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Protein
Submitted name:

Uncharacterized protein

Gene

Itsn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Itsn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1338069. Itsn1.

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiQ8C4B5.
PeptideAtlasiQ8C4B5.
PRIDEiQ8C4B5.

Expressioni

Gene expression databases

GenevisibleiQ8C4B5. MM.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ8C4B5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 94SH3InterPro annotationAdd BLAST59
Domaini108 – 172SH3InterPro annotationAdd BLAST65
Domaini189 – 248SH3InterPro annotationAdd BLAST60
Domaini271 – 457DHInterPro annotationAdd BLAST187
Domaini496 – 605PHInterPro annotationAdd BLAST110
Domaini631 – 713C2InterPro annotationAdd BLAST83

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1029. Eukaryota.
KOG4305. Eukaryota.
COG5422. LUCA.
HOGENOMiHOG000010175.
HOVERGENiHBG100981.
KOiK20045.

Family and domain databases

CDDicd00160. RhoGEF. 1 hit.
Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.150. 1 hit.
InterProiView protein in InterPro
IPR000008. C2_dom.
IPR035892. C2_domain_sf.
IPR035899. DBL_dom_sf.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH-like_dom_sf.
IPR001849. PH_domain.
IPR036028. SH3-like_dom_sf.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00168. C2. 1 hit.
PF16652. PH_13. 1 hit.
PF00621. RhoGEF. 1 hit.
PF14604. SH3_9. 3 hits.
PRINTSiPR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00239. C2. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 3 hits.
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF50044. SSF50044. 3 hits.
SSF50729. SSF50729. 1 hit.
PROSITEiView protein in PROSITE
PS50004. C2. 1 hit.
PS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 3 hits.

Sequencei

Sequence statusi: Fragment.

Q8C4B5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PHFRGPVRKS TSIDTGPTES PASLKRVASP AAKPAIPGEE FIAMYTYESS
60 70 80 90 100
EQGDLTFQQG DVIVVTKKDG DWWTGTGGDK SGVFPSNYVR LKDSEGSGTA
110 120 130 140 150
GKTGSLGKKP EIAQVIASYA ATGPEQLTLA PGQLILIRKK NPGGWWEGEL
160 170 180 190 200
QARGKKRQIG WFPANYVKLL SPGTSKITPT ELPKTAVQPA VCQVIGMYDY
210 220 230 240 250
TAQNDDELAF SKGQIINVLN KEDPDWWKGE VSGQVGLFPS NYVKLTTDMD
260 270 280 290 300
PSQQWCSDLH LLDMLTPTER KRQGYIHELI VTEENYVNDL QLVTEIFQKP
310 320 330 340 350
LTESELLTEK EVAMIFVNWK ELIMCNIKLL KALRVRKKMS GEKMPVKMIG
360 370 380 390 400
DILSAQLPHM QPYIRFCSCQ LNGAALIQQK TDEAPDFKEF VKRLAMDPRC
410 420 430 440 450
KGMPLSSFIL KPMQRVTRYP LIIKNILENT PENHPDHSHL KHALEKAEEL
460 470 480 490 500
CSQVNEGVRE KENSDRLEWI QAHVQCEGLS EQLVFNSVTN CLGPRKFLHS
510 520 530 540 550
GKLYKAKSNK ELYGFLFNDF LLLTQITKPL GSSGTDKVFS PKSNLQYKMY
560 570 580 590 600
KTPIFLNEVL VKLPTDPSGD EPIFHISHID RVYTLRAESI NERTAWVQKI
610 620 630 640 650
KAASELYIET EKKKREKAYL VRSQRATGIG RLMVNVVEGI ELKPCRSHGK
660 670 680 690 700
SNPYCEVTMG SQCHITKTIQ DTLNPKWNSN CQFFIRDLEQ EVLCITVFER
710 720 730 740 750
DQLSADDFLG RTEIRVADIK KDQGSKGPVT KCLLLHEVPT GEIVVRLDLQ

LFDEP
Length:755
Mass (Da):85,108
Last modified:March 1, 2003 - v1
Checksum:i8FD0026865297597
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK082606 mRNA. Translation: BAC38546.1.
RefSeqiNP_034717.2. NM_010587.2.
UniGeneiMm.40546.

Genome annotation databases

GeneIDi16443.
KEGGimmu:16443.

Similar proteinsi

Entry informationi

Entry nameiQ8C4B5_MOUSE
AccessioniPrimary (citable) accession number: Q8C4B5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 22, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)