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Protein

LIM domain only protein 3

Gene

Lmo3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
LIM domain only protein 3
Short name:
LMO-3
Alternative name(s):
Neuronal-specific transcription factor DAT1
Gene namesi
Name:Lmo3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:102810. Lmo3.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000758181 – 145LIM domain only protein 3Add BLAST145

Proteomic databases

MaxQBiQ8BZL8.
PaxDbiQ8BZL8.
PRIDEiQ8BZL8.

PTM databases

PhosphoSitePlusiQ8BZL8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000030226.
CleanExiMM_LMO3.
ExpressionAtlasiQ8BZL8. baseline and differential.
GenevisibleiQ8BZL8. MM.

Interactioni

Protein-protein interaction databases

BioGridi224886. 5 interactors.
STRINGi10090.ENSMUSP00000124862.

Structurei

3D structure databases

ProteinModelPortaliQ8BZL8.
SMRiQ8BZL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 73LIM zinc-binding 1PROSITE-ProRule annotationAdd BLAST63
Domaini75 – 137LIM zinc-binding 2PROSITE-ProRule annotationAdd BLAST63

Keywords - Domaini

LIM domain, Repeat

Phylogenomic databases

eggNOGiKOG0490. Eukaryota.
ENOG410YIJ3. LUCA.
GeneTreeiENSGT00720000108603.
HOVERGENiHBG054231.
InParanoidiQ8BZL8.
PhylomeDBiQ8BZL8.
TreeFamiTF351071.

Family and domain databases

InterProiView protein in InterPro
IPR001781. Znf_LIM.
PfamiView protein in Pfam
PF00412. LIM. 2 hits.
SMARTiView protein in SMART
SM00132. LIM. 2 hits.
PROSITEiView protein in PROSITE
PS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8BZL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSVQPDTKP KGCAGCNRKI KDRYLLKALD KYWHEDCLKC ACCDCRLGEV
60 70 80 90 100
GSTLYTKANL ILCRRDYLRL FGVTGNCAAC SKLIPAFEMV MRAKDNVYHL
110 120 130 140
DCFACQLCNQ RFCVGDKFFL KNNMILCQTD YEEGLMKEGY APQVR
Length:145
Mass (Da):16,594
Last modified:March 1, 2003 - v1
Checksum:i05284546BA5EC226
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK034177 mRNA. Translation: BAC28617.1.
BC057086 mRNA. Translation: AAH57086.1.
CCDSiCCDS20669.1.
RefSeqiNP_997105.1. NM_207222.2.
XP_006505403.1. XM_006505340.1.
XP_006505404.1. XM_006505341.3.
XP_006505405.1. XM_006505342.2.
XP_006505407.1. XM_006505344.3.
XP_011239433.1. XM_011241131.2.
XP_011239434.1. XM_011241132.2.
XP_011239435.1. XM_011241133.2.
XP_017176802.1. XM_017321313.1.
UniGeneiMm.490545.

Genome annotation databases

EnsembliENSMUST00000161450; ENSMUSP00000124862; ENSMUSG00000030226.
ENSMUST00000162772; ENSMUSP00000125335; ENSMUSG00000030226.
ENSMUST00000163024; ENSMUSP00000125589; ENSMUSG00000030226.
ENSMUST00000203435; ENSMUSP00000145048; ENSMUSG00000030226.
GeneIDi109593.
KEGGimmu:109593.
UCSCiuc009enl.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiLMO3_MOUSE
AccessioniPrimary (citable) accession number: Q8BZL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2003
Last modified: July 5, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot