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Protein

Galectin

Gene

Lgals8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

LectinUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
GalectinUniRule annotation
Gene namesi
Name:Lgals8Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:1928481. Lgals8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000057554.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097408.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 58GalectinInterPro annotationAdd BLAST58
Domaini93 – 223GalectinInterPro annotationAdd BLAST131

Sequence similaritiesi

Contains 2 galectin domains.UniRule annotation

Phylogenomic databases

eggNOGiKOG3587. Eukaryota.
ENOG4111EA0. LUCA.
GeneTreeiENSGT00760000119105.
HOGENOMiHOG000290194.
HOVERGENiHBG002412.

Family and domain databases

Gene3Di2.60.120.200. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR030638. Galectin_8.
IPR001079. Galectin_CRD.
[Graphical view]
PANTHERiPTHR11346:SF22. PTHR11346:SF22. 1 hit.
PfamiPF00337. Gal-bind_lectin. 2 hits.
[Graphical view]
SMARTiSM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS51304. GALECTIN. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8C6H0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFRKEKSFE IVFMVLKNKF QVAVNGRHVL LYAHRISPEQ IDTVGIYGKV
60 70 80 90 100
NIHSIGFRFS SDLQSMETSA LGLTQINREN IQKPGKLQLS LPFEARLNAS
110 120 130 140 150
MGPGRTVVIK GEVNTNARSF NVDLVAGKTR DIALHLNPRL NVKAFVRNSF
160 170 180 190 200
LQDAWGEEER NITCFPFSSG MYFEMIIYCD VREFKVAING VHSLEYKHRF
210 220
KDLSSIDTLS VDGDIRLLDV RSW
Length:223
Mass (Da):25,428
Last modified:March 1, 2003 - v1
Checksum:i821C9F280AAD90DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154221 Genomic DNA. No translation available.
AK075736 mRNA. Translation: BAC35918.1.
RefSeqiNP_001277984.1. NM_001291055.1.
NP_001277986.1. NM_001291057.1.
NP_001277989.1. NM_001291060.1.
XP_011242627.1. XM_011244325.1.
XP_017171038.1. XM_017315549.1.
UniGeneiMm.474138.
Mm.486765.

Genome annotation databases

EnsembliENSMUST00000135166; ENSMUSP00000120210; ENSMUSG00000057554.
ENSMUST00000143693; ENSMUSP00000118925; ENSMUSG00000057554.
GeneIDi56048.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154221 Genomic DNA. No translation available.
AK075736 mRNA. Translation: BAC35918.1.
RefSeqiNP_001277984.1. NM_001291055.1.
NP_001277986.1. NM_001291057.1.
NP_001277989.1. NM_001291060.1.
XP_011242627.1. XM_011244325.1.
XP_017171038.1. XM_017315549.1.
UniGeneiMm.474138.
Mm.486765.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097408.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000135166; ENSMUSP00000120210; ENSMUSG00000057554.
ENSMUST00000143693; ENSMUSP00000118925; ENSMUSG00000057554.
GeneIDi56048.

Organism-specific databases

CTDi3964.
MGIiMGI:1928481. Lgals8.

Phylogenomic databases

eggNOGiKOG3587. Eukaryota.
ENOG4111EA0. LUCA.
GeneTreeiENSGT00760000119105.
HOGENOMiHOG000290194.
HOVERGENiHBG002412.

Miscellaneous databases

ChiTaRSiLgals8. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000057554.

Family and domain databases

Gene3Di2.60.120.200. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR030638. Galectin_8.
IPR001079. Galectin_CRD.
[Graphical view]
PANTHERiPTHR11346:SF22. PTHR11346:SF22. 1 hit.
PfamiPF00337. Gal-bind_lectin. 2 hits.
[Graphical view]
SMARTiSM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS51304. GALECTIN. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8C6H0_MOUSE
AccessioniPrimary (citable) accession number: Q8C6H0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 5, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.