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Q8C6H0

- Q8C6H0_MOUSE

UniProt

Q8C6H0 - Q8C6H0_MOUSE

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Protein

Galectin

Gene

Lgals8

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. carbohydrate binding Source: MGI

GO - Biological processi

  1. plasma cell differentiation Source: MGI
  2. T cell costimulation Source: MGI
Complete GO annotation...

Keywords - Ligandi

LectinUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
GalectinUniRule annotation
Gene namesi
Name:Lgals8Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:1928481. Lgals8.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8C6H0.

Family & Domainsi

Sequence similaritiesi

Contains 2 galectin domains.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119105.
HOGENOMiHOG000290194.
HOVERGENiHBG002412.

Family and domain databases

Gene3Di2.60.120.200. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR001079. Galectin_CRD.
[Graphical view]
PfamiPF00337. Gal-bind_lectin. 2 hits.
[Graphical view]
SMARTiSM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS51304. GALECTIN. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8C6H0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPFRKEKSFE IVFMVLKNKF QVAVNGRHVL LYAHRISPEQ IDTVGIYGKV
60 70 80 90 100
NIHSIGFRFS SDLQSMETSA LGLTQINREN IQKPGKLQLS LPFEARLNAS
110 120 130 140 150
MGPGRTVVIK GEVNTNARSF NVDLVAGKTR DIALHLNPRL NVKAFVRNSF
160 170 180 190 200
LQDAWGEEER NITCFPFSSG MYFEMIIYCD VREFKVAING VHSLEYKHRF
210 220
KDLSSIDTLS VDGDIRLLDV RSW
Length:223
Mass (Da):25,428
Last modified:March 1, 2003 - v1
Checksum:i821C9F280AAD90DD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154221 Genomic DNA. No translation available.
AK075736 mRNA. Translation: BAC35918.1.
RefSeqiNP_001277984.1. NM_001291055.1.
NP_001277986.1. NM_001291057.1.
NP_001277989.1. NM_001291060.1.
UniGeneiMm.474138.
Mm.486765.

Genome annotation databases

EnsembliENSMUST00000135166; ENSMUSP00000120210; ENSMUSG00000057554.
ENSMUST00000143693; ENSMUSP00000118925; ENSMUSG00000057554.
GeneIDi56048.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154221 Genomic DNA. No translation available.
AK075736 mRNA. Translation: BAC35918.1 .
RefSeqi NP_001277984.1. NM_001291055.1.
NP_001277986.1. NM_001291057.1.
NP_001277989.1. NM_001291060.1.
UniGenei Mm.474138.
Mm.486765.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000135166 ; ENSMUSP00000120210 ; ENSMUSG00000057554 .
ENSMUST00000143693 ; ENSMUSP00000118925 ; ENSMUSG00000057554 .
GeneIDi 56048.

Organism-specific databases

CTDi 3964.
MGIi MGI:1928481. Lgals8.

Phylogenomic databases

GeneTreei ENSGT00760000119105.
HOGENOMi HOG000290194.
HOVERGENi HBG002412.

Miscellaneous databases

ChiTaRSi LGALS8. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8C6H0.

Family and domain databases

Gene3Di 2.60.120.200. 2 hits.
InterProi IPR013320. ConA-like_dom.
IPR001079. Galectin_CRD.
[Graphical view ]
Pfami PF00337. Gal-bind_lectin. 2 hits.
[Graphical view ]
SMARTi SM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 2 hits.
PROSITEi PS51304. GALECTIN. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CerebellumImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8C6H0_MOUSE
AccessioniPrimary (citable) accession number: Q8C6H0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3