 hits.
PfamiPF00010. HLH. 1 hit.
PF15951. MITF_TFEB_C_3_N. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8C6Y4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEALRFEMLI PCSFESLCLS SAEHSGASKP PLSSSTMTSR ILLRQQLMRE
60 70 80 90 100
QMQEQERREQ QQKLQAAQFM QQRVAVSQTP AINVSVPTTL PSATQVPMEV
110 120 130 140 150
LKVQTHLENP TKYHIQQAQR HQVKQYLSTT LANKHASQVL SSPCPNQPGD
160 170 180 190 200
HAMPPVPGSS APNSPMAMLT LNSNCEKEAF YKFEEQSRAE SECPGMNTHS
210 220 230 240 250
RASCMQMDDV IDDIISLESS YNEEILGLMD PALQMANTLP VSGNLIDLYS
260 270 280 290 300
NQGLPPPGLT ISNSCPANLP NIKRELTACI FPTESEARAL AKERQKKDNH
310 320 330 340 350
NLIERRRRFN INDRIKELGT LIPKSNDPDM RWNKGTILKA SVDYIRKLQR
360
EQQRAKDLEN R
Length:361
Mass (Da):40,665
Last modified:March 1, 2003 - v1
Checksum:i1A0B0E07263572C8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei361 – 3611Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052895 mRNA. Translation: BAC35192.1.
RefSeqiNP_001171520.1. NM_001178049.1.
UniGeneiMm.333284.
Mm.454504.

Genome annotation databases

GeneIDi17342.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052895 mRNA. Translation: BAC35192.1.
RefSeqiNP_001171520.1. NM_001178049.1.
UniGeneiMm.333284.
Mm.454504.

3D structure databases

ProteinModelPortaliQ8C6Y4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000044938.

Proteomic databases

PaxDbiQ8C6Y4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi17342.

Organism-specific databases

CTDi4286.
MGIiMGI:104554. Mitf.

Phylogenomic databases

eggNOGiKOG1318. Eukaryota.
ENOG4110SME. LUCA.
HOVERGENiHBG006768.

Miscellaneous databases

ChiTaRSiMitf. mouse.
NextBioi291916.
SOURCEiSearch...

Gene expression databases

BgeeiQ8C6Y4.
GenevisibleiQ8C6Y4. MM.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR031867. MiT/TFE_N.
IPR030532. MITF.
[Graphical view]
PANTHERiPTHR12565:SF91. PTHR12565:SF91. 2 hits.
PfamiPF00010. HLH. 1 hit.
PF15951. MITF_TFEB_C_3_N. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.

Entry informationi

Entry nameiQ8C6Y4_MOUSE
AccessioniPrimary (citable) accession number: Q8C6Y4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 16, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.