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Protein

Probable G-protein coupled receptor 82

Gene

Gpr82

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 82
Gene namesi
Name:Gpr82
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2441734. Gpr82.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1111ExtracellularSequence AnalysisAdd
BLAST
Transmembranei12 – 3221Helical; Name=1Sequence AnalysisAdd
BLAST
Topological domaini33 – 5523CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei56 – 7621Helical; Name=2Sequence AnalysisAdd
BLAST
Topological domaini77 – 9216ExtracellularSequence AnalysisAdd
BLAST
Transmembranei93 – 11523Helical; Name=3Sequence AnalysisAdd
BLAST
Topological domaini116 – 15641CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei157 – 17721Helical; Name=4Sequence AnalysisAdd
BLAST
Topological domaini178 – 19720ExtracellularSequence AnalysisAdd
BLAST
Transmembranei198 – 21821Helical; Name=5Sequence AnalysisAdd
BLAST
Topological domaini219 – 25133CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei252 – 27221Helical; Name=6Sequence AnalysisAdd
BLAST
Topological domaini273 – 32856ExtracellularSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 328328Probable G-protein coupled receptor 82PRO_0000303082Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi3 – 31N-linked (GlcNAc...)Sequence Analysis
Glycosylationi4 – 41N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ8BZR0.

PTM databases

PhosphoSiteiQ8BZR0.

Expressioni

Gene expression databases

BgeeiQ8BZR0.
CleanExiMM_GPR82.
GenevestigatoriQ8BZR0.

Structurei

3D structure databases

ProteinModelPortaliQ8BZR0.
SMRiQ8BZR0. Positions 13-327.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG151131.
GeneTreeiENSGT00640000091213.
HOGENOMiHOG000112792.
HOVERGENiHBG097852.
InParanoidiQ8BZR0.
KOiK08420.
OMAiTANLLVC.
OrthoDBiEOG7DFXCZ.
PhylomeDBiQ8BZR0.
TreeFamiTF337127.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BZR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNNSTCIQP SVISTTALPV TYIFLFIIGL FGNSLAQWVF LTKIGKKTST
60 70 80 90 100
HIYLANLVTA NLLVCTAMPF MGIYFLRGFY WKYQSVQCRL VNFLGTLSMH
110 120 130 140 150
VSMFVSLLIL SWIAISRYAT LMKKESKQEA TSCYERMFYG HVLKRFRQPN
160 170 180 190 200
FARTMCIYIW GVVLVIIIPV TLYYSVVEAT EEGQSQCYNR QMELGARPSQ
210 220 230 240 250
IAGLIGTTFI GFSFLVVVTS YYSLVSHLRR VRTCTSITEK DLTYRSVKRH
260 270 280 290 300
LLIIQVLLVV CFLPYSIFKP IFYVLHQREG DCQQLNYLIE AKNILTCLAS
310 320
ARSSTDPIIF LLLDKTFKKT LYGLLTKS
Length:328
Mass (Da):37,555
Last modified:February 28, 2003 - v1
Checksum:i324C3AED267FCE53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033761 mRNA. Translation: BAC28466.1.
AL671117 Genomic DNA. Translation: CAM19449.1.
BC116704 mRNA. Translation: AAI16705.1.
AY255571 mRNA. Translation: AAO85083.1.
CCDSiCCDS30029.1.
RefSeqiNP_783600.1. NM_175669.3.
UniGeneiMm.383294.

Genome annotation databases

EnsembliENSMUST00000053659; ENSMUSP00000062535; ENSMUSG00000047678.
GeneIDi319200.
KEGGimmu:319200.
UCSCiuc009srv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033761 mRNA. Translation: BAC28466.1.
AL671117 Genomic DNA. Translation: CAM19449.1.
BC116704 mRNA. Translation: AAI16705.1.
AY255571 mRNA. Translation: AAO85083.1.
CCDSiCCDS30029.1.
RefSeqiNP_783600.1. NM_175669.3.
UniGeneiMm.383294.

3D structure databases

ProteinModelPortaliQ8BZR0.
SMRiQ8BZR0. Positions 13-327.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

PTM databases

PhosphoSiteiQ8BZR0.

Proteomic databases

PRIDEiQ8BZR0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000053659; ENSMUSP00000062535; ENSMUSG00000047678.
GeneIDi319200.
KEGGimmu:319200.
UCSCiuc009srv.1. mouse.

Organism-specific databases

CTDi27197.
MGIiMGI:2441734. Gpr82.

Phylogenomic databases

eggNOGiNOG151131.
GeneTreeiENSGT00640000091213.
HOGENOMiHOG000112792.
HOVERGENiHBG097852.
InParanoidiQ8BZR0.
KOiK08420.
OMAiTANLLVC.
OrthoDBiEOG7DFXCZ.
PhylomeDBiQ8BZR0.
TreeFamiTF337127.

Miscellaneous databases

NextBioi394366.
PROiQ8BZR0.
SOURCEiSearch...

Gene expression databases

BgeeiQ8BZR0.
CleanExiMM_GPR82.
GenevestigatoriQ8BZR0.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Epididymis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 130-233.

Entry informationi

Entry nameiGPR82_MOUSE
AccessioniPrimary (citable) accession number: Q8BZR0
Secondary accession number(s): Q80UB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 10, 2007
Last sequence update: February 28, 2003
Last modified: March 31, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.