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Protein
Submitted name:

Putative uncharacterized protein

Gene

Itsn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Itsn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1338069. Itsn1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ8C4B5.
PeptideAtlasiQ8C4B5.

Expressioni

Gene expression databases

GenevisibleiQ8C4B5. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109635.

Structurei

3D structure databases

ProteinModelPortaliQ8C4B5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 9459SH3InterPro annotationAdd
BLAST
Domaini108 – 17265SH3InterPro annotationAdd
BLAST
Domaini189 – 24860SH3InterPro annotationAdd
BLAST
Domaini271 – 457187DH (DBL-homology)InterPro annotationAdd
BLAST
Domaini496 – 605110PHInterPro annotationAdd
BLAST
Domaini631 – 71383C2InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 C2 domain.UniRule annotation
Contains DH (DBL-homology) domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG1029. Eukaryota.
KOG4305. Eukaryota.
COG5422. LUCA.
HOGENOMiHOG000010175.
HOVERGENiHBG100981.
KOiK20045.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.150. 1 hit.
InterProiIPR000008. C2_dom.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00168. C2. 1 hit.
PF16652. PH_13. 1 hit.
PF00621. RhoGEF. 1 hit.
PF14604. SH3_9. 3 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00239. C2. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 3 hits.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF50044. SSF50044. 3 hits.
SSF50729. SSF50729. 1 hit.
PROSITEiPS50004. C2. 1 hit.
PS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8C4B5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PHFRGPVRKS TSIDTGPTES PASLKRVASP AAKPAIPGEE FIAMYTYESS
60 70 80 90 100
EQGDLTFQQG DVIVVTKKDG DWWTGTGGDK SGVFPSNYVR LKDSEGSGTA
110 120 130 140 150
GKTGSLGKKP EIAQVIASYA ATGPEQLTLA PGQLILIRKK NPGGWWEGEL
160 170 180 190 200
QARGKKRQIG WFPANYVKLL SPGTSKITPT ELPKTAVQPA VCQVIGMYDY
210 220 230 240 250
TAQNDDELAF SKGQIINVLN KEDPDWWKGE VSGQVGLFPS NYVKLTTDMD
260 270 280 290 300
PSQQWCSDLH LLDMLTPTER KRQGYIHELI VTEENYVNDL QLVTEIFQKP
310 320 330 340 350
LTESELLTEK EVAMIFVNWK ELIMCNIKLL KALRVRKKMS GEKMPVKMIG
360 370 380 390 400
DILSAQLPHM QPYIRFCSCQ LNGAALIQQK TDEAPDFKEF VKRLAMDPRC
410 420 430 440 450
KGMPLSSFIL KPMQRVTRYP LIIKNILENT PENHPDHSHL KHALEKAEEL
460 470 480 490 500
CSQVNEGVRE KENSDRLEWI QAHVQCEGLS EQLVFNSVTN CLGPRKFLHS
510 520 530 540 550
GKLYKAKSNK ELYGFLFNDF LLLTQITKPL GSSGTDKVFS PKSNLQYKMY
560 570 580 590 600
KTPIFLNEVL VKLPTDPSGD EPIFHISHID RVYTLRAESI NERTAWVQKI
610 620 630 640 650
KAASELYIET EKKKREKAYL VRSQRATGIG RLMVNVVEGI ELKPCRSHGK
660 670 680 690 700
SNPYCEVTMG SQCHITKTIQ DTLNPKWNSN CQFFIRDLEQ EVLCITVFER
710 720 730 740 750
DQLSADDFLG RTEIRVADIK KDQGSKGPVT KCLLLHEVPT GEIVVRLDLQ

LFDEP
Length:755
Mass (Da):85,108
Last modified:March 1, 2003 - v1
Checksum:i8FD0026865297597
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK082606 mRNA. Translation: BAC38546.1.
RefSeqiNP_034717.2. NM_010587.2.
UniGeneiMm.40546.

Genome annotation databases

GeneIDi16443.
KEGGimmu:16443.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK082606 mRNA. Translation: BAC38546.1.
RefSeqiNP_034717.2. NM_010587.2.
UniGeneiMm.40546.

3D structure databases

ProteinModelPortaliQ8C4B5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109635.

Proteomic databases

PaxDbiQ8C4B5.
PeptideAtlasiQ8C4B5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi16443.
KEGGimmu:16443.

Organism-specific databases

CTDi6453.
MGIiMGI:1338069. Itsn1.

Phylogenomic databases

eggNOGiKOG1029. Eukaryota.
KOG4305. Eukaryota.
COG5422. LUCA.
HOGENOMiHOG000010175.
HOVERGENiHBG100981.
KOiK20045.

Miscellaneous databases

ChiTaRSiItsn1. mouse.
SOURCEiSearch...

Gene expression databases

GenevisibleiQ8C4B5. MM.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.150. 1 hit.
InterProiIPR000008. C2_dom.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00168. C2. 1 hit.
PF16652. PH_13. 1 hit.
PF00621. RhoGEF. 1 hit.
PF14604. SH3_9. 3 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00239. C2. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 3 hits.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF50044. SSF50044. 3 hits.
SSF50729. SSF50729. 1 hit.
PROSITEiPS50004. C2. 1 hit.
PS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8C4B5_MOUSE
AccessioniPrimary (citable) accession number: Q8C4B5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.