Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Paraneoplastic antigen Ma1 homolog

Gene

Pnma1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Paraneoplastic antigen Ma1 homolog
Gene namesi
Name:Pnma1
Synonyms:Ma1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:2180564. Pnma1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001552001 – 353Paraneoplastic antigen Ma1 homologAdd BLAST353

Proteomic databases

PaxDbiQ8C1C8.
PRIDEiQ8C1C8.

PTM databases

PhosphoSitePlusiQ8C1C8.

Expressioni

Tissue specificityi

Predominantly expressed in testis. Very low levels in the brain, including in the piriform cortex, hippocampus and some subcortical nuclei.1 Publication

Gene expression databases

BgeeiENSMUSG00000054383.
CleanExiMM_PNMA1.
GenevisibleiQ8C1C8. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000060783.

Structurei

3D structure databases

ProteinModelPortaliQ8C1C8.
SMRiQ8C1C8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi336 – 341Poly-Glu6

Sequence similaritiesi

Belongs to the PNMA family.Curated

Phylogenomic databases

eggNOGiENOG410IIH9. Eukaryota.
ENOG410YK5I. LUCA.
GeneTreeiENSGT00530000062986.
HOGENOMiHOG000013079.
HOVERGENiHBG052488.
InParanoidiQ8C1C8.
OMAiEHTNEVM.
OrthoDBiEOG091G0BG9.
TreeFamiTF335054.

Family and domain databases

InterProiIPR026523. PNMA.
IPR026528. PNMA1.
[Graphical view]
PANTHERiPTHR23095. PTHR23095. 1 hit.
PTHR23095:SF17. PTHR23095:SF17. 1 hit.
PfamiPF14893. PNMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8C1C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMTLLEDWC RGMDVNSQRA LLVWGIPVNC DETEIEETLQ AAMPQVSYRV
60 70 80 90 100
LGRMFWREEN AKAALLELTG AVDYSLIPRE MPGKGGLWKV VFKPPTSDAV
110 120 130 140 150
FLERLHLFLA REGWTVQDVA RVLGFQNPAP APGPEMPAEM LNYILDNVIQ
160 170 180 190 200
PLVESIWYKK LTLFSGKDIP GPGEETFDSW LEHSNEIIEE WQVSDIEKRR
210 220 230 240 250
RLMESLRGPA ADVIRILKTN NAAITTAECL KALEQVFGSV ESSRDAQVRF
260 270 280 290 300
LNTYQNPGEK LSSYVIRLEP LLQKVVDKGV IDKDNVNQAR LEQVIAGANH
310 320 330 340 350
SGALRRQLWL AGAEEGPAPN LFQLLVQIRE EEAKKEEEEA EAALLQLGLE

GHF
Length:353
Mass (Da):39,718
Last modified:July 27, 2011 - v2
Checksum:iF7B27378B8469675
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti136M → T in BAC25885 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017476 mRNA. Translation: BAB30762.1.
AK028331 mRNA. Translation: BAC25885.1.
AK136933 mRNA. Translation: BAE23177.1.
CH466590 Genomic DNA. Translation: EDL02765.1.
BC116687 mRNA. Translation: AAI16688.1.
BC116688 mRNA. Translation: AAI16689.1.
CCDSiCCDS26040.1.
RefSeqiNP_081714.2. NM_027438.3.
UniGeneiMm.444348.

Genome annotation databases

EnsembliENSMUST00000061425; ENSMUSP00000060783; ENSMUSG00000054383.
GeneIDi70481.
KEGGimmu:70481.
UCSCiuc007oel.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017476 mRNA. Translation: BAB30762.1.
AK028331 mRNA. Translation: BAC25885.1.
AK136933 mRNA. Translation: BAE23177.1.
CH466590 Genomic DNA. Translation: EDL02765.1.
BC116687 mRNA. Translation: AAI16688.1.
BC116688 mRNA. Translation: AAI16689.1.
CCDSiCCDS26040.1.
RefSeqiNP_081714.2. NM_027438.3.
UniGeneiMm.444348.

3D structure databases

ProteinModelPortaliQ8C1C8.
SMRiQ8C1C8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000060783.

PTM databases

PhosphoSitePlusiQ8C1C8.

Proteomic databases

PaxDbiQ8C1C8.
PRIDEiQ8C1C8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000061425; ENSMUSP00000060783; ENSMUSG00000054383.
GeneIDi70481.
KEGGimmu:70481.
UCSCiuc007oel.1. mouse.

Organism-specific databases

CTDi9240.
MGIiMGI:2180564. Pnma1.

Phylogenomic databases

eggNOGiENOG410IIH9. Eukaryota.
ENOG410YK5I. LUCA.
GeneTreeiENSGT00530000062986.
HOGENOMiHOG000013079.
HOVERGENiHBG052488.
InParanoidiQ8C1C8.
OMAiEHTNEVM.
OrthoDBiEOG091G0BG9.
TreeFamiTF335054.

Miscellaneous databases

PROiQ8C1C8.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000054383.
CleanExiMM_PNMA1.
GenevisibleiQ8C1C8. MM.

Family and domain databases

InterProiIPR026523. PNMA.
IPR026528. PNMA1.
[Graphical view]
PANTHERiPTHR23095. PTHR23095. 1 hit.
PTHR23095:SF17. PTHR23095:SF17. 1 hit.
PfamiPF14893. PNMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPNMA1_MOUSE
AccessioniPrimary (citable) accession number: Q8C1C8
Secondary accession number(s): Q3UVU2, Q9CYP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: July 27, 2011
Last modified: November 2, 2016
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.