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Protein
Submitted name:

Lymphoid enhancer binding factor 1, isoform CRA_b

Gene

Lef1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi231 – 299HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Lymphoid enhancer binding factor 1, isoform CRA_bImported
Submitted name:
Lymphoid enhancer-binding factor 1Imported
Gene namesi
Name:Lef1Imported
ORF Names:mCG_10208Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:96770. Lef1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000027985.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini231 – 299HMG boxInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG3248. Eukaryota.
ENOG41109RU. LUCA.
GeneTreeiENSGT00390000009964.
HOVERGENiHBG000419.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiView protein in InterPro
IPR013558. CTNNB1-bd_N.
IPR009071. HMG_box_dom.
IPR036910. HMG_box_dom_sf.
IPR028769. LEF1.
IPR024940. TCF/LEF.
PANTHERiPTHR10373. PTHR10373. 1 hit.
PTHR10373:SF11. PTHR10373:SF11. 1 hit.
PfamiView protein in Pfam
PF08347. CTNNB1_binding. 1 hit.
PF00505. HMG_box. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 1 hit.
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8C402-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVVRQAPS SQEPYHDKAR EHPDEGKHPD GGLYNKGPSY SSYSGYIMMP
60 70 80 90 100
NMNSDPYMSN GSLSPPIPRT SNKVPVVQPS HAVHPLTPLI TYSDEHFSPG
110 120 130 140 150
SHPSHIPSDV NSKQGMSRHP PAPEIPTFYP LSPGGVGQIT PPIGWQGQPV
160 170 180 190 200
YPITGGFRQP YPSSLSGDTS MSRFSHHMIP GPPGPHTTGI PHPAIVTPQV
210 220 230 240 250
KQEHPHTDSD LMHVKPQHEQ RKEQEPKRPH IKKPLNAFML YMKEMRANVV
260 270 280 290 300
AECTLKESAA INQILGRRWH ALSREEQAKY YELARKERQL HMQLYPGWSA
310 320 330
RDNYGKKKKR KREKLQESTS GTGPRMTAAY I
Length:331
Mass (Da):37,041
Last modified:March 1, 2003 - v1
Checksum:i383E0F6AA6F7E84F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114668 Genomic DNA. No translation available.
AC123634 Genomic DNA. No translation available.
AK083328 mRNA. Translation: BAC38867.1.
CH466532 Genomic DNA. Translation: EDL12205.1.
RefSeqiNP_001263332.1. NM_001276403.1.
UniGeneiMm.255219.

Genome annotation databases

EnsembliENSMUST00000098611; ENSMUSP00000096211; ENSMUSG00000027985.
GeneIDi16842.
UCSCiuc008rjk.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8C402_MOUSE
AccessioniPrimary (citable) accession number: Q8C402
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported