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Q8C350

- Q8C350_MOUSE

UniProt

Q8C350 - Q8C350_MOUSE

Protein
Submitted name:

Tumor necrosis factor receptor superfamily member 6

Gene

Fas

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. activation-induced cell death of T cells Source: MGI
    2. apoptotic process Source: MGI
    3. apoptotic signaling pathway Source: MGI
    4. B cell mediated immunity Source: MGI
    5. cellular response to lithium ion Source: MGI
    6. extrinsic apoptotic signaling pathway Source: MGI
    7. extrinsic apoptotic signaling pathway in absence of ligand Source: MGI
    8. extrinsic apoptotic signaling pathway via death domain receptors Source: MGI
    9. gene expression Source: MGI
    10. hepatocyte apoptotic process Source: MGI
    11. immunoglobulin production Source: MGI
    12. inflammatory cell apoptotic process Source: MGI
    13. motor neuron apoptotic process Source: MGI
    14. necroptotic signaling pathway Source: MGI
    15. negative regulation of apoptotic process Source: MGI
    16. negative regulation of B cell activation Source: MGI
    17. negative thymic T cell selection Source: MGI
    18. neuron apoptotic process Source: MGI
    19. positive regulation of extrinsic apoptotic signaling pathway in absence of ligand Source: MGI
    20. protein homooligomerization Source: MGI
    21. regulation of lymphocyte differentiation Source: MGI
    22. regulation of myeloid cell differentiation Source: MGI
    23. renal system process Source: MGI
    24. response to glucocorticoid Source: MGI
    25. response to toxic substance Source: MGI
    26. spleen development Source: MGI
    27. T cell homeostasis Source: MGI
    28. transformed cell apoptotic process Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Tumor necrosis factor receptor superfamily member 6Imported
    Gene namesi
    Name:FasImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 19

    Organism-specific databases

    MGIiMGI:95484. Fas.

    Subcellular locationi

    GO - Cellular componenti

    1. cell surface Source: MGI
    2. external side of plasma membrane Source: MGI
    3. extracellular region Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ8C350.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00730000111280.
    HOGENOMiHOG000139681.
    InParanoidiQ8C350.
    KOiK04390.

    Sequencei

    Sequence statusi: Complete.

    Q8C350-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLWIWAVLPL VLAGSQLRVH TQGTNSISES LKLRRRVRET DKNCSEGLYQ   50
    GGPFCCQPCQ PEN 63
    Length:63
    Mass (Da):7,116
    Last modified:March 1, 2003 - v1
    Checksum:i37283F7401ECAD82
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102285 Genomic DNA. No translation available.
    AK086933 mRNA. Translation: BAC39766.1.
    RefSeqiNP_001140180.1. NM_001146708.1.
    UniGeneiMm.1626.

    Genome annotation databases

    EnsembliENSMUST00000112472; ENSMUSP00000108091; ENSMUSG00000024778.
    GeneIDi14102.
    KEGGimmu:14102.
    UCSCiuc008hgh.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102285 Genomic DNA. No translation available.
    AK086933 mRNA. Translation: BAC39766.1 .
    RefSeqi NP_001140180.1. NM_001146708.1.
    UniGenei Mm.1626.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000112472 ; ENSMUSP00000108091 ; ENSMUSG00000024778 .
    GeneIDi 14102.
    KEGGi mmu:14102.
    UCSCi uc008hgh.2. mouse.

    Organism-specific databases

    CTDi 355.
    MGIi MGI:95484. Fas.

    Phylogenomic databases

    GeneTreei ENSGT00730000111280.
    HOGENOMi HOG000139681.
    InParanoidi Q8C350.
    KOi K04390.

    Miscellaneous databases

    ChiTaRSi FAS. mouse.
    NextBioi 285130.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8C350.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    10. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8C350_MOUSE
    AccessioniPrimary (citable) accession number: Q8C350
    Secondary accession number(s): D3Z6E5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3