ID   STX16_MOUSE             Reviewed;         326 AA.
AC   Q8BVI5;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 2.
DT   13-OCT-2009, entry version 50.
DE   RecName: Full=Syntaxin-16;
GN   Name=Stx16;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Medulla oblongata;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
RA   Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
RA   Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
RA   Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
RA   Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
RA   Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
RA   di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
RA   Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
RA   Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
RA   Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
RA   Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
RA   Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
RA   Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
RA   Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
RA   Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
RA   Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
RA   Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
RA   Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
RA   Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
RA   Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
RA   Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
RA   Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
RA   Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
RA   Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
RA   Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
RA   Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
RA   Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
RA   Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
RA   Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
RA   Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
RA   Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
RA   Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=Brain cortex;
RX   PubMed=17114649; DOI=10.1074/mcp.M600046-MCP200;
RA   Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,
RA   Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,
RA   Gerrits B., Panse C., Schlapbach R., Mansuy I.M.;
RT   "Qualitative and quantitative analyses of protein phosphorylation in
RT   naive and stimulated mouse synaptosomal preparations.";
RL   Mol. Cell. Proteomics 6:283-293(2007).
CC   -!- FUNCTION: SNARE involved in a vesicular transport step within the
CC       Golgi stack (By similarity).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type
CC       IV membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the syntaxin family.
CC   -!- SIMILARITY: Contains 1 t-SNARE coiled-coil homology domain.
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DR   EMBL; AK078110; BAC37129.1; ALT_INIT; mRNA.
DR   IPI; IPI00621076; -.
DR   UniGene; Mm.277977; -.
DR   HSSP; P32851; 1JTH.
DR   STRING; Q8BVI5; -.
DR   PhosphoSite; Q8BVI5; -.
DR   PRIDE; Q8BVI5; -.
DR   Ensembl; ENSMUST00000094281; ENSMUSP00000091836; ENSMUSG00000027522; Mus musculus.
DR   UCSC; uc008oel.1; mouse.
DR   MGI; MGI:1923396; Stx16.
DR   HOGENOM; Q8BVI5; -.
DR   HOVERGEN; Q8BVI5; -.
DR   ArrayExpress; Q8BVI5; -.
DR   Bgee; Q8BVI5; -.
DR   CleanEx; MM_STX16; -.
DR   Genevestigator; Q8BVI5; -.
DR   GermOnline; ENSMUSG00000027522; Mus musculus.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR   InterPro; IPR006011; Syntaxin_N.
DR   InterPro; IPR000727; T_SNARE.
DR   Pfam; PF05739; SNARE; 1.
DR   Pfam; PF00804; Syntaxin; 1.
DR   SMART; SM00397; t_SNARE; 1.
DR   PROSITE; PS00914; SYNTAXIN; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Golgi apparatus; Membrane; Phosphoprotein;
KW   Protein transport; Transmembrane; Transport.
FT   CHAIN         1    326       Syntaxin-16.
FT                                /FTId=PRO_0000210227.
FT   TOPO_DOM      1    302       Cytoplasmic (Potential).
FT   TRANSMEM    303    323       Anchor for type IV membrane protein
FT                                (Potential).
FT   TOPO_DOM    324    326       Vesicular (Potential).
FT   DOMAIN      231    293       t-SNARE coiled-coil homology.
FT   MOD_RES      35     35       Phosphoserine.
FT   CONFLICT      1      1       M -> T (in Ref. 1; BAC37129).
SQ   SEQUENCE   326 AA;  37052 MW;  12992627BB4D385D CRC64;
     MATRRLTDAF LLLRNNSIQT RQLLAEQVSS HTTSSPLHSR SIAADVDELA DDRMALVSGI
     SLDPEAAIGV TKRSPPKWVD GVDEIQYDVG RIKQKMKELA SLHDKHLNRP TLDDSSEEEH
     AIEITTQEVT QLFHRCQRAV QALPSRARRA CSEQEERLLR NVVASLAQAL QELSTSFRHA
     QSDYLKRMKN REERSQHFFD TPVPLMDDGD DATLYGQGFT DDQLVLVEQN TLMVEERERE
     IRQIVQSISD LNEIFRDLGA MIVEQGTVLD RIDYNVEQSC VKTEDGLKQL HKAEQYQKKN
     RKMLVIVILV AVIIVLLVAL VAVKSR
//