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Q8C6H0

- Q8C6H0_MOUSE

UniProt

Q8C6H0 - Q8C6H0_MOUSE

Protein

Galectin

Gene

Lgals8

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. carbohydrate binding Source: MGI

    GO - Biological processi

    1. plasma cell differentiation Source: MGI
    2. T cell costimulation Source: MGI

    Keywords - Ligandi

    LectinUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GalectinUniRule annotation
    Gene namesi
    Name:Lgals8Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:1928481. Lgals8.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8C6H0.

    Family & Domainsi

    Sequence similaritiesi

    Contains 2 galectin domains.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117534.
    HOGENOMiHOG000290194.
    HOVERGENiHBG002412.
    InParanoidiQ8C6H0.

    Family and domain databases

    Gene3Di2.60.120.200. 2 hits.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR001079. Galectin_CRD.
    [Graphical view]
    PfamiPF00337. Gal-bind_lectin. 2 hits.
    [Graphical view]
    SMARTiSM00908. Gal-bind_lectin. 1 hit.
    SM00276. GLECT. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 2 hits.
    PROSITEiPS51304. GALECTIN. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8C6H0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPFRKEKSFE IVFMVLKNKF QVAVNGRHVL LYAHRISPEQ IDTVGIYGKV    50
    NIHSIGFRFS SDLQSMETSA LGLTQINREN IQKPGKLQLS LPFEARLNAS 100
    MGPGRTVVIK GEVNTNARSF NVDLVAGKTR DIALHLNPRL NVKAFVRNSF 150
    LQDAWGEEER NITCFPFSSG MYFEMIIYCD VREFKVAING VHSLEYKHRF 200
    KDLSSIDTLS VDGDIRLLDV RSW 223
    Length:223
    Mass (Da):25,428
    Last modified:March 1, 2003 - v1
    Checksum:i821C9F280AAD90DD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154221 Genomic DNA. No translation available.
    AK075736 mRNA. Translation: BAC35918.1.
    RefSeqiNP_001277984.1. NM_001291055.1.
    NP_001277986.1. NM_001291057.1.
    NP_001277989.1. NM_001291060.1.
    UniGeneiMm.474138.
    Mm.486765.

    Genome annotation databases

    EnsembliENSMUST00000135166; ENSMUSP00000120210; ENSMUSG00000057554.
    ENSMUST00000143693; ENSMUSP00000118925; ENSMUSG00000057554.
    GeneIDi56048.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154221 Genomic DNA. No translation available.
    AK075736 mRNA. Translation: BAC35918.1 .
    RefSeqi NP_001277984.1. NM_001291055.1.
    NP_001277986.1. NM_001291057.1.
    NP_001277989.1. NM_001291060.1.
    UniGenei Mm.474138.
    Mm.486765.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000135166 ; ENSMUSP00000120210 ; ENSMUSG00000057554 .
    ENSMUST00000143693 ; ENSMUSP00000118925 ; ENSMUSG00000057554 .
    GeneIDi 56048.

    Organism-specific databases

    MGIi MGI:1928481. Lgals8.

    Phylogenomic databases

    GeneTreei ENSGT00750000117534.
    HOGENOMi HOG000290194.
    HOVERGENi HBG002412.
    InParanoidi Q8C6H0.

    Miscellaneous databases

    ChiTaRSi LGALS8. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8C6H0.

    Family and domain databases

    Gene3Di 2.60.120.200. 2 hits.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR001079. Galectin_CRD.
    [Graphical view ]
    Pfami PF00337. Gal-bind_lectin. 2 hits.
    [Graphical view ]
    SMARTi SM00908. Gal-bind_lectin. 1 hit.
    SM00276. GLECT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 2 hits.
    PROSITEi PS51304. GALECTIN. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    10. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8C6H0_MOUSE
    AccessioniPrimary (citable) accession number: Q8C6H0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3