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Q8C190

- VP9D1_MOUSE

UniProt

Q8C190 - VP9D1_MOUSE

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Protein

VPS9 domain-containing protein 1

Gene

Vps9d1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
VPS9 domain-containing protein 1
Alternative name(s):
5-day ovary-specific transcript 1 protein
Gene namesi
Name:Vps9d1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 8

Organism-specific databases

MGIiMGI:1914143. Vps9d1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 649649VPS9 domain-containing protein 1PRO_0000079280Add
BLAST

Proteomic databases

PaxDbiQ8C190.
PRIDEiQ8C190.

PTM databases

PhosphoSiteiQ8C190.

Expressioni

Gene expression databases

BgeeiQ8C190.
CleanExiMM_1300018I17RIK.
ExpressionAtlasiQ8C190. differential.
GenevestigatoriQ8C190.

Interactioni

Protein-protein interaction databases

BioGridi215310. 1 interaction.
STRINGi10090.ENSMUSP00000113748.

Structurei

3D structure databases

ProteinModelPortaliQ8C190.
SMRiQ8C190. Positions 531-639.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini487 – 648162VPS9PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 VPS9 domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG70432.
GeneTreeiENSGT00390000015057.
HOGENOMiHOG000293285.
HOVERGENiHBG062847.
InParanoidiQ8C190.
OrthoDBiEOG7P2XV3.
PhylomeDBiQ8C190.
TreeFamiTF332037.

Family and domain databases

Gene3Di1.20.58.280. 1 hit.
InterProiIPR007330. MIT.
IPR003123. VPS9.
[Graphical view]
PfamiPF02204. VPS9. 1 hit.
[Graphical view]
SUPFAMiSSF116846. SSF116846. 1 hit.
PROSITEiPS51205. VPS9. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8C190-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAAAAGDGGA KPLQSAMKLA NKAIELDTGN RPREAYVEYL RSIHYISQVL
60 70 80 90 100
LEDVENTTEA GETVPPETSK MLKLAEQCLE RAQSTATKLG RICLKPAVPA
110 120 130 140 150
APPTPLPTSR HRRVCSDEGG KLSPFLPPEI FQKLQVAESQ NSKKELTPLE
160 170 180 190 200
KASLQNQKLR ATYEARMARL DPSQAMQKTS LTLSLQRQMM ENLVIAKARE
210 220 230 240 250
ETLQRKMEER RLRLQEAANR RFCSQVALTP EEREQRALYA AILEYEQDHD
260 270 280 290 300
WPKHWRAKLK RSPGDLSLVT SLLSHLLSLP DHPISQLLKK LQCAVYSALY
310 320 330 340 350
PIVSRAATSA APAPGSCSLP PEANGLLAPG SRRLRSSQSL YCMLSPSEPS
360 370 380 390 400
AAPRVLDGPP PTPSVPTLHS GPLDREADGS PAGPSSPLVD ALSHLPDKDS
410 420 430 440 450
SFEDLEQFLA MSEPQTPGAK REPLLECLKS TVKDIHNAID RLLSLTLLAF
460 470 480 490 500
ESLNTATSKD RCLACIEEPF FSPLWPLLLA LYRSVHRTRE AAVSRSMELY
510 520 530 540 550
RNAPPTALGI PTKLLPRVPE AQASTYPYCT AAQELGLLVL ESCPQKKLEC
560 570 580 590 600
IVRTLRVICI CAEDYCRAQE ARPEGESQPP AAAIGADDLL PILSFVVLRS
610 620 630 640
GLPQLVSECA ALEEFTHEGY LIGEEGYCLT SLQSALSYVE LLSRGRLDK
Length:649
Mass (Da):71,284
Last modified:March 1, 2003 - v1
Checksum:i34385AD36C050552
GO
Isoform 2 (identifier: Q8C190-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     552-555: VRTL → GAGI
     556-649: Missing.

Show »
Length:555
Mass (Da):60,914
Checksum:i3D78A45279606553
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei552 – 5554VRTL → GAGI in isoform 2. 1 PublicationVSP_014703
Alternative sequencei556 – 64994Missing in isoform 2. 1 PublicationVSP_014704Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY751521 mRNA. Translation: AAV30827.1.
AK028751 mRNA. Translation: BAC26098.1.
BC057621 mRNA. Translation: AAH57621.1.
CCDSiCCDS52698.1. [Q8C190-1]
RefSeqiNP_082476.1. NM_028200.1. [Q8C190-1]
UniGeneiMm.276193.

Genome annotation databases

EnsembliENSMUST00000122363; ENSMUSP00000113575; ENSMUSG00000001062. [Q8C190-1]
GeneIDi72325.
KEGGimmu:72325.
UCSCiuc009nuv.2. mouse. [Q8C190-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY751521 mRNA. Translation: AAV30827.1 .
AK028751 mRNA. Translation: BAC26098.1 .
BC057621 mRNA. Translation: AAH57621.1 .
CCDSi CCDS52698.1. [Q8C190-1 ]
RefSeqi NP_082476.1. NM_028200.1. [Q8C190-1 ]
UniGenei Mm.276193.

3D structure databases

ProteinModelPortali Q8C190.
SMRi Q8C190. Positions 531-639.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 215310. 1 interaction.
STRINGi 10090.ENSMUSP00000113748.

PTM databases

PhosphoSitei Q8C190.

Proteomic databases

PaxDbi Q8C190.
PRIDEi Q8C190.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000122363 ; ENSMUSP00000113575 ; ENSMUSG00000001062 . [Q8C190-1 ]
GeneIDi 72325.
KEGGi mmu:72325.
UCSCi uc009nuv.2. mouse. [Q8C190-1 ]

Organism-specific databases

CTDi 9605.
MGIi MGI:1914143. Vps9d1.

Phylogenomic databases

eggNOGi NOG70432.
GeneTreei ENSGT00390000015057.
HOGENOMi HOG000293285.
HOVERGENi HBG062847.
InParanoidi Q8C190.
OrthoDBi EOG7P2XV3.
PhylomeDBi Q8C190.
TreeFami TF332037.

Miscellaneous databases

NextBioi 336024.
SOURCEi Search...

Gene expression databases

Bgeei Q8C190.
CleanExi MM_1300018I17RIK.
ExpressionAtlasi Q8C190. differential.
Genevestigatori Q8C190.

Family and domain databases

Gene3Di 1.20.58.280. 1 hit.
InterProi IPR007330. MIT.
IPR003123. VPS9.
[Graphical view ]
Pfami PF02204. VPS9. 1 hit.
[Graphical view ]
SUPFAMi SSF116846. SSF116846. 1 hit.
PROSITEi PS51205. VPS9. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of differentially expressed transcripts between 1 day ovary and 5 day ovary."
    Park C.E., Hwang K.C., Kim N.H., Lee K.A.
    Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Strain: ICR.
    Tissue: Ovary.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: C57BL/6J.
    Tissue: Skin.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: C57BL/6.
    Tissue: Embryonic brain.

Entry informationi

Entry nameiVP9D1_MOUSE
AccessioniPrimary (citable) accession number: Q8C190
Secondary accession number(s): Q6PFD1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3