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Protein

Deleted in autism-related protein 1 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Deleted in autism-related protein 1 homolog
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:1923155. 4930578C19Rik.

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333Sequence AnalysisAdd
BLAST
Chaini34 – 435402Deleted in autism-related protein 1 homologPRO_0000353115Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi102 – 1021N-linked (GlcNAc...)Sequence Analysis
Glycosylationi395 – 3951N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ8C3I9.

Expressioni

Gene expression databases

BgeeiQ8C3I9.
ExpressionAtlasiQ8C3I9. baseline.
GenevestigatoriQ8C3I9.

Structurei

3D structure databases

ProteinModelPortaliQ8C3I9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DIA1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG119995.
GeneTreeiENSGT00520000055625.
HOGENOMiHOG000112102.
HOVERGENiHBG104916.
InParanoidiQ8C3I9.
OMAiYKDIFSC.
OrthoDBiEOG7DRJ40.
TreeFamiTF353643.

Family and domain databases

InterProiIPR022049. FAM69_kinase_dom.
IPR020519. UPF0672.
[Graphical view]
PfamiPF12260. PIP49_C. 1 hit.
[Graphical view]
ProDomiPD307452. UPF0672. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8C3I9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESQWRGAAA TAFHQHWLAR LLLWVSTLSC SFSLPASLPP SLVPRVRSSY
60 70 80 90 100
TMGKTFLGLD KCNACIGTSI CKKFFKEEIR FDNSLASHLG LPPQDLHSYA
110 120 130 140 150
ANYSDDSKTW RPVEISQLVS RYQIEISDRR ICASVSAPKT CSIERILQKT
160 170 180 190 200
GRFQKWLQAK RLTPDLVQGL PSPFLRCPSQ RLLDRVVRRY AEVVDAGSIF
210 220 230 240 250
MDHFTAGDKL RLLYTLAVNA HPIILQIFPG AEGWPMPRYL GSCGRFLVST
260 270 280 290 300
STRPLQEFYD ASPEQAADLA YQLLRVLESL RSNDLNYFFY FTHVDAGMFG
310 320 330 340 350
IFDNGHLFIR DASALGIIDK QEGSQAAART GENEDIFSCL VSDCQIQLSS
360 370 380 390 400
CDTVPEKQSL VLVCQQLLPQ LLQGKFPSPV QKEIDSALSL CSKDNSTDLE
410 420 430
VLGATSWLKD ILRSLRTCDP RFAYRYPDCK YNDRF
Length:435
Mass (Da):49,042
Last modified:March 1, 2003 - v1
Checksum:i0A1B466BB04CEB1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK085770 mRNA. Translation: BAC39535.1.
BX004855, AL732451 Genomic DNA. Translation: CAM17729.1.
AL732451, BX004855 Genomic DNA. Translation: CAM27156.1.
CH466584 Genomic DNA. Translation: EDL35730.1.
BC118515 mRNA. Translation: AAI18516.1.
CCDSiCCDS30038.1.
RefSeqiNP_780437.1. NM_175228.3.
UniGeneiMm.159617.

Genome annotation databases

EnsembliENSMUST00000044188; ENSMUSP00000046567; ENSMUSG00000037358.
GeneIDi75905.
KEGGimmu:75905.
UCSCiuc009ssp.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK085770 mRNA. Translation: BAC39535.1.
BX004855, AL732451 Genomic DNA. Translation: CAM17729.1.
AL732451, BX004855 Genomic DNA. Translation: CAM27156.1.
CH466584 Genomic DNA. Translation: EDL35730.1.
BC118515 mRNA. Translation: AAI18516.1.
CCDSiCCDS30038.1.
RefSeqiNP_780437.1. NM_175228.3.
UniGeneiMm.159617.

3D structure databases

ProteinModelPortaliQ8C3I9.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ8C3I9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044188; ENSMUSP00000046567; ENSMUSG00000037358.
GeneIDi75905.
KEGGimmu:75905.
UCSCiuc009ssp.1. mouse.

Organism-specific databases

MGIiMGI:1923155. 4930578C19Rik.

Phylogenomic databases

eggNOGiNOG119995.
GeneTreeiENSGT00520000055625.
HOGENOMiHOG000112102.
HOVERGENiHBG104916.
InParanoidiQ8C3I9.
OMAiYKDIFSC.
OrthoDBiEOG7DRJ40.
TreeFamiTF353643.

Miscellaneous databases

NextBioi344231.

Gene expression databases

BgeeiQ8C3I9.
ExpressionAtlasiQ8C3I9. baseline.
GenevestigatoriQ8C3I9.

Family and domain databases

InterProiIPR022049. FAM69_kinase_dom.
IPR020519. UPF0672.
[Graphical view]
PfamiPF12260. PIP49_C. 1 hit.
[Graphical view]
ProDomiPD307452. UPF0672. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Heart.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiDIA1R_MOUSE
AccessioniPrimary (citable) accession number: Q8C3I9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 4, 2008
Last sequence update: March 1, 2003
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.