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Protein

Centrosomal protein of 95 kDa

Gene

Cep95

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Centrosomal protein of 95 kDa
Short name:
Cep95
Alternative name(s):
Coiled-coil domain-containing protein 45
Gene namesi
Name:Cep95
Synonyms:Ccdc45
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2443502. Cep95.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002345061 – 827Centrosomal protein of 95 kDaAdd BLAST827

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei447PhosphoserineCombined sources1
Modified residuei449PhosphoserineBy similarity1
Modified residuei451PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8BVV7.
PaxDbiQ8BVV7.
PRIDEiQ8BVV7.

PTM databases

iPTMnetiQ8BVV7.
PhosphoSitePlusiQ8BVV7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000018372.
CleanExiMM_CCDC45.
ExpressionAtlasiQ8BVV7. baseline and differential.
GenevisibleiQ8BVV7. MM.

Structurei

3D structure databases

ProteinModelPortaliQ8BVV7.
SMRiQ8BVV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili584 – 633Sequence analysisAdd BLAST50
Coiled coili701 – 795Sequence analysisAdd BLAST95

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi506 – 513Poly-Glu8

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IHYF. Eukaryota.
ENOG4110YN5. LUCA.
GeneTreeiENSGT00390000005412.
HOGENOMiHOG000231030.
HOVERGENiHBG056170.
InParanoidiQ8BVV7.
KOiK16544.
OMAiRAPCPIG.
OrthoDBiEOG091G0MMH.
TreeFamiTF333224.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
InterProiView protein in InterPro
IPR026619. CEP95.
IPR001715. CH-domain.
PANTHERiPTHR22545. PTHR22545. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8BVV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSEAEWVT IANNLLFKCH IHLRIHELQD CDANVFIALY QSILGEKVPD
60 70 80 90 100
LIVLPRNQED EAHNVQAVID SLALDYLQVS LSHITGENIV KGDNESIRNL
110 120 130 140 150
LEIFDGLLDY LTEHISESSP NKSETEQYSK DSHGEEAGED LERTEEAKWR
160 170 180 190 200
NASFMRCSFS SDTLGPTWDE DEAESTGEII RLGDTAHTFS QRSNGAQNSK
210 220 230 240 250
DLRSRKASAS PGVEPPEEML NPGPLGFLSQ NGPPCEAASE TPPMSMVPSA
260 270 280 290 300
RKLGEPIRAA IPLHPPYHPS EPRAPCPIGK EYLWSSRYLS TPTSGEHMAP
310 320 330 340 350
SVEPDDAFLT STLFKDDDQE TYLPKPEATR TRKPSKGERD ENRAAIPSEH
360 370 380 390 400
LPFSQKARKP LTEQELHAMS EKLSQRLSEL DWMLKTALGD RGTGETDGND
410 420 430 440 450
GDGGGEEVRS GNEEMLSQHS DSVMEYGPKK PRPGFSTCRK APYRSHSLSP
460 470 480 490 500
SSVNKHRQLE KEKKRQHKSK GTDSCHFQAK ALTEAFEREL RKHKVQENVG
510 520 530 540 550
LRGIREEEEE EEETGKSYRE VVPKGTSKRS QVQKTYSRKT AAPSPKGDGR
560 570 580 590 600
LKSSKASPMK VSEHSLLSLM LEQFPFLYVS DPTLTKMWKQ QMAQVEQLKR
610 620 630 640 650
EAQRENRSKK KLQDEIEEAL RRHDLLTALV KKEYDHNKRL QDFRDRIQRQ
660 670 680 690 700
RLTQSKIKEN RHQSVRARKY YDDYRVQLRA KMMKMRTREE MIFKKLFEEG
710 720 730 740 750
LQIQKQRLRD LRNYAKEKRN EEKRQHQNEL DSMENHYKDQ FSLLAEAISQ
760 770 780 790 800
ERQELKVRQK FQAQTLHKVK RELRAKMEKE IQQLQHMITQ NDDDAFFREL
810 820
EAERFKARLQ LASFQYSKNP FPRGQTS
Length:827
Mass (Da):95,210
Last modified:June 28, 2011 - v2
Checksum:i8E512C718DCED49B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti412N → D in BAC36324 (PubMed:16141072).Curated1
Sequence conflicti456H → N in BAC36324 (PubMed:16141072).Curated1
Sequence conflicti663Q → P in BAC36324 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK076400 mRNA. Translation: BAC36324.1.
AL593847, AL603664 Genomic DNA. Translation: CAM16225.1.
AL603664, AL593847 Genomic DNA. Translation: CAM18572.1.
CH466558 Genomic DNA. Translation: EDL34315.1.
CCDSiCCDS25563.1.
RefSeqiNP_796062.2. NM_177088.3.
UniGeneiMm.30524.
Mm.441582.

Genome annotation databases

EnsembliENSMUST00000018516; ENSMUSP00000018516; ENSMUSG00000018372.
GeneIDi320162.
KEGGimmu:320162.
UCSCiuc007lzu.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiCEP95_MOUSE
AccessioniPrimary (citable) accession number: Q8BVV7
Secondary accession number(s): A2A5Z8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: June 28, 2011
Last modified: June 7, 2017
This is version 96 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot