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Q8BZR0

- GPR82_MOUSE

UniProt

Q8BZR0 - GPR82_MOUSE

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Protein
Probable G-protein coupled receptor 82
Gene
Gpr82
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable G-protein coupled receptor 82
    Gene namesi
    Name:Gpr82
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:2441734. Gpr82.

    Subcellular locationi

    Topology

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 1111Extracellular Reviewed prediction
    Add
    BLAST
    Transmembranei12 – 3221Helical; Name=1; Reviewed prediction
    Add
    BLAST
    Topological domaini33 – 5523Cytoplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei56 – 7621Helical; Name=2; Reviewed prediction
    Add
    BLAST
    Topological domaini77 – 9216Extracellular Reviewed prediction
    Add
    BLAST
    Transmembranei93 – 11523Helical; Name=3; Reviewed prediction
    Add
    BLAST
    Topological domaini116 – 15641Cytoplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei157 – 17721Helical; Name=4; Reviewed prediction
    Add
    BLAST
    Topological domaini178 – 19720Extracellular Reviewed prediction
    Add
    BLAST
    Transmembranei198 – 21821Helical; Name=5; Reviewed prediction
    Add
    BLAST
    Topological domaini219 – 25133Cytoplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei252 – 27221Helical; Name=6; Reviewed prediction
    Add
    BLAST
    Topological domaini273 – 32856Extracellular Reviewed prediction
    Add
    BLAST

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 328328Probable G-protein coupled receptor 82
    PRO_0000303082Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi3 – 31N-linked (GlcNAc...) Reviewed prediction
    Glycosylationi4 – 41N-linked (GlcNAc...) Reviewed prediction

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ8BZR0.

    PTM databases

    PhosphoSiteiQ8BZR0.

    Expressioni

    Gene expression databases

    BgeeiQ8BZR0.
    CleanExiMM_GPR82.
    GenevestigatoriQ8BZR0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BZR0.
    SMRiQ8BZR0. Positions 13-327.

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG151131.
    GeneTreeiENSGT00640000091213.
    HOGENOMiHOG000112792.
    HOVERGENiHBG097852.
    InParanoidiQ8BZR0.
    KOiK08420.
    OMAiHVSMFVS.
    OrthoDBiEOG7DFXCZ.
    PhylomeDBiQ8BZR0.
    TreeFamiTF337127.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BZR0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNNSTCIQP SVISTTALPV TYIFLFIIGL FGNSLAQWVF LTKIGKKTST    50
    HIYLANLVTA NLLVCTAMPF MGIYFLRGFY WKYQSVQCRL VNFLGTLSMH 100
    VSMFVSLLIL SWIAISRYAT LMKKESKQEA TSCYERMFYG HVLKRFRQPN 150
    FARTMCIYIW GVVLVIIIPV TLYYSVVEAT EEGQSQCYNR QMELGARPSQ 200
    IAGLIGTTFI GFSFLVVVTS YYSLVSHLRR VRTCTSITEK DLTYRSVKRH 250
    LLIIQVLLVV CFLPYSIFKP IFYVLHQREG DCQQLNYLIE AKNILTCLAS 300
    ARSSTDPIIF LLLDKTFKKT LYGLLTKS 328
    Length:328
    Mass (Da):37,555
    Last modified:March 1, 2003 - v1
    Checksum:i324C3AED267FCE53
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK033761 mRNA. Translation: BAC28466.1.
    AL671117 Genomic DNA. Translation: CAM19449.1.
    BC116704 mRNA. Translation: AAI16705.1.
    AY255571 mRNA. Translation: AAO85083.1.
    CCDSiCCDS30029.1.
    RefSeqiNP_783600.1. NM_175669.3.
    XP_006527696.1. XM_006527633.1.
    UniGeneiMm.383294.

    Genome annotation databases

    EnsembliENSMUST00000053659; ENSMUSP00000062535; ENSMUSG00000047678.
    GeneIDi319200.
    KEGGimmu:319200.
    UCSCiuc009srv.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK033761 mRNA. Translation: BAC28466.1 .
    AL671117 Genomic DNA. Translation: CAM19449.1 .
    BC116704 mRNA. Translation: AAI16705.1 .
    AY255571 mRNA. Translation: AAO85083.1 .
    CCDSi CCDS30029.1.
    RefSeqi NP_783600.1. NM_175669.3.
    XP_006527696.1. XM_006527633.1.
    UniGenei Mm.383294.

    3D structure databases

    ProteinModelPortali Q8BZR0.
    SMRi Q8BZR0. Positions 13-327.
    ModBasei Search...

    Protein family/group databases

    GPCRDBi Search...

    PTM databases

    PhosphoSitei Q8BZR0.

    Proteomic databases

    PRIDEi Q8BZR0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000053659 ; ENSMUSP00000062535 ; ENSMUSG00000047678 .
    GeneIDi 319200.
    KEGGi mmu:319200.
    UCSCi uc009srv.1. mouse.

    Organism-specific databases

    CTDi 27197.
    MGIi MGI:2441734. Gpr82.

    Phylogenomic databases

    eggNOGi NOG151131.
    GeneTreei ENSGT00640000091213.
    HOGENOMi HOG000112792.
    HOVERGENi HBG097852.
    InParanoidi Q8BZR0.
    KOi K08420.
    OMAi HVSMFVS.
    OrthoDBi EOG7DFXCZ.
    PhylomeDBi Q8BZR0.
    TreeFami TF337127.

    Miscellaneous databases

    NextBioi 394366.
    PROi Q8BZR0.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8BZR0.
    CleanExi MM_GPR82.
    Genevestigatori Q8BZR0.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Epididymis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 130-233.

    Entry informationi

    Entry nameiGPR82_MOUSE
    AccessioniPrimary (citable) accession number: Q8BZR0
    Secondary accession number(s): Q80UB1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: March 1, 2003
    Last modified: July 9, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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