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Protein

Paraneoplastic antigen Ma1 homolog

Gene

Pnma1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Paraneoplastic antigen Ma1 homolog
Gene namesi
Name:Pnma1
Synonyms:Ma1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:2180564 Pnma1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001552001 – 353Paraneoplastic antigen Ma1 homologAdd BLAST353

Proteomic databases

PaxDbiQ8C1C8
PRIDEiQ8C1C8

PTM databases

PhosphoSitePlusiQ8C1C8

Expressioni

Tissue specificityi

Predominantly expressed in testis. Very low levels in the brain, including in the piriform cortex, hippocampus and some subcortical nuclei.1 Publication

Gene expression databases

BgeeiENSMUSG00000054383
CleanExiMM_PNMA1
GenevisibleiQ8C1C8 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000060783

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi336 – 341Poly-Glu6

Sequence similaritiesi

Belongs to the PNMA family.Curated

Phylogenomic databases

eggNOGiENOG410IIH9 Eukaryota
ENOG410YK5I LUCA
GeneTreeiENSGT00530000062986
HOGENOMiHOG000013079
HOVERGENiHBG052488
InParanoidiQ8C1C8
OMAiEHTNEVM
OrthoDBiEOG091G0BG9
TreeFamiTF335054

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
IPR026528 PNMA1
PANTHERiPTHR23095 PTHR23095, 1 hit
PTHR23095:SF17 PTHR23095:SF17, 1 hit
PfamiView protein in Pfam
PF14893 PNMA, 1 hit

Sequencei

Sequence statusi: Complete.

Q8C1C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMTLLEDWC RGMDVNSQRA LLVWGIPVNC DETEIEETLQ AAMPQVSYRV
60 70 80 90 100
LGRMFWREEN AKAALLELTG AVDYSLIPRE MPGKGGLWKV VFKPPTSDAV
110 120 130 140 150
FLERLHLFLA REGWTVQDVA RVLGFQNPAP APGPEMPAEM LNYILDNVIQ
160 170 180 190 200
PLVESIWYKK LTLFSGKDIP GPGEETFDSW LEHSNEIIEE WQVSDIEKRR
210 220 230 240 250
RLMESLRGPA ADVIRILKTN NAAITTAECL KALEQVFGSV ESSRDAQVRF
260 270 280 290 300
LNTYQNPGEK LSSYVIRLEP LLQKVVDKGV IDKDNVNQAR LEQVIAGANH
310 320 330 340 350
SGALRRQLWL AGAEEGPAPN LFQLLVQIRE EEAKKEEEEA EAALLQLGLE

GHF
Length:353
Mass (Da):39,718
Last modified:July 27, 2011 - v2
Checksum:iF7B27378B8469675
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti136M → T in BAC25885 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017476 mRNA Translation: BAB30762.1
AK028331 mRNA Translation: BAC25885.1
AK136933 mRNA Translation: BAE23177.1
CH466590 Genomic DNA Translation: EDL02765.1
BC116687 mRNA Translation: AAI16688.1
BC116688 mRNA Translation: AAI16689.1
CCDSiCCDS26040.1
RefSeqiNP_081714.2, NM_027438.3
UniGeneiMm.444348

Genome annotation databases

EnsembliENSMUST00000061425; ENSMUSP00000060783; ENSMUSG00000054383
GeneIDi70481
KEGGimmu:70481
UCSCiuc007oel.1 mouse

Similar proteinsi

Entry informationi

Entry nameiPNMA1_MOUSE
AccessioniPrimary (citable) accession number: Q8C1C8
Secondary accession number(s): Q3UVU2, Q9CYP2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: July 27, 2011
Last modified: April 25, 2018
This is version 85 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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