Dnm3

Functionⁱ

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).By similarity

Catalytic activityⁱ

GTP + H₂O = GDP + phosphate.

Regions

Feature key	Position(s)	DescriptionActions	Length
Nucleotide bindingⁱ	38 – 46	GTPBy similarity	9
Nucleotide bindingⁱ	205 – 211	GTPBy similarity	7
Nucleotide bindingⁱ	236 – 239	GTPBy similarity	4

GO - Molecular functionⁱ

GTPase activity Source: GO_Central
GTP binding Source: UniProtKB-KW
identical protein binding Source: MGI
microtubule binding Source: GO_Central
nitric-oxide synthase binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

dynamin family protein polymerization involved in mitochondrial fission Source: GO_Central
membrane fusion Source: GO_Central
mitochondrial fission Source: GO_Central
negative regulation of dendritic spine morphogenesis Source: Ensembl
positive regulation of filopodium assembly Source: Ensembl
positive regulation of synaptic vesicle recycling Source: Ensembl
postsynaptic neurotransmitter receptor internalization Source: Ensembl
synaptic vesicle budding from presynaptic endocytic zone membrane
Source: SynGO
Inferred from genetic interactionⁱ
- 21689597

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase, Motor protein
Biological process	Endocytosis
Ligand	GTP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactomeⁱ	R-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade R-MMU-2132295 MHC class II antigen presentation R-MMU-437239 Recycling pathway of L1 R-MMU-8856828 Clathrin-mediated endocytosis

Reactomeⁱ

R-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade
R-MMU-2132295 MHC class II antigen presentation
R-MMU-437239 Recycling pathway of L1
R-MMU-8856828 Clathrin-mediated endocytosis

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Dynamin-3 (EC:3.6.5.5)
Gene namesⁱ	Name:Dnm3 Synonyms:Kiaa0820
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 1

Organism-specific databases

MGIⁱ	MGI:1341299 Dnm3

Keywords - Cellular componentⁱ

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000319951	1 – 863	Dynamin-3Add BLAST		863

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	80	PhosphotyrosineBy similarity	1
Modified residueⁱ	125	Nitrated tyrosine; alternateBy similarity	1
Modified residueⁱ	125	Phosphotyrosine; alternateBy similarity	1
Modified residueⁱ	231	PhosphotyrosineBy similarity	1
Modified residueⁱ	299	N6-acetyllysineBy similarity	1
Modified residueⁱ	306	PhosphoserineBy similarity	1
Modified residueⁱ	347	PhosphoserineBy similarity	1
Modified residueⁱ	593	PhosphotyrosineBy similarity	1
Modified residueⁱ	594	N6-acetyllysineBy similarity	1
Modified residueⁱ	763	PhosphoserineBy similarity	1
Modified residueⁱ	767	PhosphoserineBy similarity	1
Modified residueⁱ	787	Omega-N-methylarginineBy similarity	1
Modified residueⁱ	847	PhosphoserineBy similarity	1

Keywords - PTMⁱ

Acetylation, Methylation, Nitration, Phosphoprotein

Proteomic databases

PaxDbⁱ	Q8BZ98
PeptideAtlas More...PeptideAtlasⁱ	Q8BZ98
PRIDEⁱ	Q8BZ98

PTM databases

iPTMnetⁱ	Q8BZ98
PhosphoSitePlusⁱ	Q8BZ98
SwissPalmⁱ	Q8BZ98

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000040265
CleanExⁱ	MM_DNM3
ExpressionAtlasⁱ	Q8BZ98 baseline and differential
Genevisibleⁱ	Q8BZ98 MM

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
Amph	Q7TQF7	2	EBI-6880033,EBI-775139

With

Entry

#Exp.

IntAct

Notes

Amph

Q7TQF7

2

EBI-6880033,EBI-775139

GO - Molecular functionⁱ

identical protein binding Source: MGI
microtubule binding Source: GO_Central
nitric-oxide synthase binding Source: Ensembl

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	222243, 1 interactor
IntActⁱ	Q8BZ98, 9 interactors
Molecular INTeraction database More...MINTⁱ	Q8BZ98
STRINGⁱ	10090.ENSMUSP00000064538

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8BZ98
SMRⁱ	Q8BZ98
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	28 – 294	Dynamin-type GPROSITE-ProRule annotationAdd BLAST	267
Domainⁱ	515 – 621	PHPROSITE-ProRule annotationAdd BLAST	107
Domainⁱ	653 – 744	GEDPROSITE-ProRule annotationAdd BLAST	92

Region

Feature key	Position(s)	DescriptionActions	Length
Regionⁱ	38 – 45	G1 motifPROSITE-ProRule annotation	8
Regionⁱ	64 – 66	G2 motifPROSITE-ProRule annotation	3
Regionⁱ	136 – 139	G3 motifPROSITE-ProRule annotation	4
Regionⁱ	205 – 208	G4 motifPROSITE-ProRule annotation	4
Regionⁱ	235 – 238	G5 motifPROSITE-ProRule annotation	4

Sequence similaritiesⁱ

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG0446 Eukaryota COG0699 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119213
HOGENOMⁱ	HOG000161069
HOVERGENⁱ	HBG107833
InParanoidⁱ	Q8BZ98
KEGG Orthology (KO) More...KOⁱ	K01528
PhylomeDBⁱ	Q8BZ98
TreeFamⁱ	TF300362

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd08771 DLP_1, 1 hit
Gene3Dⁱ	2.30.29.30, 1 hit
InterProⁱ	View protein in InterPro IPR000375 Dynamin_central IPR001401 Dynamin_GTPase IPR019762 Dynamin_GTPase_CS IPR022812 Dynamin_SF IPR030381 G_DYNAMIN_dom IPR003130 GED IPR020850 GED_dom IPR027417 P-loop_NTPase IPR011993 PH-like_dom_sf IPR001849 PH_domain
PANTHERⁱ	PTHR11566 PTHR11566, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01031 Dynamin_M, 1 hit PF00350 Dynamin_N, 1 hit PF02212 GED, 1 hit PF00169 PH, 1 hit
PRINTSⁱ	PR00195 DYNAMIN
SMARTⁱ	View protein in SMART SM00053 DYNc, 1 hit SM00302 GED, 1 hit SM00233 PH, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
PROSITEⁱ	View protein in PROSITE PS00410 G_DYNAMIN_1, 1 hit PS51718 G_DYNAMIN_2, 1 hit PS51388 GED, 1 hit PS50003 PH_DOMAIN, 1 hit

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: Q8BZ98-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGNREMEELI PLVNRLQDAF SALGQSCLLE LPQIAVVGGQ SAGKSSVLEN 
        60         70         80         90        100
FVGRDFLPRG SGIVTRRPLV LQLVTSKAEY AEFLHCKGKK FTDFDEVRHE 
       110        120        130        140        150
IEAETDRVTG MNKGISSIPI NLRVYSPHVL NLTLIDLPGI TKVPVGDQPP 
       160        170        180        190        200
DIEYQIRDMI MQFITRENCL ILAVTPANTD LANSDALKLA KEVDPQGLRT 
       210        220        230        240        250
IGVITKLDLM DEGTDARDVL ENKLLPLRRG YVGVVNRSQK DIDGKKDIKA 
       260        270        280        290        300
AMLAERKFFL SHPAYRHIAD RMGTPHLQKV LNQQLTNHIR DTLPNFRNKL 
       310        320        330        340        350
QGQLLSIEHE VEAFKNFKPE DPTRKTKALL QMVQQFAVDF EKRIEGSGDQ 
       360        370        380        390        400
VDTLELSGGA KINRIFHERF PFEIVKMEFN EKELRREISY AIKNIHGIRT 
       410        420        430        440        450
GLFTPDMAFE AIVKKQIVKL KGPSLKSVDL VMQELINTVK KCTKRLANFP 
       460        470        480        490        500
RLCEETERIV ANHIREREGK TKDQVLLLID IQVSYINTNH EDFIGFANAQ 
       510        520        530        540        550
QRSSQVHKKS TIGNQVIRKG WLTVSNIGIM KGGSKGYWFV LTAESLSWYK 
       560        570        580        590        600
DDEEKEKKYM LPLDNLKVRD VEKGFMSSKH VFALFNTEQR NVYKDYRFLE 
       610        620        630        640        650
LACDSQEDVD SWKASLLRAG VYPDKSVGSN KTENDENGQA ENFSMDPQLE 
       660        670        680        690        700
RQVETIRNLV DSYMSIINKC IRDLIPKTIM HLMINNVKDF INSELLAQLY 
       710        720        730        740        750
SSEDQNTLME ESAEQAQRRD EMLRMYQALK EALAIIGDIN TATVSTPAPP 
       760        770        780        790        800
PVDDSWLQHS RRSPPPSPTT QRRLTISAPL PRPTSGRGPA PAIPSPGPHS 
       810        820        830        840        850
GAPPVPFRPG PLPPFPNSSD SFGAPPQVPS RPTRAPPSVP SRRPPPSPTR 
       860 
PTIIRPLESS LLD

Length:863

Mass (Da):97,190

Last modified:March 1, 2003 - v1

Checksum:ⁱ8BDBB091CB10D264

GO

Isoform 2 (identifier: Q8BZ98-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
628-631: Missing.

« Hide

        10         20         30         40         50
MGNREMEELI PLVNRLQDAF SALGQSCLLE LPQIAVVGGQ SAGKSSVLEN 
        60         70         80         90        100
FVGRDFLPRG SGIVTRRPLV LQLVTSKAEY AEFLHCKGKK FTDFDEVRHE 
       110        120        130        140        150
IEAETDRVTG MNKGISSIPI NLRVYSPHVL NLTLIDLPGI TKVPVGDQPP 
       160        170        180        190        200
DIEYQIRDMI MQFITRENCL ILAVTPANTD LANSDALKLA KEVDPQGLRT 
       210        220        230        240        250
IGVITKLDLM DEGTDARDVL ENKLLPLRRG YVGVVNRSQK DIDGKKDIKA 
       260        270        280        290        300
AMLAERKFFL SHPAYRHIAD RMGTPHLQKV LNQQLTNHIR DTLPNFRNKL 
       310        320        330        340        350
QGQLLSIEHE VEAFKNFKPE DPTRKTKALL QMVQQFAVDF EKRIEGSGDQ 
       360        370        380        390        400
VDTLELSGGA KINRIFHERF PFEIVKMEFN EKELRREISY AIKNIHGIRT 
       410        420        430        440        450
GLFTPDMAFE AIVKKQIVKL KGPSLKSVDL VMQELINTVK KCTKRLANFP 
       460        470        480        490        500
RLCEETERIV ANHIREREGK TKDQVLLLID IQVSYINTNH EDFIGFANAQ 
       510        520        530        540        550
QRSSQVHKKS TIGNQVIRKG WLTVSNIGIM KGGSKGYWFV LTAESLSWYK 
       560        570        580        590        600
DDEEKEKKYM LPLDNLKVRD VEKGFMSSKH VFALFNTEQR NVYKDYRFLE 
       610        620        630        640        650
LACDSQEDVD SWKASLLRAG VYPDKSVTEN DENGQAENFS MDPQLERQVE 
       660        670        680        690        700
TIRNLVDSYM SIINKCIRDL IPKTIMHLMI NNVKDFINSE LLAQLYSSED 
       710        720        730        740        750
QNTLMEESAE QAQRRDEMLR MYQALKEALA IIGDINTATV STPAPPPVDD 
       760        770        780        790        800
SWLQHSRRSP PPSPTTQRRL TISAPLPRPT SGRGPAPAIP SPGPHSGAPP 
       810        820        830        840        850
VPFRPGPLPP FPNSSDSFGA PPQVPSRPTR APPSVPSRRP PPSPTRPTII 

RPLESSLLD

Note: No experimental confirmation available.

Show »

Length:859

Mass (Da):96,804

Checksum:ⁱ591E1B65A81A26D0

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	139	G → A in BAE28068 (PubMed:16141072).Curated		1
Sequence conflictⁱ	532 – 549	Missing in BAC65661 (PubMed:12693553).CuratedAdd BLAST		18

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_031548	628 – 631	Missing in isoform 2. 1 Publication		4

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK036199 mRNA Translation: BAC29343.1 AK049724 mRNA Translation: BAC33895.1 AK147678 mRNA Translation: BAE28068.1 BC141143 mRNA Translation: AAI41144.1 BC141144 mRNA Translation: AAI41145.1 AK122379 Transcribed RNA Translation: BAC65661.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS48417.1 [Q8BZ98-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001033708.1, NM_001038619.1 [Q8BZ98-1] NP_766234.1, NM_172646.2 [Q8BZ98-2]
UniGeneⁱ	Mm.441620 Mm.441951

Genome annotation databases

Ensemblⁱ	ENSMUST00000070330; ENSMUSP00000064538; ENSMUSG00000040265 [Q8BZ98-2]
GeneIDⁱ	103967
KEGGⁱ	mmu:103967
UCSC genome browser More...UCSCⁱ	uc007dga.2 mouse [Q8BZ98-1] uc007dgb.2 mouse [Q8BZ98-2]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
Q8BZ98	Dynamin-3		RAT		869
Dynamin 3		MONDO		1042
UPI0004D0579B		GALVR		78
UPI000B3E2C0A		NUMME		878
Uncharacterized protein (Fragment)		NEOLE		166
+526

Protein	Similar proteins		Species	Score	Length
Q8BZ98	Dynamin-2	)	HUMAN		870
DNM2 isoform 5		PANTR		870
DNM2 isoform 5		PONAB		870
Dynamin 2		GORGO		870
UPI00077D964E		PERMB		888
+1487

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK036199 mRNA Translation: BAC29343.1 AK049724 mRNA Translation: BAC33895.1 AK147678 mRNA Translation: BAE28068.1 BC141143 mRNA Translation: AAI41144.1 BC141144 mRNA Translation: AAI41145.1 AK122379 Transcribed RNA Translation: BAC65661.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS48417.1 [Q8BZ98-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001033708.1, NM_001038619.1 [Q8BZ98-1] NP_766234.1, NM_172646.2 [Q8BZ98-2]
UniGeneⁱ	Mm.441620 Mm.441951

3D structure databases

ProteinModelPortalⁱ	Q8BZ98
SMRⁱ	Q8BZ98
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	222243, 1 interactor
IntActⁱ	Q8BZ98, 9 interactors
Molecular INTeraction database More...MINTⁱ	Q8BZ98
STRINGⁱ	10090.ENSMUSP00000064538

PTM databases

iPTMnetⁱ	Q8BZ98
PhosphoSitePlusⁱ	Q8BZ98
SwissPalmⁱ	Q8BZ98

Proteomic databases

PaxDbⁱ	Q8BZ98
PeptideAtlas More...PeptideAtlasⁱ	Q8BZ98
PRIDEⁱ	Q8BZ98

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000070330; ENSMUSP00000064538; ENSMUSG00000040265 [Q8BZ98-2]
GeneIDⁱ	103967
KEGGⁱ	mmu:103967
UCSC genome browser More...UCSCⁱ	uc007dga.2 mouse [Q8BZ98-1] uc007dgb.2 mouse [Q8BZ98-2]

Organism-specific databases

CTDⁱ	26052
MGIⁱ	MGI:1341299 Dnm3
Rougeⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0446 Eukaryota COG0699 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119213
HOGENOMⁱ	HOG000161069
HOVERGENⁱ	HBG107833
InParanoidⁱ	Q8BZ98
KEGG Orthology (KO) More...KOⁱ	K01528
PhylomeDBⁱ	Q8BZ98
TreeFamⁱ	TF300362

Enzyme and pathway databases

Reactomeⁱ	R-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade R-MMU-2132295 MHC class II antigen presentation R-MMU-437239 Recycling pathway of L1 R-MMU-8856828 Clathrin-mediated endocytosis

Reactomeⁱ

R-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade
R-MMU-2132295 MHC class II antigen presentation
R-MMU-437239 Recycling pathway of L1
R-MMU-8856828 Clathrin-mediated endocytosis

Miscellaneous databases

ChiTaRSⁱ	Dnm3 mouse
Protein Ontology More...PROⁱ	PR:Q8BZ98
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000040265
CleanExⁱ	MM_DNM3
ExpressionAtlasⁱ	Q8BZ98 baseline and differential
Genevisibleⁱ	Q8BZ98 MM

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd08771 DLP_1, 1 hit
Gene3Dⁱ	2.30.29.30, 1 hit
InterProⁱ	View protein in InterPro IPR000375 Dynamin_central IPR001401 Dynamin_GTPase IPR019762 Dynamin_GTPase_CS IPR022812 Dynamin_SF IPR030381 G_DYNAMIN_dom IPR003130 GED IPR020850 GED_dom IPR027417 P-loop_NTPase IPR011993 PH-like_dom_sf IPR001849 PH_domain
PANTHERⁱ	PTHR11566 PTHR11566, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01031 Dynamin_M, 1 hit PF00350 Dynamin_N, 1 hit PF02212 GED, 1 hit PF00169 PH, 1 hit
PRINTSⁱ	PR00195 DYNAMIN
SMARTⁱ	View protein in SMART SM00053 DYNc, 1 hit SM00302 GED, 1 hit SM00233 PH, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
PROSITEⁱ	View protein in PROSITE PS00410 G_DYNAMIN_1, 1 hit PS51718 G_DYNAMIN_2, 1 hit PS51388 GED, 1 hit PS50003 PH_DOMAIN, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	DYN3_MOUSE
Accessionⁱ	Q8BZ98Primary (citable) accession number: Q8BZ98 Secondary accession number(s): B2RUH0 , Q3UGY9, Q80TR2, Q8BWW6
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
	Last sequence update:	March 1, 2003
	Last modified:	May 23, 2018
	This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

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Annotation systems

Supporting data

UniProtKB - Q8BZ98 (DYN3_MOUSE)

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Dynamin-3

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytoskeleton

Other locations

Cytoskeleton

Extracellular region or secreted

Golgi apparatus

Mitochondrion

Plasma Membrane

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ