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Protein
Submitted name:

Uncharacterized protein

Gene

Ctsd

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei97PROSITE-ProRule annotation1
Active sitei293PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotation, Hydrolase, Protease

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CtsdImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88562 Ctsd

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500430609921 – 445Sequence analysisAdd BLAST425

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiQ8C243
PeptideAtlasiQ8C243
PRIDEiQ8C243

Interactioni

Protein-protein interaction databases

IntActiQ8C243, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ8C243
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 403Peptidase A1InterPro annotationAdd BLAST325

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
HOGENOMiHOG000197681
HOVERGENiHBG000482
PhylomeDBiQ8C243

Family and domain databases

Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR012848 Aspartic_peptidase_N
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF07966 A1_Propeptide, 1 hit
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 2 hits
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Complete.

Q8C243-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTPGVLLLI LGLLASSSFA IIRIPLRKFT SIRRTMTEVG GSVEDLILKG
60 70 80 90 100
PITKYSMQSS PKTTEPVSEL LKNYLDAQYY GDIGIGTPPQ CFTVVFDTGS
110 120 130 140 150
SNLWVPSIHC KILDIACWVH HKYNSDKSST YVKNGTSFDI HYGSGSLSGY
160 170 180 190 200
LSQDTVSVPC KSDQSKARGI KVEKQIFGEA TKQPGIVFVA AKFDGILGMG
210 220 230 240 250
YPHISVNNVL PVFDNLMQQK LVDKNIFSFY LNRDPEGQPG GELMLGGTDS
260 270 280 290 300
KYYHGELSYL NVTRKAYWQV HMDQLEVGNE LTLCKGGCEA IVDTGTSLLV
310 320 330 340 350
GPVEEVKELQ KAIGAVPLIQ GEYMIPCEKV SSLPTVYLKL GGKNYELHPD
360 370 380 390 400
KYILKVSQGG KTICLSGFMG MDIPPPSGPL WILAMSSLVP TTLCLTETTI
410 420 430 440
GSALPMLSYS NLLLLHCQGT GSESSRGSQP APSLHLPHSH IVTLA
Length:445
Mass (Da):48,374
Last modified:March 1, 2003 - v1
Checksum:i745434E92C1450C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK089294 mRNA Translation: BAC40831.1
UniGeneiMm.231395

Similar proteinsi

Entry informationi

Entry nameiQ8C243_MOUSE
AccessioniPrimary (citable) accession number: Q8C243
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health