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Protein

Complement C1q tumor necrosis factor-related protein 7

Gene

C1qtnf7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • protein homooligomerization Source: MGI

Names & Taxonomyi

Protein namesi
Recommended name:
Complement C1q tumor necrosis factor-related protein 7
Gene namesi
Name:C1qtnf7
Synonyms:Ctrp7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1925911. C1qtnf7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_000000354017 – 289Complement C1q tumor necrosis factor-related protein 7Add BLAST273

Proteomic databases

MaxQBiQ8BVD7.
PaxDbiQ8BVD7.
PRIDEiQ8BVD7.

PTM databases

iPTMnetiQ8BVD7.
PhosphoSitePlusiQ8BVD7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000061535.
CleanExiMM_C1QTNF7.
ExpressionAtlasiQ8BVD7. baseline and differential.
GenevisibleiQ8BVD7. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000126974.

Structurei

3D structure databases

ProteinModelPortaliQ8BVD7.
SMRiQ8BVD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 139Collagen-likeAdd BLAST102
Domaini143 – 279C1qPROSITE-ProRule annotationAdd BLAST137

Keywords - Domaini

Collagen, Signal

Phylogenomic databases

eggNOGiENOG410IFQ7. Eukaryota.
ENOG410ZWEM. LUCA.
GeneTreeiENSGT00760000118830.
HOGENOMiHOG000085653.
HOVERGENiHBG108220.
InParanoidiQ8BVD7.
PhylomeDBiQ8BVD7.
TreeFamiTF329591.

Family and domain databases

Gene3Di2.160.20.50. 1 hit.
2.60.120.40. 1 hit.
InterProiView protein in InterPro
IPR001073. C1q_dom.
IPR008160. Collagen.
IPR016133. Insect_cyst_antifreeze_prot.
IPR008983. Tumour_necrosis_fac-like_dom.
PfamiView protein in Pfam
PF00386. C1q. 1 hit.
PF01391. Collagen. 2 hits.
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiView protein in SMART
SM00110. C1Q. 1 hit.
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiView protein in PROSITE
PS50871. C1Q. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8BVD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVLLYVTSL AICASGQPRA NQAKGESYSP RYICSIPGLP GPPGPPGANG
60 70 80 90 100
SPGPHGRIGL PGRDGRDGRK GEKGEKGTAG LKGKTGPLGL AGEKGDQGET
110 120 130 140 150
GKKGPIGPEG EKGEVGPAGP PGPKGDRGDQ GDPGLPGVCR CGSIVLKSAF
160 170 180 190 200
SVGITTSYPE ERLPIIFNKV LFNEGEHYNP ATGKFICAFP GIYYFSYDIT
210 220 230 240 250
LANKHLAIGL VHNGQYRIRT FDANTGNHDV ASGSTVIYLQ PEDEVWLEIF
260 270 280
FNDQNGLFSD PGWADSLFSG FLLYVDTDYL DSISEDDEL
Length:289
Mass (Da):30,517
Last modified:April 26, 2005 - v2
Checksum:i45ED4E3C88E92CCB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti20A → P in BAC37409 (PubMed:16141072).Curated1
Sequence conflicti193Y → C in BAC37409 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK078818 mRNA. Translation: BAC37409.1.
BC038308 mRNA. Translation: AAH38308.1.
CCDSiCCDS19262.1.
RefSeqiNP_001128644.1. NM_001135172.1.
NP_780634.2. NM_175425.4.
XP_006503728.1. XM_006503665.3.
UniGeneiMm.275553.

Genome annotation databases

EnsembliENSMUST00000121872; ENSMUSP00000113520; ENSMUSG00000061535.
GeneIDi109323.
KEGGimmu:109323.
UCSCiuc008xho.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiC1QT7_MOUSE
AccessioniPrimary (citable) accession number: Q8BVD7
Secondary accession number(s): Q8CHX9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 25, 2017
This is version 106 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot