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Protein

Galectin

Gene

Lgals3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandLectinUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Recommended name:
GalectinUniRule annotation
Gene namesi
Name:Lgals3Imported
ORF Names:mCG_6908Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:96778. Lgals3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000050335.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ8C253. 1 interactor.
MINTiMINT-4114132.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini132 – 262GalectinInterPro annotationAdd BLAST131

Phylogenomic databases

eggNOGiKOG3587. Eukaryota.
ENOG4111EA0. LUCA.
GeneTreeiENSGT00760000119105.
HOGENOMiHOG000246423.
HOVERGENiHBG006255.
KOiK06831.
OMAiSASHAMI.
OrthoDBiEOG091G0WP8.
TreeFamiTF315551.

Family and domain databases

CDDicd00070. GLECT. 1 hit.
InterProiView protein in InterPro
IPR013320. ConA-like_dom.
IPR015534. Galectin_3.
IPR001079. Galectin_CRD.
PANTHERiPTHR11346:SF145. PTHR11346:SF145. 1 hit.
PfamiView protein in Pfam
PF00337. Gal-bind_lectin. 1 hit.
SMARTiView protein in SMART
SM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiView protein in PROSITE
PS51304. GALECTIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8C253-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSFSLNDA LAGSGNPNPQ GYPGAWGNQP GAGGYPGAAY PGAYPGQAPP
60 70 80 90 100
GAYPGQAPPG AYPGQAPPSA YPGPTAPGAY PGPTAPGAYP GSTAPGAFPG
110 120 130 140 150
QPGAPGAYPS APGGYPAAGP YGVPAGPLTV PYDLPLPGGV MPRMLITIMG
160 170 180 190 200
TVKPNANRIV LDFRRGNDVA FHFNPRFNEN NRRVIVCNTK QDNNWGKEER
210 220 230 240 250
QSAFPFESGK PFKIQVLVEA DHFKVAVNDA HLLQYNHRMK NLREISQLGI
260
SGDITLTSAN HAMI
Length:264
Mass (Da):27,415
Last modified:March 1, 2003 - v1
Checksum:i253A4F8037143740
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123665 Genomic DNA. No translation available.
BC132328 mRNA. Translation: AAI32329.1.
BC138790 mRNA. Translation: AAI38791.1.
BC145419 mRNA. Translation: AAI45420.1.
AK089249 mRNA. Translation: BAC40813.1.
AK149783 mRNA. Translation: BAE29081.1.
AK155484 mRNA. Translation: BAE33287.1.
AK159536 mRNA. Translation: BAE35163.1.
AK170803 mRNA. Translation: BAE42038.1.
CH466605 Genomic DNA. Translation: EDL20742.1.
CH466605 Genomic DNA. Translation: EDL20745.1.
PIRiA45983.
RefSeqiNP_001139425.1. NM_001145953.1.
NP_034835.1. NM_010705.3.
UniGeneiMm.248615.

Genome annotation databases

EnsembliENSMUST00000142734; ENSMUSP00000118169; ENSMUSG00000050335.
ENSMUST00000146468; ENSMUSP00000119275; ENSMUSG00000050335.
ENSMUST00000150290; ENSMUSP00000114350; ENSMUSG00000050335.
GeneIDi16854.
KEGGimmu:16854.
UCSCiuc007tia.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8C253_MOUSE
AccessioniPrimary (citable) accession number: Q8C253
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 27, 2017
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported