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Q8C3X2 (CC90B_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Coiled-coil domain-containing protein 90B, mitochondrial
Gene names
Name:Ccdc90b
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Mitochondrion By similarity. Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the CCDC90 family.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q8C3X2-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q8C3X2-2)

The sequence of this isoform differs from the canonical sequence as follows:
     109-142: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 4242Mitochondrion Potential
Chain43 – 256214Coiled-coil domain-containing protein 90B, mitochondrial
PRO_0000295696

Regions

Transmembrane231 – 25323Helical; Potential
Coiled coil129 – 16739 Potential

Natural variations

Alternative sequence109 – 14234Missing in isoform 2.
VSP_027004

Experimental info

Sequence conflict151G → C in BAB26248. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 0F5BB3CBDA61994B

FASTA25629,597
        10         20         30         40         50         60 
MRSRWIWRFL RPDGGGIRWT STPHGRLSPA LRRGFLTTTT KSDYDRRPVD ITPLEQRKLT 

        70         80         90        100        110        120 
FDTHALVQDL ETHGFDKTQA QTIVSVLSTL SNVSLDTIYK EMVTKAQQEI TVQQLMAHLD 

       130        140        150        160        170        180 
SIRKDMVILE KSEFANLRAE NEKMKIELDQ VKQQLTNETS RIRADNKLDI NLERSRVTDM 

       190        200        210        220        230        240 
FTDQEKQLIE ATNEFAKKDT QTKSIISETS NKIDTEIASL KTLMESSKLE TIRYLAASVF 

       250 
TCLAIALGFY RFWKEN 

« Hide

Isoform 2 [UniParc].

Checksum: 682028974E38370F
Show »

FASTA22225,642

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: C57BL/6J.
Tissue: Heart and Tongue.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Tissue: Mammary gland.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK084673 mRNA. Translation: BAC39246.1.
AK009370 mRNA. Translation: BAB26248.1.
BC034878 mRNA. Translation: AAH34878.1.
BC115973 mRNA. Translation: AAI15974.1.
CCDSCCDS21449.1. [Q8C3X2-1]
CCDS52309.1. [Q8C3X2-2]
RefSeqNP_001156390.1. NM_001162918.1. [Q8C3X2-2]
NP_079791.2. NM_025515.3. [Q8C3X2-1]
UniGeneMm.21173.

3D structure databases

ProteinModelPortalQ8C3X2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ8C3X2. 2 interactions.
MINTMINT-4114288.
STRING10090.ENSMUSP00000032842.

PTM databases

PhosphoSiteQ8C3X2.

Proteomic databases

MaxQBQ8C3X2.
PaxDbQ8C3X2.
PRIDEQ8C3X2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000032842; ENSMUSP00000032842; ENSMUSG00000030613. [Q8C3X2-1]
ENSMUST00000085017; ENSMUSP00000082090; ENSMUSG00000030613. [Q8C3X2-2]
GeneID66365.
KEGGmmu:66365.
UCSCuc009ihv.2. mouse. [Q8C3X2-1]
uc009ihw.2. mouse. [Q8C3X2-2]

Organism-specific databases

CTD60492.
MGIMGI:1913615. Ccdc90b.

Phylogenomic databases

eggNOGNOG297085.
GeneTreeENSGT00390000016409.
HOGENOMHOG000294135.
HOVERGENHBG107611.
InParanoidQ8C3X2.
OMATAMAEVI.
OrthoDBEOG7SR4NS.
PhylomeDBQ8C3X2.
TreeFamTF331442.

Gene expression databases

BgeeQ8C3X2.
CleanExMM_CCDC90B.
GenevestigatorQ8C3X2.

Family and domain databases

InterProIPR024461. DUF1640.
[Graphical view]
PfamPF07798. DUF1640. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio321453.
PROQ8C3X2.
SOURCESearch...

Entry information

Entry nameCC90B_MOUSE
AccessionPrimary (citable) accession number: Q8C3X2
Secondary accession number(s): Q8JZY3, Q9D7C1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot