Reviewed, UniProtKB/Swiss-Prot Q8BVE8 (NSD2_MOUSE)

Names and origin

Protein names

Recommended name:
    Probable histone-lysine N-methyltransferase NSD2
    EC=2.1.1.43
Alternative name(s):
    Nuclear SET domain-containing protein 2
    Wolf-Hirschhorn syndrome candidate 1 protein homolog

Gene names

Name:	Whsc1
Synonyms:	Kiaa1090, Nsd2

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	1365 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Probable histone methyltransferase By similarity.
Catalytic activity	S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.
Subcellular location	Nucleus By similarity.
Tissue specificity	Expressed preferentially in rapidly growing embryonic tissues. Ref.5
Developmental stage	Ubiquitously expressed in early development. Ref.5
Sequence similarities	Belongs to the histone-lysine methyltransferase family. SET2 subfamily. Contains 1 AWS domain. Contains 1 HMG box DNA-binding domain. Contains 4 PHD-type zinc fingers. Contains 1 post-SET domain. Contains 2 PWWP domains. Contains 1 SET domain.
Sequence caution	The sequence BAC37342.1 differs from that shown. Reason: Frameshift at positions 649 and 759.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Repeat Zinc-finger
Ligand	DNA-binding Metal-binding Zinc
Molecular function	Chromatin regulator Methyltransferase Transferase
PTM	Acetylation Phosphoprotein
Gene Ontology (GO)
Biological process	chromatin modification Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription Inferred from electronic annotation. Source: UniProtKB-KW transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: EC protein binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8BVE8-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8BVE8-2)

The sequence of this isoform differs from the canonical sequence as follows:
     558-558: K → KQ

Isoform 3 (identifier: Q8BVE8-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-519: Missing.
     520-522: NGN → MGM
     558-558: K → KQ

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1365	1365	Probable histone-lysine N-methyltransferase NSD2		PRO_0000259520
Regions
	Domain	222 – 286	65	PWWP 1
	Domain	880 – 942	63	PWWP 2
	Domain	1011 – 1061	51	AWS
	Domain	1062 – 1184	123	SET
	Domain	1187 – 1203	17	Post-SET
	DNA binding	453 – 521	69	HMG box
	Zinc finger	667 – 713	47	PHD-type 1
	Zinc finger	714 – 770	57	PHD-type 2
	Zinc finger	831 – 875	45	PHD-type 3
	Zinc finger	1239 – 1286	48	PHD-type 4; atypical
Amino acid modifications
	Modified residue	110	1	Phosphothreonine By similarity
	Modified residue	115	1	Phosphothreonine By similarity
	Modified residue	121	1	Phosphoserine By similarity
	Modified residue	437	1	Phosphoserine By similarity
	Modified residue	779	1	N6-acetyllysine By similarity
	Modified residue	781	1	N6-acetyllysine By similarity
Natural variations
	Alternative sequence	1 – 519	519	Missing in isoform 3.		VSP_021424
	Alternative sequence	520 – 522	3	NGN → MGM in isoform 3.		VSP_021425
	Alternative sequence	558	1	K → KQ in isoform 2 and isoform 3.		VSP_021426
Experimental info
	Sequence conflict	757	1	F → L in BAC37342. Ref.3
	Sequence conflict	1345	1	S → L in AAH53454. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified October 31, 2006. Version 2. Checksum: D8DC3F687D3EA2C2	FASTA	1,365	152,253
	10 20 30 40 50 60 MEFSIRKSPL SVQKVVKCMK MKQTPEILGS ANGKTQNCEV NHECSVFLSK AQLSNSLQEG 70 80 90 100 110 120 VMQKFNGHDA LPFLPAEKLK DLTSCVFNGE PGAHDTKLCF EAQEVKGIGT PPNTTPIKNG 130 140 150 160 170 180 SPEIKLKITK TYMNGKPLFE SSICGDGAAD VSQSEENEQK SDNKTRRNRK RSIKYDSLLE 190 200 210 220 230 240 QGLVEAALVS KISSPADKKI PVKKESCPNT GRDRDLLLKY NVGDLVWSKV SGYPWWPCMV 250 260 270 280 290 300 SADPLLHNHT KLKGQKKSAR QYHVQFFGDA PERAWIFEKS LVAFEGEEQF EKLCQESAKQ 310 320 330 340 350 360 APTKAEKIKL LKPISGRLRA QWEMGIVQAE EAASMSIEER KAKFTFLYVG DQLHLNPQVA 370 380 390 400 410 420 KEAGIVTEPL GEMVDSSGAS EEAAVDPGSV REEDIPTKRR RRTKRSSSAE NQEGDPGTDK 430 440 450 460 470 480 STPPKMAEAE PKRGVGSPAG RKKSTGSAPR SRKGDSAAQF LVFCQKHRDE VVAEHPDASG 490 500 510 520 530 540 EEIEELLGSQ WSMLNEKQKA RYNTKFSLMI SAQSEEDSGN GNGKKRSHTK RADDPAEDVD 550 560 570 580 590 600 VEDAPRKRLR ADKHSLRKRE TITDKTARTS SYKAIEAASS LKSQAATKNL SDACKPLKKR 610 620 630 640 650 660 NRASATASSA LGFNKSSSPS ASLTEHEVSD SPGDEPSESP YESADETQTE ASVSSKKSER 670 680 690 700 710 720 GMAAKKEYVC QLCEKTGSLL LCEGPCCGAF HLACLGLSRR PEGRFTCTEC ASGIHSCFVC 730 740 750 760 770 780 KESKMEVKRC VVNQCGKFYH EACVKKYPLT VFESRGFRCP LHSCMSCHAS NPSNPRPSKG 790 800 810 820 830 840 KMMRCVRCPV AYHGGDACLA AGCSVIASNS IICTGHFTAR KGKRHHTHVN VSWCFVCSKG 850 860 870 880 890 900 GSLLCCEACP AAFHPDCLNI EMPDGSWFCN DCRAGKKLHF QDIIWVKLGN YRWWPAEVCH 910 920 930 940 950 960 PKNVPPNIQK MKHEIGEFPV FFFGSKDYYW THQARVFPYM EGDRGSRYQG VRGIGRVFKN 970 980 990 1000 1010 1020 ALQEAEARFN EVKLQREARE TQESERKPPP YKHIKVNKPY GKVQIYTADI SEIPKCNCKP 1030 1040 1050 1060 1070 1080 TDENPCGSDS ECLNRMLMFE CHPQVCPAGE YCQNQCFTKR QYPETKIIKT DGKGWGLVAK 1090 1100 1110 1120 1130 1140 RDIRKGEFVN EYVGELIDEE ECMARIKYAH ENDITHFYML TIDKDRIIDA GPKGNYSRFM 1150 1160 1170 1180 1190 1200 NHSCQPNCET LKWTVNGDTR VGLFAVCDIP AGTELTFNYN LDCLGNEKTV CRCGASNCSG 1210 1220 1230 1240 1250 1260 FLGDRPKTSA SLSSEEKGKK AKKKTRRRRA KGEGKRQSED ECFRCGDGGQ LVLCDRKFCT 1270 1280 1290 1300 1310 1320 KAYHLSCLGL GKRPFGKWEC PWHHCDVCGK PSTSFCHLCP NSFCKEHQDG TAFRSTQDGQ 1330 1340 1350 1360 SYCCEHDLRA DSSSSTKTEK PFPESLKSKG KRKKRRCWRR VTDGK
	Isoform 2. Checksum: 28858A53E6156DEF	FASTA	1,366	152,381
	10 20 30 40 50 60 MEFSIRKSPL SVQKVVKCMK MKQTPEILGS ANGKTQNCEV NHECSVFLSK AQLSNSLQEG 70 80 90 100 110 120 VMQKFNGHDA LPFLPAEKLK DLTSCVFNGE PGAHDTKLCF EAQEVKGIGT PPNTTPIKNG 130 140 150 160 170 180 SPEIKLKITK TYMNGKPLFE SSICGDGAAD VSQSEENEQK SDNKTRRNRK RSIKYDSLLE 190 200 210 220 230 240 QGLVEAALVS KISSPADKKI PVKKESCPNT GRDRDLLLKY NVGDLVWSKV SGYPWWPCMV 250 260 270 280 290 300 SADPLLHNHT KLKGQKKSAR QYHVQFFGDA PERAWIFEKS LVAFEGEEQF EKLCQESAKQ 310 320 330 340 350 360 APTKAEKIKL LKPISGRLRA QWEMGIVQAE EAASMSIEER KAKFTFLYVG DQLHLNPQVA 370 380 390 400 410 420 KEAGIVTEPL GEMVDSSGAS EEAAVDPGSV REEDIPTKRR RRTKRSSSAE NQEGDPGTDK 430 440 450 460 470 480 STPPKMAEAE PKRGVGSPAG RKKSTGSAPR SRKGDSAAQF LVFCQKHRDE VVAEHPDASG 490 500 510 520 530 540 EEIEELLGSQ WSMLNEKQKA RYNTKFSLMI SAQSEEDSGN GNGKKRSHTK RADDPAEDVD 550 560 570 580 590 600 VEDAPRKRLR ADKHSLRKQR ETITDKTART SSYKAIEAAS SLKSQAATKN LSDACKPLKK 610 620 630 640 650 660 RNRASATASS ALGFNKSSSP SASLTEHEVS DSPGDEPSES PYESADETQT EASVSSKKSE 670 680 690 700 710 720 RGMAAKKEYV CQLCEKTGSL LLCEGPCCGA FHLACLGLSR RPEGRFTCTE CASGIHSCFV 730 740 750 760 770 780 CKESKMEVKR CVVNQCGKFY HEACVKKYPL TVFESRGFRC PLHSCMSCHA SNPSNPRPSK 790 800 810 820 830 840 GKMMRCVRCP VAYHGGDACL AAGCSVIASN SIICTGHFTA RKGKRHHTHV NVSWCFVCSK 850 860 870 880 890 900 GGSLLCCEAC PAAFHPDCLN IEMPDGSWFC NDCRAGKKLH FQDIIWVKLG NYRWWPAEVC 910 920 930 940 950 960 HPKNVPPNIQ KMKHEIGEFP VFFFGSKDYY WTHQARVFPY MEGDRGSRYQ GVRGIGRVFK 970 980 990 1000 1010 1020 NALQEAEARF NEVKLQREAR ETQESERKPP PYKHIKVNKP YGKVQIYTAD ISEIPKCNCK 1030 1040 1050 1060 1070 1080 PTDENPCGSD SECLNRMLMF ECHPQVCPAG EYCQNQCFTK RQYPETKIIK TDGKGWGLVA 1090 1100 1110 1120 1130 1140 KRDIRKGEFV NEYVGELIDE EECMARIKYA HENDITHFYM LTIDKDRIID AGPKGNYSRF 1150 1160 1170 1180 1190 1200 MNHSCQPNCE TLKWTVNGDT RVGLFAVCDI PAGTELTFNY NLDCLGNEKT VCRCGASNCS 1210 1220 1230 1240 1250 1260 GFLGDRPKTS ASLSSEEKGK KAKKKTRRRR AKGEGKRQSE DECFRCGDGG QLVLCDRKFC 1270 1280 1290 1300 1310 1320 TKAYHLSCLG LGKRPFGKWE CPWHHCDVCG KPSTSFCHLC PNSFCKEHQD GTAFRSTQDG 1330 1340 1350 1360 QSYCCEHDLR ADSSSSTKTE KPFPESLKSK GKRKKRRCWR RVTDGK
	Isoform 3. Checksum: EE0EF9742565F18D	FASTA	847	95,042
	10 20 30 40 50 60 MGMGKKRSHT KRADDPAEDV DVEDAPRKRL RADKHSLRKQ RETITDKTAR TSSYKAIEAA 70 80 90 100 110 120 SSLKSQAATK NLSDACKPLK KRNRASATAS SALGFNKSSS PSASLTEHEV SDSPGDEPSE 130 140 150 160 170 180 SPYESADETQ TEASVSSKKS ERGMAAKKEY VCQLCEKTGS LLLCEGPCCG AFHLACLGLS 190 200 210 220 230 240 RRPEGRFTCT ECASGIHSCF VCKESKMEVK RCVVNQCGKF YHEACVKKYP LTVFESRGFR 250 260 270 280 290 300 CPLHSCMSCH ASNPSNPRPS KGKMMRCVRC PVAYHGGDAC LAAGCSVIAS NSIICTGHFT 310 320 330 340 350 360 ARKGKRHHTH VNVSWCFVCS KGGSLLCCEA CPAAFHPDCL NIEMPDGSWF CNDCRAGKKL 370 380 390 400 410 420 HFQDIIWVKL GNYRWWPAEV CHPKNVPPNI QKMKHEIGEF PVFFFGSKDY YWTHQARVFP 430 440 450 460 470 480 YMEGDRGSRY QGVRGIGRVF KNALQEAEAR FNEVKLQREA RETQESERKP PPYKHIKVNK 490 500 510 520 530 540 PYGKVQIYTA DISEIPKCNC KPTDENPCGS DSECLNRMLM FECHPQVCPA GEYCQNQCFT 550 560 570 580 590 600 KRQYPETKII KTDGKGWGLV AKRDIRKGEF VNEYVGELID EEECMARIKY AHENDITHFY 610 620 630 640 650 660 MLTIDKDRII DAGPKGNYSR FMNHSCQPNC ETLKWTVNGD TRVGLFAVCD IPAGTELTFN 670 680 690 700 710 720 YNLDCLGNEK TVCRCGASNC SGFLGDRPKT SASLSSEEKG KKAKKKTRRR RAKGEGKRQS 730 740 750 760 770 780 EDECFRCGDG GQLVLCDRKF CTKAYHLSCL GLGKRPFGKW ECPWHHCDVC GKPSTSFCHL 790 800 810 820 830 840 CPNSFCKEHQ DGTAFRSTQD GQSYCCEHDL RADSSSSTKT EKPFPESLKS KGKRKKRRCW RRVTDGK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H. DNA Res. 10:167-180(2003) [PubMed: 14621295] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Embryonic tail.
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 446-1365 (ISOFORM 1). Strain: C57BL/6J. Tissue: Adrenal gland.
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 516-1365 (ISOFORM 2). Strain: FVB/N. Tissue: Limb and Mammary tumor.
[5]	"WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma." Stec I., Wright T.J., van Ommen G.-J.B., de Boer P.A., van Haeringen A., Moorman A.F.M., Altherr M.R., den Dunnen J.T. Hum. Mol. Genet. 7:1071-1082(1998) [PubMed: 9618163] [Abstract] Cited for: TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
[6]	Erratum Stec I., Wright T.J., van Ommen G.-J.B., de Boer P.A., van Haeringen A., Moorman A.F.M., Altherr M.R., den Dunnen J.T. Hum. Mol. Genet. 7:1527-1527(1998)
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK129287 mRNA. Translation: BAC98097.1. Different initiation. AC163329 Genomic DNA. No translation available. AK078622 mRNA. Translation: BAC37342.1. Frameshift. BC046473 mRNA. Translation: AAH46473.1. BC053454 mRNA. Translation: AAH53454.1.
IPI	IPI00107975. IPI00671804. IPI00762411.
UniGene	Mm.19892 Mm.332320 Mm.456405 Mm.460382
3D structure databases
HSSP	HSSP built from PDB template 1F62 based on UniProtKB Q9UIG0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8BVE8.
PTM databases
PhosphoSite	Q8BVE8.
Proteomic databases
PRIDE	Q8BVE8.
Genome annotation databases
Ensembl	ENSMUST00000058096; ENSMUSP00000058940; ENSMUSG00000057406; Mus musculus. [Genome view] ENSMUST00000066854; ENSMUSP00000067205; ENSMUSG00000057406; Mus musculus. [Genome view] ENSMUST00000075812; ENSMUSP00000075210; ENSMUSG00000057406; Mus musculus. [Genome view]
UCSC	uc008xbk.1. mouse. uc008xbm.1. mouse.
Organism-specific databases
MGI	MGI:1276574. Whsc1.
Rouge	Search...
Phylogenomic databases
HOVERGEN	Q8BVE8.
OMA	CWRRVTE.
Enzyme and pathway databases
BRENDA	2.1.1.43. 244.
Gene expression databases
ArrayExpress	Q8BVE8.
Bgee	Q8BVE8.
CleanEx	MM_WHSC1.
Genevestigator	Q8BVE8.
GermOnline	ENSMUSG00000057406. Mus musculus.
Family and domain databases
InterPro	IPR006560. AWS. IPR000910. HMG_HMG1/HMG2. IPR003616. Post-SET_Zn_bd. IPR000313. PWWP. IPR001214. SET. IPR019786. Zinc_finger_PHD-type_CS. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR001841. Znf_RING. [Graphical view]
Gene3D	G3DSA:1.10.30.10. HMG-box. 1 hit.
Pfam	PF00505. HMG_box. 1 hit. PF00628. PHD. 3 hits. PF00855. PWWP. 2 hits. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00570. AWS. 1 hit. SM00398. HMG. 1 hit. SM00249. PHD. 4 hits. SM00508. PostSET. 1 hit. SM00293. PWWP. 2 hits. SM00184. RING. 2 hits. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS51215. AWS. 1 hit. PS50118. HMG_BOX_2. 1 hit. PS50868. POST_SET. 1 hit. PS50812. PWWP. 2 hits. PS50280. SET. 1 hit. PS01359. ZF_PHD_1. 2 hits. PS50016. ZF_PHD_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

NSD2_MOUSE

Accession

Primary (citable) accession number: Q8BVE8
Secondary accession number(s): Q6ZPY1, Q7TSF5, Q811F0

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	October 31, 2006
Last modified:	November 3, 2009
This is version 58 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)