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Q8C350

- Q8C350_MOUSE

UniProt

Q8C350 - Q8C350_MOUSE

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Protein
Submitted name:

Tumor necrosis factor receptor superfamily member 6

Gene

Fas

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. activation-induced cell death of T cells Source: MGI
  2. apoptotic process Source: MGI
  3. apoptotic signaling pathway Source: MGI
  4. B cell mediated immunity Source: MGI
  5. cellular response to lithium ion Source: MGI
  6. extrinsic apoptotic signaling pathway Source: MGI
  7. extrinsic apoptotic signaling pathway in absence of ligand Source: MGI
  8. extrinsic apoptotic signaling pathway via death domain receptors Source: MGI
  9. gene expression Source: MGI
  10. hepatocyte apoptotic process Source: MGI
  11. immunoglobulin production Source: MGI
  12. inflammatory cell apoptotic process Source: MGI
  13. motor neuron apoptotic process Source: MGI
  14. necroptotic signaling pathway Source: MGI
  15. negative regulation of apoptotic process Source: MGI
  16. negative regulation of B cell activation Source: MGI
  17. negative thymic T cell selection Source: MGI
  18. neuron apoptotic process Source: MGI
  19. positive regulation of extrinsic apoptotic signaling pathway in absence of ligand Source: MGI
  20. protein homooligomerization Source: MGI
  21. regulation of lymphocyte differentiation Source: MGI
  22. regulation of myeloid cell differentiation Source: MGI
  23. renal system process Source: MGI
  24. response to glucocorticoid Source: MGI
  25. response to toxic substance Source: MGI
  26. spleen development Source: MGI
  27. T cell homeostasis Source: MGI
  28. transformed cell apoptotic process Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor superfamily member 6Imported
Gene namesi
Name:FasImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 19

Organism-specific databases

MGIiMGI:95484. Fas.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: MGI
  2. external side of plasma membrane Source: MGI
  3. extracellular region Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8C350.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00730000111280.
HOGENOMiHOG000139681.
KOiK04390.

Sequencei

Sequence statusi: Complete.

Q8C350-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLWIWAVLPL VLAGSQLRVH TQGTNSISES LKLRRRVRET DKNCSEGLYQ
60
GGPFCCQPCQ PEN
Length:63
Mass (Da):7,116
Last modified:March 1, 2003 - v1
Checksum:i37283F7401ECAD82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102285 Genomic DNA. No translation available.
AK086933 mRNA. Translation: BAC39766.1.
RefSeqiNP_001140180.1. NM_001146708.1.
UniGeneiMm.1626.

Genome annotation databases

EnsembliENSMUST00000112472; ENSMUSP00000108091; ENSMUSG00000024778.
GeneIDi14102.
KEGGimmu:14102.
UCSCiuc008hgh.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102285 Genomic DNA. No translation available.
AK086933 mRNA. Translation: BAC39766.1 .
RefSeqi NP_001140180.1. NM_001146708.1.
UniGenei Mm.1626.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000112472 ; ENSMUSP00000108091 ; ENSMUSG00000024778 .
GeneIDi 14102.
KEGGi mmu:14102.
UCSCi uc008hgh.2. mouse.

Organism-specific databases

CTDi 355.
MGIi MGI:95484. Fas.

Phylogenomic databases

GeneTreei ENSGT00730000111280.
HOGENOMi HOG000139681.
KOi K04390.

Miscellaneous databases

NextBioi 285130.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8C350.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8C350_MOUSE
AccessioniPrimary (citable) accession number: Q8C350
Secondary accession number(s): D3Z6E5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 26, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3