##gff-version 3
Q8C180	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8C180	UniProtKB	Chain	2	508	.	.	.	ID=PRO_0000087345;Note=Fibroblast growth factor receptor substrate 2	
Q8C180	UniProtKB	Domain	13	115	.	.	.	Note=IRS-type PTB;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00389	
Q8C180	UniProtKB	Region	116	180	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8C180	UniProtKB	Region	201	243	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8C180	UniProtKB	Region	268	298	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8C180	UniProtKB	Region	315	345	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8C180	UniProtKB	Region	441	467	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8C180	UniProtKB	Region	483	508	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8C180	UniProtKB	Compositional bias	128	144	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8C180	UniProtKB	Modified residue	177	177	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8WU20	
Q8C180	UniProtKB	Modified residue	196	196	.	.	.	Note=Phosphotyrosine%3B by FGFR1;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11353842,ECO:0000269|PubMed:9182757,ECO:0000269|PubMed:9632781;Dbxref=PMID:11353842,PMID:9182757,PMID:9632781	
Q8C180	UniProtKB	Modified residue	211	211	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:19144319;Dbxref=PMID:19144319	
Q8C180	UniProtKB	Modified residue	221	221	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8WU20	
Q8C180	UniProtKB	Modified residue	306	306	.	.	.	Note=Phosphotyrosine%3B by FGFR1;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11353842,ECO:0000269|PubMed:9182757,ECO:0000269|PubMed:9632781;Dbxref=PMID:11353842,PMID:9182757,PMID:9632781	
Q8C180	UniProtKB	Modified residue	349	349	.	.	.	Note=Phosphotyrosine%3B by FGFR1;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0007744;evidence=ECO:0000269|PubMed:11353842,ECO:0000269|PubMed:9182757,ECO:0000269|PubMed:9632781,ECO:0007744|PubMed:19131326;Dbxref=PMID:11353842,PMID:19131326,PMID:9182757,PMID:9632781	
Q8C180	UniProtKB	Modified residue	365	365	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8WU20	
Q8C180	UniProtKB	Modified residue	392	392	.	.	.	Note=Phosphotyrosine%3B by FGFR1;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11353842,ECO:0000269|PubMed:9182757,ECO:0000269|PubMed:9632781;Dbxref=PMID:11353842,PMID:9182757,PMID:9632781	
Q8C180	UniProtKB	Modified residue	436	436	.	.	.	Note=Phosphotyrosine%3B by FGFR1;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11353842,ECO:0000269|PubMed:9632781;Dbxref=PMID:11353842,PMID:9632781	
Q8C180	UniProtKB	Modified residue	471	471	.	.	.	Note=Phosphotyrosine%3B by FGFR1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11353842;Dbxref=PMID:11353842	
Q8C180	UniProtKB	Lipidation	2	2	.	.	.	Note=N-myristoyl glycine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9182757;Dbxref=PMID:9182757	
Q8C180	UniProtKB	Mutagenesis	2	2	.	.	.	Note=Abolishes myristoylation and membrane association. G->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9182757;Dbxref=PMID:9182757	
Q8C180	UniProtKB	Mutagenesis	196	196	.	.	.	Note=Abolishes tyrosine phosphorylation and interactions with GRB2 and PTPN11%3B when associated with F-306%3B F-349%3B F-392 and F-436. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9182757;Dbxref=PMID:9182757	
Q8C180	UniProtKB	Mutagenesis	306	306	.	.	.	Note=Abolishes tyrosine phosphorylation and interactions with GRB2 and PTPN11%3B when associated with F-196%3B F-349%3B F-392 and F-436. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9182757;Dbxref=PMID:9182757	
Q8C180	UniProtKB	Mutagenesis	349	349	.	.	.	Note=Abolishes tyrosine phosphorylation and interactions with GRB2 and PTPN11%3B when associated with F-196%3B F-306%3B F-392 and F-436. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9182757;Dbxref=PMID:9182757	
Q8C180	UniProtKB	Mutagenesis	392	392	.	.	.	Note=Abolishes tyrosine phosphorylation and interactions with GRB2 and PTPN11%3B when associated with F-196%3B F-306%3B F-349 and F-436. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9182757;Dbxref=PMID:9182757	
Q8C180	UniProtKB	Mutagenesis	436	436	.	.	.	Note=Abolishes tyrosine phosphorylation and interactions with GRB2 and PTPN11%3B when associated with F-196%3B F-306%3B F-349 and F-392. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9632781;Dbxref=PMID:9632781