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Protein
Submitted name:

Putative uncharacterized protein

Gene

Mthfd1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Mthfd1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1342005. Mthfd1.

PTM / Processingi

Proteomic databases

PaxDbiQ8BY49.
PeptideAtlasiQ8BY49.

Expressioni

Gene expression databases

BgeeiENSMUSG00000021048.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021443.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 125THF_DHG_CYHInterPro annotationAdd BLAST120
Domaini129 – 241THF_DHG_CYH_CInterPro annotationAdd BLAST113

Phylogenomic databases

eggNOGiKOG4230. Eukaryota.
COG0190. LUCA.
COG2759. LUCA.
HOVERGENiHBG006411.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01576. THF_DHG_CYH. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000672. THF_DH/CycHdrlase.
IPR020630. THF_DH/CycHdrlase_cat_dom.
IPR020867. THF_DH/CycHdrlase_CS.
IPR020631. THF_DH/CycHdrlase_NAD-bd_dom.
[Graphical view]
PfamiPF00763. THF_DHG_CYH. 1 hit.
PF02882. THF_DHG_CYH_C. 1 hit.
[Graphical view]
PRINTSiPR00085. THFDHDRGNASE.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00766. THF_DHG_CYH_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8BY49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPAGILNGK LVSAQIRDRL KNQVTRMQEQ VPGFTPGLAI LQVGDRDDSN
60 70 80 90 100
LYINVKLKAA EEIGIKATHI KLPRTSTESE VLKYVISLNE DASVHGFIVQ
110 120 130 140 150
LPLDSENSIN TEAVINAIAP EKDVDGLTSV SAGKLARGDL NDCFIPCTPK
160 170 180 190 200
GCLELIKEAG VQIAGRHAVV VGRSKIVGAP MHDLLLWNNA TVTTCHSKTA
210 220 230 240
NLDKEVNKGD ILVVATGQPE MVKGEWIKPG AVVIDCGINY VPDDTKP
Length:247
Mass (Da):26,463
Last modified:October 11, 2005 - v2
Checksum:i0F98C6FA54DD4875
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei247Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK042019 mRNA. Translation: BAC31133.2.
UniGeneiMm.29584.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK042019 mRNA. Translation: BAC31133.2.
UniGeneiMm.29584.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021443.

Proteomic databases

PaxDbiQ8BY49.
PeptideAtlasiQ8BY49.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1342005. Mthfd1.

Phylogenomic databases

eggNOGiKOG4230. Eukaryota.
COG0190. LUCA.
COG2759. LUCA.
HOVERGENiHBG006411.

Miscellaneous databases

ChiTaRSiMthfd1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021048.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01576. THF_DHG_CYH. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000672. THF_DH/CycHdrlase.
IPR020630. THF_DH/CycHdrlase_cat_dom.
IPR020867. THF_DH/CycHdrlase_CS.
IPR020631. THF_DH/CycHdrlase_NAD-bd_dom.
[Graphical view]
PfamiPF00763. THF_DHG_CYH. 1 hit.
PF02882. THF_DHG_CYH_C. 1 hit.
[Graphical view]
PRINTSiPR00085. THFDHDRGNASE.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00766. THF_DHG_CYH_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BY49_MOUSE
AccessioniPrimary (citable) accession number: Q8BY49
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.