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Protein
Submitted name:

Alpha-defensin 2

Gene

Defa33

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionAntibioticSAAS annotation, Antimicrobial, DefensinSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-defensin 2Imported
Submitted name:
Defensin, alpha, 33Imported
Submitted name:
Defensin-related cryptdin 20Imported
Gene namesi
Name:Defa33Imported
Synonyms:Defa2Imported, Defcr20Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:94882. Defa2.
MGI:5434357. Defa33.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501142792820 – 95Sequence analysisAdd BLAST76

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000094362.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129593.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 89DEFSNInterPro annotationAdd BLAST26

Sequence similaritiesi

Belongs to the alpha-defensin family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JFE2. Eukaryota.
ENOG4111A2R. LUCA.
GeneTreeiENSGT00900000141425.
HOVERGENiHBG011703.
KOiK05230.
OrthoDBiEOG091G12GE.
TreeFamiTF338414.

Family and domain databases

InterProiView protein in InterPro
IPR016327. Alpha-defensin_pro.
IPR006080. Defensin_beta/alpha.
IPR002366. Defensin_propep.
PANTHERiPTHR11876. PTHR11876. 1 hit.
PfamiView protein in Pfam
PF00879. Defensin_propep. 1 hit.
PIRSFiPIRSF001875. Alpha-defensin. 1 hit.
SMARTiView protein in SMART
SM00048. DEFSN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8C1N9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLVLLSAL VLLAFQVQAD PIQNTDEETN TEEQAGEEDQ AVSVSFGDPE
60 70 80 90
GSALHEKSSR DLICYCRKGG CNRGEQVYGT CSGRLLFCCR RRHRH
Length:95
Mass (Da):10,575
Last modified:March 1, 2003 - v1
Checksum:i5CC24F6A227FF7D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC240396 Genomic DNA. No translation available.
AY746425 mRNA. Translation: AAW78334.1.
AK008459 mRNA. Translation: BAC25221.1.
RefSeqiNP_001182563.2. NM_001195634.2.
NP_001257484.1. NM_001270555.1.
UniGeneiMm.327348.
Mm.423382.
Mm.425522.

Genome annotation databases

EnsembliENSMUST00000120874; ENSMUSP00000129593; ENSMUSG00000094362.
ENSMUST00000170275; ENSMUSP00000125888; ENSMUSG00000096295.
GeneIDi100294660.
100505096.
KEGGimmu:100294660.
mmu:100505096.
UCSCiuc029wrp.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8C1N9_MOUSE
AccessioniPrimary (citable) accession number: Q8C1N9
Secondary accession number(s): E9Q4S6, E9Q5P7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported