Unreviewed, UniProtKB/TrEMBL Q8C2P1 (Q8C2P1_MOUSE)

Names and origin

Protein names

Submitted name:
    Putative uncharacterized protein EMBL BAC40236.1

Gene names

Name:

Smad2 MGI 108051

Organism

Mus musculus (Mouse) EMBL BAC40236.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	64 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	SMAD protein complex assembly Inferred from electronic annotation. Source: Compara anterior/posterior pattern formation Inferred from mutant phenotype. Source: MGI cell fate commitment Inferred from mutant phenotype. Source: MGI developmental growth Inferred from genetic interaction. Source: MGI embryonic cranial skeleton morphogenesis Inferred from genetic interaction. Source: MGI embryonic foregut morphogenesis Inferred from genetic interaction. Source: MGI endoderm development Inferred from genetic interaction. Source: MGI heart development Inferred from genetic interaction. Source: MGI in utero embryonic development Inferred from genetic interaction. Source: MGI insulin secretion Inferred from genetic interaction. Source: MGI intracellular signaling cascade Inferred from direct assay. Source: MGI lung development Inferred from genetic interaction. Source: MGI mesoderm formation Inferred from mutant phenotype. Source: MGI negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara organ growth Inferred from genetic interaction. Source: MGI pancreas development Inferred from genetic interaction. Source: MGI paraxial mesoderm morphogenesis Inferred from mutant phenotype. Source: MGI pericardium development Inferred from genetic interaction. Source: MGI positive regulation of transcription from RNA polymerase II promoter Inferred from direct assay. Source: MGI post-embryonic development Inferred from genetic interaction. Source: MGI protein amino acid phosphorylation Inferred from direct assay. Source: MGI regulation of binding Inferred from direct assay. Source: MGI regulation of transforming growth factor beta receptor signaling pathway Inferred from electronic annotation. Source: Compara response to cholesterol Inferred from electronic annotation. Source: Compara response to glucose stimulus Inferred from genetic interaction. Source: MGI transforming growth factor beta receptor signaling pathway Inferred from direct assay. Source: MGI zygotic specification of dorsal/ventral axis Inferred from electronic annotation. Source: Compara
Cellular component	activin responsive factor complex Inferred from electronic annotation. Source: Compara cytoplasm Inferred from direct assay. Source: MGI
Molecular function	R-SMAD binding Inferred from electronic annotation. Source: Compara chromatin binding Inferred from direct assay. Source: MGI co-SMAD binding Inferred from electronic annotation. Source: Compara double-stranded DNA binding Inferred from direct assay. Source: MGI promoter binding Inferred from electronic annotation. Source: Compara transcription activator activity Inferred from direct assay. Source: MGI transcription factor binding Inferred from physical interaction. Source: MGI transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Inferred from electronic annotation. Source: Compara type I transforming growth factor beta receptor binding Inferred from electronic annotation. Source: Compara ubiquitin protein ligase binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAC40236.1

Sequences

	Sequence		Length	Mass (Da)
	Q8C2P1-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 91C31D07B6836035	FASTA	64	7,338
	10 20 30 40 50 60 AVYQLTRMCT IRMSFVKGWG AEYRRQTVTS TPCWIELHLN GPLQWLDKVL TQMGSPSVRC SSMS

References

[1]

"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: NOD EMBL BAC40236.1. Tissue: Thymus EMBL BAC40236.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK088249 mRNA. Translation: BAC40236.1.
IPI	IPI00458087.
UniGene	Mm.391091
3D structure databases
HSSP	HSSP built from PDB template 1DEV based on UniProtKB Q15796.
SMR	Q8C2P1. Positions 1-64.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8C2P1.
Genome annotation databases
Ensembl	ENSMUST00000025453; ENSMUSP00000025453; ENSMUSG00000024563; Mus musculus. [Genome view] ENSMUST00000091831; ENSMUSP00000089439; ENSMUSG00000024563; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:108051. Smad2.
Phylogenomic databases
HOVERGEN	Q8C2P1.
InParanoid	Q8C2P1.
Gene expression databases
ArrayExpress	Q8C2P1.
Bgee	Q8C2P1.
Genevestigator	Q8C2P1.
Family and domain databases
InterPro	IPR013790. Dwarfin. IPR017855. SMAD_dom-like. IPR001132. SMAD_dom_Dwarfin-type. IPR008984. SMAD_FHA_domain. [Graphical view]
Gene3D	G3DSA:2.60.200.10. MH2_Dwarfin-type. 1 hit.
PANTHER	PTHR13703. Dwarfin. 1 hit.
Pfam	PF03166. MH2. 1 hit. [Graphical view]
PROSITE	PS51076. MH2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q8C2P1_MOUSE

Accession

Primary (citable) accession number: Q8C2P1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 19, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)