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Protein

Tigger transposable element-derived protein 4

Gene

Tigd4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi39 – 59H-T-H motifBy similarityAdd BLAST21
DNA bindingi108 – 139H-T-H motifBy similarityAdd BLAST32

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tigger transposable element-derived protein 4
Gene namesi
Name:Tigd4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:2685264. Tigd4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002726171 – 513Tigger transposable element-derived protein 4Add BLAST513

Proteomic databases

PaxDbiQ8BUZ3.
PRIDEiQ8BUZ3.

PTM databases

iPTMnetiQ8BUZ3.
PhosphoSitePlusiQ8BUZ3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000047819.
CleanExiMM_TIGD4.

Interactioni

Protein-protein interaction databases

IntActiQ8BUZ3. 4 interactors.
STRINGi10090.ENSMUSP00000052320.

Structurei

3D structure databases

ProteinModelPortaliQ8BUZ3.
SMRiQ8BUZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 63HTH psq-typePROSITE-ProRule annotationAdd BLAST52
Domaini75 – 146HTH CENPB-typePROSITE-ProRule annotationAdd BLAST72
Domaini174 – 375DDE-1Sequence analysisAdd BLAST202

Sequence similaritiesi

Contains 1 DDE-1 domain.Sequence analysis
Contains 1 HTH CENPB-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 HTH psq-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3105. Eukaryota.
ENOG4110CDI. LUCA.
GeneTreeiENSGT00760000119149.
HOGENOMiHOG000154580.
HOVERGENiHBG086852.
InParanoidiQ8BUZ3.
OMAiGFKSQQG.
OrthoDBiEOG091G0G48.
PhylomeDBiQ8BUZ3.
TreeFamiTF101131.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR004875. DDE_SF_endonuclease_dom.
IPR009057. Homeodomain-like.
IPR006600. HTH_CenpB_DNA-bd_dom.
IPR007889. HTH_Psq.
[Graphical view]
PfamiPF04218. CENP-B_N. 1 hit.
PF03184. DDE_1. 1 hit.
PF03221. HTH_Tnp_Tc5. 1 hit.
[Graphical view]
SMARTiSM00674. CENPB. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51253. HTH_CENPB. 1 hit.
PS50960. HTH_PSQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BUZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEASVDIGT QPVTVKKKKS LSIEEKIDII NAVESGKKKA EIAAEYGIKK
60 70 80 90 100
NSLSSIMKNK DKVLEAFESL RFDPKRKRLR TAFYTDLEEA LMRWYRIAQC
110 120 130 140 150
LNVPVNGPML RLKANDFAQK LGHNDFKCSN GWLDRFKSRY GLVFRAQPVE
160 170 180 190 200
ATGISIDPST VWYQNVLPYY LNDYHPKNVF NVKETGLLYR MLPTNTFAFK
210 220 230 240 250
GETCSVGKLC KDRITLALGT NMDGSEKLPL LIIGKNRAPR CFKGIKSLPV
260 270 280 290 300
YYEANRTAWM TAAIFEQWMQ KLDEKFQAQK RRVVIFVDSC PAHPEVKNLK
310 320 330 340 350
SIELAFFPSC LSSGFAAMNQ GVIKSLKIKY RHCLIKKFLS SVESSKEFTF
360 370 380 390 400
SLLDAVDTLH LCWRAVTPET IVKSYEEAGF RSPKGENDTA NADAAVALDL
410 420 430 440 450
TAHAVGAGVE FLEGLSIEEY AALDEDLETC EATQKDDAEW AGESKQDETG
460 470 480 490 500
LYTSDEEEED SGALEVDLPS PSKKDALSAV GTLKRFLRSH DLNDELHGSL
510
ADLENFINAL SPK
Length:513
Mass (Da):57,472
Last modified:March 1, 2003 - v1
Checksum:i8B756E0F693AD2A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK081667 mRNA. Translation: BAC38284.1.
CCDSiCCDS17439.1.
RefSeqiNP_997161.1. NM_207278.2.
UniGeneiMm.83086.

Genome annotation databases

EnsembliENSMUST00000062623; ENSMUSP00000052320; ENSMUSG00000047819.
GeneIDi403175.
KEGGimmu:403175.
UCSCiuc008pqh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK081667 mRNA. Translation: BAC38284.1.
CCDSiCCDS17439.1.
RefSeqiNP_997161.1. NM_207278.2.
UniGeneiMm.83086.

3D structure databases

ProteinModelPortaliQ8BUZ3.
SMRiQ8BUZ3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8BUZ3. 4 interactors.
STRINGi10090.ENSMUSP00000052320.

PTM databases

iPTMnetiQ8BUZ3.
PhosphoSitePlusiQ8BUZ3.

Proteomic databases

PaxDbiQ8BUZ3.
PRIDEiQ8BUZ3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000062623; ENSMUSP00000052320; ENSMUSG00000047819.
GeneIDi403175.
KEGGimmu:403175.
UCSCiuc008pqh.1. mouse.

Organism-specific databases

CTDi201798.
MGIiMGI:2685264. Tigd4.

Phylogenomic databases

eggNOGiKOG3105. Eukaryota.
ENOG4110CDI. LUCA.
GeneTreeiENSGT00760000119149.
HOGENOMiHOG000154580.
HOVERGENiHBG086852.
InParanoidiQ8BUZ3.
OMAiGFKSQQG.
OrthoDBiEOG091G0G48.
PhylomeDBiQ8BUZ3.
TreeFamiTF101131.

Miscellaneous databases

PROiQ8BUZ3.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000047819.
CleanExiMM_TIGD4.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR004875. DDE_SF_endonuclease_dom.
IPR009057. Homeodomain-like.
IPR006600. HTH_CenpB_DNA-bd_dom.
IPR007889. HTH_Psq.
[Graphical view]
PfamiPF04218. CENP-B_N. 1 hit.
PF03184. DDE_1. 1 hit.
PF03221. HTH_Tnp_Tc5. 1 hit.
[Graphical view]
SMARTiSM00674. CENPB. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51253. HTH_CENPB. 1 hit.
PS50960. HTH_PSQ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTIGD4_MOUSE
AccessioniPrimary (citable) accession number: Q8BUZ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.