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Unreviewed, UniProtKB/TrEMBL Q8C443 (Q8C443_MOUSE)

Last modified February 9, 2010. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Nuclear factor of activated T-cells c2 isoform IA-IIS-VIIa EMBL ACG55621.1
Submitted name:
    Nuclear factor of activated T-cells c2 isoform IB-IIS-VIIa EMBL ACG55622.1
    Putative uncharacterized protein EMBL BAC38768.1
Gene names
Name: Nfatc2 MGI 102463
OrganismMus musculus (Mouse) EMBL BAC38768.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length452 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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Ontologies

Gene Ontology (GO)
   Biological processregulation of transcription, DNA-dependent

Inferred from electronic annotation. Source: InterPro

   Cellular componentnucleus

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functiontranscription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequences

Sequence LengthMass (Da)Tools
Q8C443-1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 108540A5212CD5F7

FASTA45248,908
        10         20         30         40         50         60 
MSPRTSLAED SCLGRHSPVP RPASRSSSPG AKRRHSCAEA LVAPLPAASP QRSRSPSPQP 

        70         80         90        100        110        120 
SPHVALQDDS IPAGYPPTAG SAVLMDALNT LATDSPCGIP SKIWKTSPDP TPVSTAPSKA 

       130        140        150        160        170        180 
GLARHIYPTV EFLGPCEQEE RRNSAPESIL LVPPTWPKQL VPAIPICSIP VTASLPPLEW 

       190        200        210        220        230        240 
PLSNQSGSYE LRIEVQPKPH HRAHYETEGS RGAVKAPTGG HPVVQLHGYM ENKPLGLQIF 

       250        260        270        280        290        300 
IGTADERILK PHAFYQVHRI TGKTVTTTSY EKIVGNTKVL EIPLEPKNNM RATIDCAGIL 

       310        320        330        340        350        360 
KLRNADIELR KGETDIGRKN TRVRLVFRVH VPEPSGRIVS LQAASNPIEC SQRSAHELPM 

       370        380        390        400        410        420 
VERQDMDSCL VYGGQQMILT GQNFTAESKV VFMEKTTGPA GTCETRPLPI SLISADRLSP 

       430        440        450 
WLSRLQRNPP GSVFRCSVLL PAPGSSLVLL AL

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References

« Hide 'large scale' references
[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J EMBL BAC38768.1.
Tissue: Hippocampus EMBL BAC38768.1.
[2]"Alternative splicing and expression of human and mouse NFAT genes."
Vihma H., Pruunsild P., Timmusk T.
Genomics 0:0-0(2008)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6 EMBL ACG55621.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		EU887601 mRNA. Translation: ACG55621.1.
EU887602 mRNA. Translation: ACG55622.1.
AK083119 mRNA. Translation: BAC38768.1.
IPIIPI00875212.
RefSeqNP_001032254.1.
NP_001032255.1.
UniGeneMm.116802

3D structure databases

HSSPHSSP built from PDB template 1PZU based on UniProtKB Q13469.
SMRQ8C443. Positions 173-397.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8C443.

Proteomic databases

PRIDEQ8C443.

Genome annotation databases

EnsemblENSMUST00000029057; ENSMUSP00000029057; ENSMUSG00000027544; Mus musculus. [Genome view]
ENSMUST00000099067; ENSMUSP00000096666; ENSMUSG00000027544; Mus musculus. [Genome view]
ENSMUST00000109182; ENSMUSP00000104810; ENSMUSG00000027544; Mus musculus. [Genome view]
GeneID18019.
KEGGmmu:18019.
UCSCuc008oax.1. mouse.

Organism-specific databases

CTD18019.
MGIMGI:102463. Nfatc2.

Phylogenomic databases

HOVERGENQ8C443.

Gene expression databases

ArrayExpressQ8C443.
BgeeQ8C443.
GenevestigatorQ8C443.

Family and domain databases

InterProIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR008366. NFAT.
IPR018286. NFAT_sbgrp.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view]
Gene3DG3DSA:2.60.40.10. Ig-like_fold. 1 hit.
G3DSA:2.60.40.340. RHD. 1 hit.
PANTHERPTHR12533. NFAT. 1 hit.
PfamPF00554. RHD. 1 hit.
[Graphical view]
PRINTSPR01789. NUCFACTORATC.
PROSITEPS50254. REL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio293063.
SOURCESearch...

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Entry information

Entry nameQ8C443_MOUSE
AccessionPrimary (citable) accession number: Q8C443
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: February 9, 2010
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information