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Protein

Transmembrane protein 145

Gene

Tmem145

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 145
Gene namesi
Name:Tmem145
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:3607779. Tmem145.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Transmembranei189 – 209HelicalSequence analysisAdd BLAST21
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21
Transmembranei255 – 275HelicalSequence analysisAdd BLAST21
Transmembranei296 – 316HelicalSequence analysisAdd BLAST21
Transmembranei332 – 352HelicalSequence analysisAdd BLAST21
Transmembranei363 – 383HelicalSequence analysisAdd BLAST21
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002803561 – 746Transmembrane protein 145Add BLAST746

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi35N-linked (GlcNAc...)Sequence analysis1
Glycosylationi250N-linked (GlcNAc...)Sequence analysis1
Glycosylationi458N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8C4U2.
PRIDEiQ8C4U2.

PTM databases

iPTMnetiQ8C4U2.
PhosphoSitePlusiQ8C4U2.

Expressioni

Gene expression databases

CleanExiMM_TMEM145.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104046.

Structurei

3D structure databases

ProteinModelPortaliQ8C4U2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4290. Eukaryota.
ENOG410XRGS. LUCA.
HOGENOMiHOG000074087.
HOVERGENiHBG094058.
InParanoidiQ8C4U2.
PhylomeDBiQ8C4U2.

Family and domain databases

InterProiIPR019336. Intimal_thickness-rel_rcpt.
[Graphical view]
PfamiPF10192. GpcrRhopsn4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8C4U2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPSRAPVLG RLLPPLLLLL LPLYPRTRAK YVRGNLSSKE DWVFLTRFCF
60 70 80 90 100
LSDYGRLDFR FRYPEAKCCQ NILLYFDDPS QWPAVYKARD KDCLAKESVI
110 120 130 140 150
RPENNQVINL TTQYAWSGCQ VVSEEGTRYL SCSSGRSFRS VRERWWYIAL
160 170 180 190 200
SKCGGDGLQL EYEMVLTNGK SFWTRHFSAD EFGILETDVT FLLIFTLIFV
210 220 230 240 250
LSCYFGYLLK GRQLLHTTYK MFMAAAGVEV LSLLFFCIYW GQYATDGIGN
260 270 280 290 300
GSVKILAKLL FSSSFLIFLL TLILLGKGFT VTRGRISHSG SVKLSVYMTL
310 320 330 340 350
YTLTHVVLLI YEAEFFDPGQ VLYTYESPAG YGLIGLQVAA YVWFCYAVLV
360 370 380 390 400
SLRHYPEKQP FYVPFFAAYT LWFFAVPVMA LIANFGIPKW AREKIVNGIQ
410 420 430 440 450
LGIHLYAHGV FLIMTRPSAA NKNFPYHVRT SQIASAGVPG PGGSQSADKA
460 470 480 490 500
FPQHVYGNVT FISDSVPNFT ELFSIPPPTS SAGKQVEETA VAAAVAPRGR
510 520 530 540 550
VVTMAEPGAA SPPPPARFSK AVHSGWDGPT PSYQPLVPPE QRRGKPASPN
560 570 580 590 600
TSACTQPGAL HPRSEHPFPA SAPRAAHRAP AGLRNPVSLP AQGLGHARHP
610 620 630 640 650
APLPHPAPTL DALRPAPFPL VPNGPAGAVL RVPSLSPCPE WLRNLDSRCS
660 670 680 690 700
VISAPLTPFE TSDPAGLRNT RDDRLDPARP SRTLRPSSHC LETDIVKLVS
710 720 730 740
TLKPSLGFVT SDLCFVRPSE CQGPSHGLWQ KDVFSSCQNK EDSLSF
Length:746
Mass (Da):82,473
Last modified:March 1, 2003 - v1
Checksum:iE4BF8600F35CF733
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK081054 mRNA. Translation: BAC38124.1.
RefSeqiNP_899134.2. NM_183311.2.
UniGeneiMm.260740.

Genome annotation databases

GeneIDi330485.
KEGGimmu:330485.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK081054 mRNA. Translation: BAC38124.1.
RefSeqiNP_899134.2. NM_183311.2.
UniGeneiMm.260740.

3D structure databases

ProteinModelPortaliQ8C4U2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104046.

PTM databases

iPTMnetiQ8C4U2.
PhosphoSitePlusiQ8C4U2.

Proteomic databases

PaxDbiQ8C4U2.
PRIDEiQ8C4U2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi330485.
KEGGimmu:330485.

Organism-specific databases

CTDi284339.
MGIiMGI:3607779. Tmem145.

Phylogenomic databases

eggNOGiKOG4290. Eukaryota.
ENOG410XRGS. LUCA.
HOGENOMiHOG000074087.
HOVERGENiHBG094058.
InParanoidiQ8C4U2.
PhylomeDBiQ8C4U2.

Miscellaneous databases

ChiTaRSiTmem145. mouse.
PROiQ8C4U2.
SOURCEiSearch...

Gene expression databases

CleanExiMM_TMEM145.

Family and domain databases

InterProiIPR019336. Intimal_thickness-rel_rcpt.
[Graphical view]
PfamiPF10192. GpcrRhopsn4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTM145_MOUSE
AccessioniPrimary (citable) accession number: Q8C4U2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.