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Q8BYB9 (PGLT1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein O-glucosyltransferase 1

EC=2.4.1.-
Alternative name(s):
CAP10-like 46 kDa protein
KTEL motif-containing protein 1
Gene names
Name:Poglut1
Synonyms:Clp46, Ktelc1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

UDP-glucosyltransferase By similarity.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Endoplasmic reticulum lumen By similarity.

Sequence similarities

Belongs to the glycosyltransferase 90 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 392369Protein O-glucosyltransferase 1
PRO_0000246686

Regions

Motif389 – 3924Prevents secretion from ER Potential

Amino acid modifications

Glycosylation531N-linked (GlcNAc...) Potential
Glycosylation2041N-linked (GlcNAc...) Potential
Glycosylation3731N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict531N → S in BAC30905. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q8BYB9 [UniParc].

Last modified July 25, 2006. Version 2.
Checksum: CAAD9133E47D3EF0

FASTA39246,379
        10         20         30         40         50         60 
MERRAGSRLR AWMLLLLLCP VQGRQKDSGS KWKVFLDQIN RALENYEPCS SQNCSCYHGV 

        70         80         90        100        110        120 
IEEDLTPFRG GISRKMMAEV VRRKLGTHYQ IIKNRLFRED DCMFPSRCSG VEHFILEVIH 

       130        140        150        160        170        180 
RLPDMEMVIN VRDYPQVPKW MEPTIPVFSF SKTSEYHDIM YPAWTFWEGG PAVWPLYPTG 

       190        200        210        220        230        240 
LGRWDLFRED LLRSAAQWPW EKKNSTAYFR GSRTSPERDP LILLSRKNPK LVDAEYTKNQ 

       250        260        270        280        290        300 
AWKSMKDTLG KPAAKDVHLI DHCKYRYLFN FRGVAASFRF KHLFLCGSLV FHVGDEWVEF 

       310        320        330        340        350        360 
FYPQLKPWVH YIPVKTDLSN VQELLQFVKA NDDIAQEIAK RGSQFIINHL QMDDITCYWE 

       370        380        390 
NLLTDYSKFL SYNVTRRKDY YQIVPRRLKT EL 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Cerebellum, Testis and Thymus.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Colon.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK031608 mRNA. Translation: BAC27475.1.
AK035948 mRNA. Translation: BAC29255.1.
AK036224 mRNA. Translation: BAC29351.1.
AK041321 mRNA. Translation: BAC30905.1.
BC026809 mRNA. Translation: AAH26809.1.
RefSeqNP_759012.1. NM_172380.3.
UniGeneMm.284366.
Mm.475345.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid230254. 1 interaction.

Protein family/group databases

CAZyGT90. Glycosyltransferase Family 90.

PTM databases

PhosphoSiteQ8BYB9.

Proteomic databases

PaxDbQ8BYB9.
PRIDEQ8BYB9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000036210; ENSMUSP00000038166; ENSMUSG00000034064.
GeneID224143.
KEGGmmu:224143.
UCSCuc007zfc.1. mouse.

Organism-specific databases

CTD56983.
MGIMGI:2444232. Poglut1.

Phylogenomic databases

eggNOGNOG248922.
GeneTreeENSGT00530000063132.
HOVERGENHBG069044.
InParanoidQ8BYB9.
KOK13667.
OMAWGATEIT.
OrthoDBEOG7R831J.
PhylomeDBQ8BYB9.
TreeFamTF323280.

Enzyme and pathway databases

ReactomeREACT_188257. Signal Transduction.
UniPathwayUPA00378.

Gene expression databases

ArrayExpressQ8BYB9.
BgeeQ8BYB9.
CleanExMM_KTELC1.
GenevestigatorQ8BYB9.

Family and domain databases

InterProIPR006598. LipoPS_modifying.
[Graphical view]
PfamPF05686. Glyco_transf_90. 1 hit.
[Graphical view]
SMARTSM00672. CAP10. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPOGLUT1. mouse.
NextBio377117.
PROQ8BYB9.
SOURCESearch...

Entry information

Entry namePGLT1_MOUSE
AccessionPrimary (citable) accession number: Q8BYB9
Secondary accession number(s): Q8R0H7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 25, 2006
Last modified: April 16, 2014
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot