Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Amino acid transporter

Gene

Slc1a3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processSymportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Amino acid transporterUniRule annotation
Gene namesi
Name:Slc1a3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99917. Slc1a3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 68HelicalUniRule annotationAdd BLAST25
Transmembranei88 – 111HelicalUniRule annotationAdd BLAST24
Transmembranei123 – 145HelicalUniRule annotationAdd BLAST23
Transmembranei241 – 260HelicalUniRule annotationAdd BLAST20
Transmembranei281 – 302HelicalUniRule annotationAdd BLAST22
Transmembranei314 – 339HelicalUniRule annotationAdd BLAST26
Transmembranei346 – 365HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8C3T7.
PeptideAtlasiQ8C3T7.
PRIDEiQ8C3T7.

Structurei

3D structure databases

ProteinModelPortaliQ8C3T7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3787. Eukaryota.
COG1301. LUCA.
HOVERGENiHBG000080.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiView protein in InterPro
IPR036458. Na-dicarbo_symporter_sf.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
PfamiView protein in Pfam
PF00375. SDF. 1 hit.
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 2 hits.
PROSITEiView protein in PROSITE
PS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8C3T7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKSNGEEPR MGGRMERLQQ GVRKRTLLAK KKVQSLTKED VKSYLFRNAF
60 70 80 90 100
VLLTVTAVIV GTILGFALRP YKMSYREVKY FSFPGELLMR MLQMLVLPLI
110 120 130 140 150
ISSLVTGMAA LDSKASGKMG MRAVVYYMTT TIIAVVIGII IVIIIHPGKG
160 170 180 190 200
TKENMYREGK IVQVTAADAF LDLIRNMFPP NLVEACFKQF KTSYEKRSFK
210 220 230 240 250
VPIQSNETLL GAVINNVSEA METLTRIREE MVPVPGSVNG VNALGLVVSS
260 270 280 290 300
MCFGFVIGNM KEQGQALREF FDSLNEAIMR LVAVIMWYAP LGILFLIAGK
310 320 330 340 350
IVEMEDMGVI GGQLAMYTVT VIVGLLIHAV IVLPLLYFLV TRKNPWVFIG
360 370 380 390 400
GLLQALITAL GTSSSSATLP ITFKCLEENN GVDKRITRFV LPVGATINMD
410 420 430 440 450
GTALYEALAA IFIAQVNNFD LNFGQIITIS ITATAASIGA AGIPQAGLVT
460 470 480 490 500
MVIVLTSVGL PTDDITLIIA VDWFLDRLRT TTNVLGDSLG AGIVEHLSRH
510 520 530 540
ELKNRDVEMG NSVIEENEMK KPYQLIAQDN EPEKPVADSE TKM
Length:543
Mass (Da):59,562
Last modified:March 1, 2003 - v1
Checksum:i40B6520A1D50BF6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK084968 mRNA. Translation: BAC39324.1.
UniGeneiMm.204834.

Similar proteinsi

Entry informationi

Entry nameiQ8C3T7_MOUSE
AccessioniPrimary (citable) accession number: Q8C3T7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)