SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8BVE8

- NSD2_MOUSE

UniProt

Q8BVE8 - NSD2_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Histone-lysine N-methyltransferase NSD2
Gene
Whsc1, Kiaa1090, Nsd2
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Histone methyltransferase with histone H3 'Lys-27' (H3K27me) methyltransferase activity.1 Publication

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi453 – 52169HMG box
Add
BLAST
Zinc fingeri667 – 71347PHD-type 1
Add
BLAST
Zinc fingeri714 – 77057PHD-type 2
Add
BLAST
Zinc fingeri831 – 87545PHD-type 3
Add
BLAST
Zinc fingeri1239 – 128648PHD-type 4; atypical
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. chromatin binding Source: MGI
  3. histone-lysine N-methyltransferase activity Source: MGI
  4. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. atrial septum primum morphogenesis Source: MGI
  2. atrial septum secundum morphogenesis Source: MGI
  3. bone development Source: MGI
  4. chromatin modification Source: MGI
  5. histone lysine methylation Source: GOC
  6. membranous septum morphogenesis Source: MGI
  7. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  8. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Methyltransferase, Transferase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, S-adenosyl-L-methionine, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferase NSD2 (EC:2.1.1.43)
Alternative name(s):
Multiple myeloma SET domain-containing protein
Short name:
MMSET
Nuclear SET domain-containing protein 2
Short name:
NSD2
Wolf-Hirschhorn syndrome candidate 1 protein homolog
Short name:
WHSC1
Gene namesi
Name:Whsc1
Synonyms:Kiaa1090, Nsd2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 5

Organism-specific databases

MGIiMGI:1276574. Whsc1.

Subcellular locationi

Nucleus By similarity. Chromosome By similarity

GO - Cellular componenti

  1. chromosome Source: UniProtKB-SubCell
  2. nuclear membrane Source: Ensembl
  3. nucleolus Source: Ensembl
  4. nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi1138 – 11381R → A: No methyltransferase activity. 1 Publication
Mutagenesisi1144 – 11441C → A: No methyltransferase activity. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13651365Histone-lysine N-methyltransferase NSD2
PRO_0000259520Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei110 – 1101Phosphothreonine By similarity
Modified residuei114 – 1141Phosphothreonine By similarity
Modified residuei121 – 1211Phosphoserine By similarity
Modified residuei376 – 3761Phosphoserine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8BVE8.
PaxDbiQ8BVE8.
PRIDEiQ8BVE8.

PTM databases

PhosphoSiteiQ8BVE8.

Expressioni

Tissue specificityi

Expressed preferentially in rapidly growing embryonic tissues.1 Publication

Developmental stagei

Ubiquitously expressed in early development.1 Publication

Gene expression databases

ArrayExpressiQ8BVE8.
BgeeiQ8BVE8.
CleanExiMM_WHSC1.
GenevestigatoriQ8BVE8.

Interactioni

Protein-protein interaction databases

BioGridi223605. 13 interactions.
DIPiDIP-60452N.
IntActiQ8BVE8. 3 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ8BVE8.
SMRiQ8BVE8. Positions 217-285, 667-712, 716-763, 833-873, 877-973, 976-1203, 1239-1327.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini222 – 28665PWWP 1
Add
BLAST
Domaini880 – 94263PWWP 2
Add
BLAST
Domaini1011 – 106151AWS
Add
BLAST
Domaini1063 – 1180118SET
Add
BLAST
Domaini1187 – 120317Post-SET
Add
BLAST

Sequence similaritiesi

Contains 1 AWS domain.
Contains 1 post-SET domain.
Contains 2 PWWP domains.
Contains 1 SET domain.

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG2940.
GeneTreeiENSGT00740000114921.
HOGENOMiHOG000230893.
HOVERGENiHBG079979.
KOiK11424.
OMAiPSKGKMM.
OrthoDBiEOG7Z69BG.
PhylomeDBiQ8BVE8.
TreeFamiTF329088.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
3.30.40.10. 3 hits.
InterProiIPR006560. AWS.
IPR009071. HMG_box_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00505. HMG_box. 1 hit.
PF00628. PHD. 1 hit.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00398. HMG. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 2 hits.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
SSF57903. SSF57903. 3 hits.
PROSITEiPS51215. AWS. 1 hit.
PS50118. HMG_BOX_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8BVE8-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MEFSIRKSPL SVQKVVKCMK MKQTPEILGS ANGKTQNCEV NHECSVFLSK     50
AQLSNSLQEG VMQKFNGHDA LPFLPAEKLK DLTSCVFNGE PGAHDTKLCF 100
EAQEVKGIGT PPNTTPIKNG SPEIKLKITK TYMNGKPLFE SSICGDGAAD 150
VSQSEENEQK SDNKTRRNRK RSIKYDSLLE QGLVEAALVS KISSPADKKI 200
PVKKESCPNT GRDRDLLLKY NVGDLVWSKV SGYPWWPCMV SADPLLHNHT 250
KLKGQKKSAR QYHVQFFGDA PERAWIFEKS LVAFEGEEQF EKLCQESAKQ 300
APTKAEKIKL LKPISGRLRA QWEMGIVQAE EAASMSIEER KAKFTFLYVG 350
DQLHLNPQVA KEAGIVTEPL GEMVDSSGAS EEAAVDPGSV REEDIPTKRR 400
RRTKRSSSAE NQEGDPGTDK STPPKMAEAE PKRGVGSPAG RKKSTGSAPR 450
SRKGDSAAQF LVFCQKHRDE VVAEHPDASG EEIEELLGSQ WSMLNEKQKA 500
RYNTKFSLMI SAQSEEDSGN GNGKKRSHTK RADDPAEDVD VEDAPRKRLR 550
ADKHSLRKRE TITDKTARTS SYKAIEAASS LKSQAATKNL SDACKPLKKR 600
NRASATASSA LGFNKSSSPS ASLTEHEVSD SPGDEPSESP YESADETQTE 650
ASVSSKKSER GMAAKKEYVC QLCEKTGSLL LCEGPCCGAF HLACLGLSRR 700
PEGRFTCTEC ASGIHSCFVC KESKMEVKRC VVNQCGKFYH EACVKKYPLT 750
VFESRGFRCP LHSCMSCHAS NPSNPRPSKG KMMRCVRCPV AYHGGDACLA 800
AGCSVIASNS IICTGHFTAR KGKRHHTHVN VSWCFVCSKG GSLLCCEACP 850
AAFHPDCLNI EMPDGSWFCN DCRAGKKLHF QDIIWVKLGN YRWWPAEVCH 900
PKNVPPNIQK MKHEIGEFPV FFFGSKDYYW THQARVFPYM EGDRGSRYQG 950
VRGIGRVFKN ALQEAEARFN EVKLQREARE TQESERKPPP YKHIKVNKPY 1000
GKVQIYTADI SEIPKCNCKP TDENPCGSDS ECLNRMLMFE CHPQVCPAGE 1050
YCQNQCFTKR QYPETKIIKT DGKGWGLVAK RDIRKGEFVN EYVGELIDEE 1100
ECMARIKYAH ENDITHFYML TIDKDRIIDA GPKGNYSRFM NHSCQPNCET 1150
LKWTVNGDTR VGLFAVCDIP AGTELTFNYN LDCLGNEKTV CRCGASNCSG 1200
FLGDRPKTSA SLSSEEKGKK AKKKTRRRRA KGEGKRQSED ECFRCGDGGQ 1250
LVLCDRKFCT KAYHLSCLGL GKRPFGKWEC PWHHCDVCGK PSTSFCHLCP 1300
NSFCKEHQDG TAFRSTQDGQ SYCCEHDLRA DSSSSTKTEK PFPESLKSKG 1350
KRKKRRCWRR VTDGK 1365
Length:1,365
Mass (Da):152,253
Last modified:October 31, 2006 - v2
Checksum:iD8DC3F687D3EA2C2
GO
Isoform 2 (identifier: Q8BVE8-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     558-558: K → KQ

Show »
Length:1,366
Mass (Da):152,381
Checksum:i28858A53E6156DEF
GO
Isoform 3 (identifier: Q8BVE8-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-519: Missing.
     520-522: NGN → MGM
     558-558: K → KQ

Note: No experimental confirmation available.

Show »
Length:847
Mass (Da):95,042
Checksum:iEE0EF9742565F18D
GO
Isoform RE-IIBP (identifier: Q8BVE8-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-661: Missing.

Show »
Length:704
Mass (Da):79,633
Checksum:iDFB1AC7E5D1E7E4F
GO

Sequence cautioni

The sequence ACE75882.1 differs from that shown. Reason: Incorrectly indicated as originating from human.
The sequence BAC37342.1 differs from that shown. Reason: Frameshift at positions 649 and 759.
The sequence BAC98097.1 differs from that shown. Reason: Erroneous initiation.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 661661Missing in isoform RE-IIBP.
VSP_044420Add
BLAST
Alternative sequencei1 – 519519Missing in isoform 3.
VSP_021424Add
BLAST
Alternative sequencei520 – 5223NGN → MGM in isoform 3.
VSP_021425
Alternative sequencei558 – 5581K → KQ in isoform 2 and isoform 3.
VSP_021426

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti757 – 7571F → L in BAC37342. 1 Publication
Sequence conflicti1019 – 10191K → T in ACE75882. 1 Publication
Sequence conflicti1345 – 13451S → L in AAH53454. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU733655 mRNA. Translation: ACE75882.1. Sequence problems.
AK129287 mRNA. Translation: BAC98097.1. Different initiation.
AC163329 Genomic DNA. No translation available.
AK078622 mRNA. Translation: BAC37342.1. Frameshift.
BC046473 mRNA. Translation: AAH46473.1.
BC053454 mRNA. Translation: AAH53454.1.
CCDSiCCDS51467.1. [Q8BVE8-2]
CCDS51468.1. [Q8BVE8-1]
RefSeqiNP_001074571.2. NM_001081102.2. [Q8BVE8-2]
NP_780440.2. NM_175231.2. [Q8BVE8-1]
XP_006503721.1. XM_006503658.1. [Q8BVE8-2]
XP_006503722.1. XM_006503659.1. [Q8BVE8-2]
XP_006503723.1. XM_006503660.1. [Q8BVE8-1]
UniGeneiMm.19892.
Mm.332320.
Mm.491382.

Genome annotation databases

EnsembliENSMUST00000058096; ENSMUSP00000058940; ENSMUSG00000057406. [Q8BVE8-1]
ENSMUST00000066854; ENSMUSP00000067205; ENSMUSG00000057406. [Q8BVE8-2]
ENSMUST00000075812; ENSMUSP00000075210; ENSMUSG00000057406. [Q8BVE8-2]
GeneIDi107823.
KEGGimmu:107823.
UCSCiuc008xbm.2. mouse. [Q8BVE8-1]
uc012duw.1. mouse. [Q8BVE8-2]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU733655 mRNA. Translation: ACE75882.1 . Sequence problems.
AK129287 mRNA. Translation: BAC98097.1 . Different initiation.
AC163329 Genomic DNA. No translation available.
AK078622 mRNA. Translation: BAC37342.1 . Frameshift.
BC046473 mRNA. Translation: AAH46473.1 .
BC053454 mRNA. Translation: AAH53454.1 .
CCDSi CCDS51467.1. [Q8BVE8-2 ]
CCDS51468.1. [Q8BVE8-1 ]
RefSeqi NP_001074571.2. NM_001081102.2. [Q8BVE8-2 ]
NP_780440.2. NM_175231.2. [Q8BVE8-1 ]
XP_006503721.1. XM_006503658.1. [Q8BVE8-2 ]
XP_006503722.1. XM_006503659.1. [Q8BVE8-2 ]
XP_006503723.1. XM_006503660.1. [Q8BVE8-1 ]
UniGenei Mm.19892.
Mm.332320.
Mm.491382.

3D structure databases

ProteinModelPortali Q8BVE8.
SMRi Q8BVE8. Positions 217-285, 667-712, 716-763, 833-873, 877-973, 976-1203, 1239-1327.
ModBasei Search...

Protein-protein interaction databases

BioGridi 223605. 13 interactions.
DIPi DIP-60452N.
IntActi Q8BVE8. 3 interactions.

PTM databases

PhosphoSitei Q8BVE8.

Proteomic databases

MaxQBi Q8BVE8.
PaxDbi Q8BVE8.
PRIDEi Q8BVE8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000058096 ; ENSMUSP00000058940 ; ENSMUSG00000057406 . [Q8BVE8-1 ]
ENSMUST00000066854 ; ENSMUSP00000067205 ; ENSMUSG00000057406 . [Q8BVE8-2 ]
ENSMUST00000075812 ; ENSMUSP00000075210 ; ENSMUSG00000057406 . [Q8BVE8-2 ]
GeneIDi 107823.
KEGGi mmu:107823.
UCSCi uc008xbm.2. mouse. [Q8BVE8-1 ]
uc012duw.1. mouse. [Q8BVE8-2 ]

Organism-specific databases

CTDi 7468.
MGIi MGI:1276574. Whsc1.
Rougei Search...

Phylogenomic databases

eggNOGi COG2940.
GeneTreei ENSGT00740000114921.
HOGENOMi HOG000230893.
HOVERGENi HBG079979.
KOi K11424.
OMAi PSKGKMM.
OrthoDBi EOG7Z69BG.
PhylomeDBi Q8BVE8.
TreeFami TF329088.

Miscellaneous databases

ChiTaRSi WHSC1. human.
NextBioi 35470773.
PROi Q8BVE8.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q8BVE8.
Bgeei Q8BVE8.
CleanExi MM_WHSC1.
Genevestigatori Q8BVE8.

Family and domain databases

Gene3Di 1.10.30.10. 1 hit.
3.30.40.10. 3 hits.
InterProi IPR006560. AWS.
IPR009071. HMG_box_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF00505. HMG_box. 1 hit.
PF00628. PHD. 1 hit.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00570. AWS. 1 hit.
SM00398. HMG. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 2 hits.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF47095. SSF47095. 1 hit.
SSF57903. SSF57903. 3 hits.
PROSITEi PS51215. AWS. 1 hit.
PS50118. HMG_BOX_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity."
    Kim J.Y., Kee H.J., Choe N.W., Kim S.M., Eom G.H., Baek H.J., Kook H., Kook H., Seo S.B.
    Mol. Cell. Biol. 28:2023-2034(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM RE-IIBP), FUNCTION, CATALYTIC ACTIVITY, MUTAGENESIS OF ARG-1138 AND CYS-1144.
  2. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
    DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Embryonic tail.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 446-1365 (ISOFORM 1).
    Strain: C57BL/6J.
    Tissue: Adrenal gland.
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 516-1365 (ISOFORM 2).
    Strain: FVB/N.
    Tissue: Limb and Mammary tumor.
  6. "WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma."
    Stec I., Wright T.J., van Ommen G.-J.B., de Boer P.A., van Haeringen A., Moorman A.F.M., Altherr M.R., den Dunnen J.T.
    Hum. Mol. Genet. 7:1071-1082(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.

Entry informationi

Entry nameiNSD2_MOUSE
AccessioniPrimary (citable) accession number: Q8BVE8
Secondary accession number(s): B3VCH6
, Q6ZPY1, Q7TSF5, Q811F0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: July 9, 2014
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi