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Protein
Submitted name:

Putative uncharacterized protein

Gene

Casp9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei274UniRule annotation1
Active sitei324UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiC14.010.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Casp9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1277950. Casp9.

PTM / Processingi

Proteomic databases

PaxDbiQ8C3Q0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028914.
GenevisibleiQ8C3Q0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030747.

Structurei

3D structure databases

ProteinModelPortaliQ8C3Q0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 91CARDInterPro annotationAdd BLAST91
Domaini196 – 328CASPASE_P20InterPro annotationAdd BLAST133
Domaini368 – 452CASPASE_P10InterPro annotationAdd BLAST85

Sequence similaritiesi

Belongs to the peptidase C14A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
HOVERGENiHBG059022.
OMAiVFEQWAH.

Family and domain databases

CDDicd00032. CASc. 1 hit.
Gene3Di1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProiIPR001315. CARD.
IPR033171. Caspase-9.
IPR029030. Caspase-like_dom.
IPR033139. Caspase_cys_AS.
IPR016129. Caspase_his_AS.
IPR011029. DEATH-like_dom.
IPR002138. Pept_C14_p10.
IPR001309. Pept_C14_p20.
IPR015917. Pept_C14A.
IPR017350. Pept_C14A_CASP1-typ.
[Graphical view]
PANTHERiPTHR10454:SF157. PTHR10454:SF157. 1 hit.
PfamiPF00619. CARD. 1 hit.
[Graphical view]
PIRSFiPIRSF038001. Caspase_ICE. 1 hit.
PRINTSiPR00376. IL1BCENZYME.
SMARTiSM00114. CARD. 1 hit.
SM00115. CASc. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF52129. SSF52129. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS01122. CASPASE_CYS. 1 hit.
PS01121. CASPASE_HIS. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8C3Q0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DEADRQLLRR CRVRLVSELQ VAELWDALLS RELFTRDMIE DIQQAGSGSR
60 70 80 90 100
RDQARQLVTD LETRGRQALP LFISCLEDTG QGTLASLLQS GRQAAKQDPE
110 120 130 140 150
AVKPLDHLVP VVLGPMGLTA KEQRVVKLDP SQPAVGNLTP VVLGPEELWP
160 170 180 190 200
ARLKPEVLRP ETPRPVDIGS GGAHDVCVPG KIRGHADMAY TLDSDPCGHC
210 220 230 240 250
LIINNVNFCP SSGLGTRTGS NLDRDKLEHR FRWLRFMVEV KNDLTAKKMV
260 270 280 290 300
TALMEMAHRN HRALDCFVVV ILSHGCQASH LQFPGAVYGT DGCSVSIEKI
310 320 330 340 350
VNIFNGSGCP SLGGKPKLFF IQACGGEQKD HGFEVACTSS QGRTLDSDSE
360 370 380 390 400
PDAVPYQEGP RPLDQLDAVS SLPTPSDILV SYSTFPGFVS WRDKKSGSWY
410 420 430 440 450
IETLDGILEQ WARSEDLQSL LLRVANAVSA KGTYKQIPGC FNFLRKKLFF

KTS
Length:453
Mass (Da):49,848
Last modified:March 1, 2003 - v1
Checksum:i8F7D1C50F7ABA68F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK085152 mRNA. Translation: BAC39378.1.
UniGeneiMm.88829.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK085152 mRNA. Translation: BAC39378.1.
UniGeneiMm.88829.

3D structure databases

ProteinModelPortaliQ8C3Q0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030747.

Protein family/group databases

MEROPSiC14.010.

Proteomic databases

PaxDbiQ8C3Q0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1277950. Casp9.

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
HOVERGENiHBG059022.
OMAiVFEQWAH.

Miscellaneous databases

ChiTaRSiCasp9. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028914.
GenevisibleiQ8C3Q0. MM.

Family and domain databases

CDDicd00032. CASc. 1 hit.
Gene3Di1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProiIPR001315. CARD.
IPR033171. Caspase-9.
IPR029030. Caspase-like_dom.
IPR033139. Caspase_cys_AS.
IPR016129. Caspase_his_AS.
IPR011029. DEATH-like_dom.
IPR002138. Pept_C14_p10.
IPR001309. Pept_C14_p20.
IPR015917. Pept_C14A.
IPR017350. Pept_C14A_CASP1-typ.
[Graphical view]
PANTHERiPTHR10454:SF157. PTHR10454:SF157. 1 hit.
PfamiPF00619. CARD. 1 hit.
[Graphical view]
PIRSFiPIRSF038001. Caspase_ICE. 1 hit.
PRINTSiPR00376. IL1BCENZYME.
SMARTiSM00114. CARD. 1 hit.
SM00115. CASc. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF52129. SSF52129. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS01122. CASPASE_CYS. 1 hit.
PS01121. CASPASE_HIS. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8C3Q0_MOUSE
AccessioniPrimary (citable) accession number: Q8C3Q0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.